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Results: 1 to 20 of 36

1.

Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives.

Ozaki E, Campbell M, Doyle SL.

J Inflamm Res. 2015 Jan 16;8:15-27. doi: 10.2147/JIR.S51250. eCollection 2015. Review.

2.

Interleukin-18 bioactivity and dose: data interpretation at a crossroads.

Doyle SL, Adamson P, López FJ, Humphries P, Campbell M.

Invest Ophthalmol Vis Sci. 2014 Dec 23;55(12):8349-50. doi: 10.1167/iovs.14-15786. No abstract available.

PMID:
25538010
3.

Reply to IL-18 is not therapeutic for neovascular age-related macular degeneration.

Doyle SL, Adamson P, López FJ, Humphries P, Campbell M.

Nat Med. 2014 Dec;20(12):1376-7. doi: 10.1038/nm.3741. No abstract available.

PMID:
25473915
4.

TRAM is required for TLR2 endosomal signaling to type I IFN induction.

Stack J, Doyle SL, Connolly DJ, Reinert LS, O'Keeffe KM, McLoughlin RM, Paludan SR, Bowie AG.

J Immunol. 2014 Dec 15;193(12):6090-102. doi: 10.4049/jimmunol.1401605. Epub 2014 Nov 10.

PMID:
25385819
5.

IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration.

Doyle SL, Ozaki E, Brennan K, Humphries MM, Mulfaul K, Keaney J, Kenna PF, Maminishkis A, Kiang AS, Saunders SP, Hams E, Lavelle EC, Gardiner C, Fallon PG, Adamson P, Humphries P, Campbell M.

Sci Transl Med. 2014 Apr 2;6(230):230ra44. doi: 10.1126/scitranslmed.3007616.

6.

An overview of the involvement of interleukin-18 in degenerative retinopathies.

Campbell M, Doyle SL, Ozaki E, Kenna PF, Kiang AS, Humphries MM, Humphries P.

Adv Exp Med Biol. 2014;801:409-15. doi: 10.1007/978-1-4614-3209-8_52. Review.

PMID:
24664725
7.

Inflammation in age-related macular degeneration.

Ozaki E, Campbell M, Kiang AS, Humphries M, Doyle SL, Humphries P.

Adv Exp Med Biol. 2014;801:229-35. doi: 10.1007/978-1-4614-3209-8_30. Review.

PMID:
24664703
8.

Plasmonics-enhanced and optically modulated delivery of gold nanostars into brain tumor.

Yuan H, Wilson CM, Xia J, Doyle SL, Li S, Fales AM, Liu Y, Ozaki E, Mulfaul K, Hanna G, Palmer GM, Wang LV, Grant GA, Vo-Dinh T.

Nanoscale. 2014 Apr 21;6(8):4078-82. doi: 10.1039/c3nr06770j. Epub 2014 Mar 11.

PMID:
24619405
9.

The role of obesity in gastrointestinal cancer: evidence and opinion.

Donohoe CL, O'Farrell NJ, Doyle SL, Reynolds JV.

Therap Adv Gastroenterol. 2014 Jan;7(1):38-50. doi: 10.1177/1756283X13501786. Review.

10.

Bruton's tyrosine kinase mediates the synergistic signalling between TLR9 and the B cell receptor by regulating calcium and calmodulin.

Kenny EF, Quinn SR, Doyle SL, Vink PM, van Eenennaam H, O'Neill LA.

PLoS One. 2013 Aug 14;8(8):e74103. doi: 10.1371/journal.pone.0074103. eCollection 2013.

11.

Nuclear factor κB2 p52 protein has a role in antiviral immunity through IκB kinase epsilon-dependent induction of Sp1 protein and interleukin 15.

Doyle SL, Shirey KA, McGettrick AF, Kenny EF, Carpenter S, Caffrey BE, Gargan S, Quinn SR, Caamaño JH, Moynagh P, Vogel SN, O'Neill LA.

J Biol Chem. 2013 Aug 30;288(35):25066-75. doi: 10.1074/jbc.M113.469122. Epub 2013 Jul 19.

12.

An eye on the future of inflammasomes and drug development in AMD.

Campbell M, Doyle SL.

J Mol Med (Berl). 2013 Sep;91(9):1059-70. doi: 10.1007/s00109-013-1050-0. Epub 2013 May 10. Review.

PMID:
23661041
13.

Establishing computed tomography-defined visceral fat area thresholds for use in obesity-related cancer research.

Doyle SL, Bennett AM, Donohoe CL, Mongan AM, Howard JM, Lithander FE, Pidgeon GP, Reynolds JV, Lysaght J.

Nutr Res. 2013 Mar;33(3):171-9. doi: 10.1016/j.nutres.2012.12.007. Epub 2013 Jan 30.

PMID:
23507222
14.

Conjugated linoleic acid suppresses IRF3 activation via modulation of CD14.

Dowling JK, McCoy CE, Doyle SL, BenLarbi N, Canavan M, O'Neill LA, Loscher CE.

J Nutr Biochem. 2013 May;24(5):920-8. doi: 10.1016/j.jnutbio.2012.06.010. Epub 2012 Aug 15.

PMID:
22901688
15.

NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components.

Doyle SL, Campbell M, Ozaki E, Salomon RG, Mori A, Kenna PF, Farrar GJ, Kiang AS, Humphries MM, Lavelle EC, O'Neill LA, Hollyfield JG, Humphries P.

Nat Med. 2012 May;18(5):791-8. doi: 10.1038/nm.2717.

16.

The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation.

Doyle SL, Husebye H, Connolly DJ, Espevik T, O'Neill LA, McGettrick AF.

Nat Commun. 2012 Feb 28;3:707. doi: 10.1038/ncomms1706.

PMID:
22426228
17.

Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma.

Donohoe CL, Doyle SL, McGarrigle S, Cathcart MC, Daly E, O'Grady A, Lysaght J, Pidgeon GP, Reynolds JV.

Br J Surg. 2012 Mar;99(3):387-96. doi: 10.1002/bjs.8658. Epub 2012 Jan 12.

PMID:
22241325
18.

Outcomes of implementing rapid triage in the pediatric emergency department.

Doyle SL, Kingsnorth J, Guzzetta CE, Jahnke SA, McKenna JC, Brown K.

J Emerg Nurs. 2012 Jan;38(1):30-5. doi: 10.1016/j.jen.2010.08.013. Epub 2011 Jan 22.

PMID:
22226134
19.

IGF-1 and its receptor in esophageal cancer: association with adenocarcinoma and visceral obesity.

Doyle SL, Donohoe CL, Finn SP, Howard JM, Lithander FE, Reynolds JV, Pidgeon GP, Lysaght J.

Am J Gastroenterol. 2012 Feb;107(2):196-204. doi: 10.1038/ajg.2011.417. Epub 2011 Dec 6.

PMID:
22146489
20.

Visceral obesity, metabolic syndrome, insulin resistance and cancer.

Doyle SL, Donohoe CL, Lysaght J, Reynolds JV.

Proc Nutr Soc. 2012 Feb;71(1):181-9. doi: 10.1017/S002966511100320X. Epub 2011 Nov 3.

PMID:
22051112
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