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Results: 1 to 20 of 41

1.

Huntingtin is required for normal excitatory synapse development in cortical and striatal circuits.

McKinstry SU, Karadeniz YB, Worthington AK, Hayrapetyan VY, Ozlu MI, Serafin-Molina K, Risher WC, Ustunkaya T, Dragatsis I, Zeitlin S, Yin HH, Eroglu C.

J Neurosci. 2014 Jul 9;34(28):9455-72. doi: 10.1523/JNEUROSCI.4699-13.2014.

PMID:
25009276
[PubMed - in process]
2.

IKAP deficiency in an FD mouse model and in oligodendrocyte precursor cells results in downregulation of genes involved in oligodendrocyte differentiation and myelin formation.

Cheishvili D, Dietrich P, Maayan C, Even A, Weil M, Dragatsis I, Razin A.

PLoS One. 2014 Apr 23;9(4):e94612. doi: 10.1371/journal.pone.0094612. eCollection 2014.

PMID:
24760006
[PubMed - in process]
Free PMC Article
3.

Cutting edge: Conditional MHC class II expression reveals a limited role for B cell antigen presentation in primary and secondary CD4 T cell responses.

Archambault AS, Carrero JA, Barnett LG, McGee NG, Sim J, Wright JO, Raabe T, Chen P, Ding H, Allenspach EJ, Dragatsis I, Laufer TM, Wu GF.

J Immunol. 2013 Jul 15;191(2):545-50. doi: 10.4049/jimmunol.1201598. Epub 2013 Jun 14.

PMID:
23772037
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

IKAP expression levels modulate disease severity in a mouse model of familial dysautonomia.

Dietrich P, Alli S, Shanmugasundaram R, Dragatsis I.

Hum Mol Genet. 2012 Dec 1;21(23):5078-90. doi: 10.1093/hmg/dds354. Epub 2012 Aug 24.

PMID:
22922231
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Deletion of exon 20 of the Familial Dysautonomia gene Ikbkap in mice causes developmental delay, cardiovascular defects, and early embryonic lethality.

Dietrich P, Yue J, E S, Dragatsis I.

PLoS One. 2011;6(10):e27015. doi: 10.1371/journal.pone.0027015. Epub 2011 Oct 28.

PMID:
22046433
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease.

Keryer G, Pineda JR, Liot G, Kim J, Dietrich P, Benstaali C, Smith K, Cordelières FP, Spassky N, Ferrante RJ, Dragatsis I, Saudou F.

J Clin Invest. 2011 Nov;121(11):4372-82. doi: 10.1172/JCI57552. Epub 2011 Oct 10.

PMID:
21985783
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Genetics and neuropathology of Huntington's disease.

Reiner A, Dragatsis I, Dietrich P.

Int Rev Neurobiol. 2011;98:325-72. doi: 10.1016/B978-0-12-381328-2.00014-6. Review.

PMID:
21907094
[PubMed - indexed for MEDLINE]
8.

Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis.

Godin JD, Colombo K, Molina-Calavita M, Keryer G, Zala D, Charrin BC, Dietrich P, Volvert ML, Guillemot F, Dragatsis I, Bellaiche Y, Saudou F, Nguyen L, Humbert S.

Neuron. 2010 Aug 12;67(3):392-406. doi: 10.1016/j.neuron.2010.06.027.

PMID:
20696378
[PubMed - indexed for MEDLINE]
Free Article
9.

α8-integrins are required for hippocampal long-term potentiation but not for hippocampal-dependent learning.

Chan CS, Chen H, Bradley A, Dragatsis I, Rosenmund C, Davis RL.

Genes Brain Behav. 2010 Jun 1;9(4):402-10. doi: 10.1111/j.1601-183X.2010.00569.x. Epub 2010 Jan 30.

PMID:
20132319
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Presenilins are essential for regulating neurotransmitter release.

Zhang C, Wu B, Beglopoulos V, Wines-Samuelson M, Zhang D, Dragatsis I, Südhof TC, Shen J.

Nature. 2009 Jul 30;460(7255):632-6. doi: 10.1038/nature08177.

PMID:
19641596
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The hormonal action of IGF1 in postnatal mouse growth.

Stratikopoulos E, Szabolcs M, Dragatsis I, Klinakis A, Efstratiadis A.

Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19378-83. doi: 10.1073/pnas.0809223105. Epub 2008 Nov 25.

PMID:
19033454
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

CAG repeat lengths > or =335 attenuate the phenotype in the R6/2 Huntington's disease transgenic mouse.

Dragatsis I, Goldowitz D, Del Mar N, Deng YP, Meade CA, Liu L, Sun Z, Dietrich P, Yue J, Reiner A.

Neurobiol Dis. 2009 Mar;33(3):315-30. doi: 10.1016/j.nbd.2008.10.009. Epub 2008 Nov 6.

PMID:
19027857
[PubMed - indexed for MEDLINE]
13.

Congenital hydrocephalus associated with abnormal subcommissural organ in mice lacking huntingtin in Wnt1 cell lineages.

Dietrich P, Shanmugasundaram R, Shuyu E, Dragatsis I.

Hum Mol Genet. 2009 Jan 1;18(1):142-50. doi: 10.1093/hmg/ddn324. Epub 2008 Oct 6.

PMID:
18838463
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Elucidating a normal function of huntingtin by functional and microarray analysis of huntingtin-null mouse embryonic fibroblasts.

Zhang H, Das S, Li QZ, Dragatsis I, Repa J, Zeitlin S, Hajnóczky G, Bezprozvanny I.

BMC Neurosci. 2008 Apr 15;9:38. doi: 10.1186/1471-2202-9-38.

PMID:
18412970
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A transgenic mouse class-III beta tubulin reporter using yellow fluorescent protein.

Liu L, Geisert EE, Frankfurter A, Spano AJ, Jiang CX, Yue J, Dragatsis I, Goldowitz D.

Genesis. 2007 Sep;45(9):560-9.

PMID:
17868115
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia.

Baranova O, Miranda LF, Pichiule P, Dragatsis I, Johnson RS, Chavez JC.

J Neurosci. 2007 Jun 6;27(23):6320-32.

PMID:
17554006
[PubMed - indexed for MEDLINE]
Free Article
17.

Huntingtin inhibits caspase-3 activation.

Zhang Y, Leavitt BR, van Raamsdonk JM, Dragatsis I, Goldowitz D, MacDonald ME, Hayden MR, Friedlander RM.

EMBO J. 2006 Dec 13;25(24):5896-906. Epub 2006 Nov 23.

PMID:
17124493
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Neuronal deletion of Lepr elicits diabesity in mice without affecting cold tolerance or fertility.

McMinn JE, Liu SM, Liu H, Dragatsis I, Dietrich P, Ludwig T, Boozer CN, Chua SC Jr.

Am J Physiol Endocrinol Metab. 2005 Sep;289(3):E403-11. Epub 2005 May 3.

PMID:
15870101
[PubMed - indexed for MEDLINE]
Free Article
19.

Brain-specific knock-out of hypoxia-inducible factor-1alpha reduces rather than increases hypoxic-ischemic damage.

Helton R, Cui J, Scheel JR, Ellison JA, Ames C, Gibson C, Blouw B, Ouyang L, Dragatsis I, Zeitlin S, Johnson RS, Lipton SA, Barlow C.

J Neurosci. 2005 Apr 20;25(16):4099-107. Erratum in: J Neurosci. 2005 May 11;25(19):1 p following 4888.

PMID:
15843612
[PubMed - indexed for MEDLINE]
Free Article
20.

Huntingtin-associated protein 1 (Hap1) mutant mice bypassing the early postnatal lethality are neuroanatomically normal and fertile but display growth retardation.

Dragatsis I, Zeitlin S, Dietrich P.

Hum Mol Genet. 2004 Dec 15;13(24):3115-25. Epub 2004 Oct 20.

PMID:
15496430
[PubMed - indexed for MEDLINE]
Free Article

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