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Results: 1 to 20 of 194


Introduction to the 57th annual Thomas L. Petty aspen lung conference: rebuilding the injured lung.

Riches DW, Burnham EL, Moss M, Downey GP, Schmidt EP.

Ann Am Thorac Soc. 2015 Mar;12 Suppl 1:S1-2. doi: 10.1513/AnnalsATS.201411-536MG. No abstract available.


Matrix metalloproteinases and protein tyrosine kinases: potential novel targets in acute lung injury and ARDS.

Aschner Y, Zemans RL, Yamashita CM, Downey GP.

Chest. 2014 Oct;146(4):1081-91. doi: 10.1378/chest.14-0397. Review.


Divergent functions of Toll-like receptors during bacterial lung infections.

Baral P, Batra S, Zemans RL, Downey GP, Jeyaseelan S.

Am J Respir Crit Care Med. 2014 Oct 1;190(7):722-32. doi: 10.1164/rccm.201406-1101PP. Review.


The importance of matrix metalloproteinase-3 in respiratory disorders.

Yamashita CM, Radisky DC, Aschner Y, Downey GP.

Expert Rev Respir Med. 2014 Aug;8(4):411-21. doi: 10.1586/17476348.2014.909288. Epub 2014 May 29. Review.


Interactions of the protein-tyrosine phosphatase-α with the focal adhesion targeting domain of focal adhesion kinase are involved in interleukin-1 signaling in fibroblasts.

Wang Q, Wang Y, Fritz D, Rajshankar D, Downey GP, McCulloch CA.

J Biol Chem. 2014 Jun 27;289(26):18427-41. doi: 10.1074/jbc.M113.540294. Epub 2014 May 12.


Investigating the role of nucleotide-binding oligomerization domain-like receptors in bacterial lung infection.

Leissinger M, Kulkarni R, Zemans RL, Downey GP, Jeyaseelan S.

Am J Respir Crit Care Med. 2014 Jun 15;189(12):1461-8. doi: 10.1164/rccm.201311-2103PP. Review.


Protein tyrosine phosphatase α mediates profibrotic signaling in lung fibroblasts through TGF-β responsiveness.

Aschner Y, Khalifah AP, Briones N, Yamashita C, Dolgonos L, Young SK, Campbell MN, Riches DW, Redente EF, Janssen WJ, Henson PM, Sap J, Vacaresse N, Kapus A, McCulloch CA, Zemans RL, Downey GP.

Am J Pathol. 2014 May;184(5):1489-502. doi: 10.1016/j.ajpath.2014.01.016. Epub 2014 Mar 17.


Tumor necrosis factor-α accelerates the resolution of established pulmonary fibrosis in mice by targeting profibrotic lung macrophages.

Redente EF, Keith RC, Janssen W, Henson PM, Ortiz LA, Downey GP, Bratton DL, Riches DW.

Am J Respir Cell Mol Biol. 2014 Apr;50(4):825-37. doi: 10.1165/rcmb.2013-0386OC.


Serum VEGF-D a concentration as a biomarker of lymphangioleiomyomatosis severity and treatment response: a prospective analysis of the Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus (MILES) trial.

Young L, Lee HS, Inoue Y, Moss J, Singer LG, Strange C, Nakata K, Barker AF, Chapman JT, Brantly ML, Stocks JM, Brown KK, Lynch JP 3rd, Goldberg HJ, Downey GP, Swigris JJ, Taveira-DaSilva AM, Krischer JP, Trapnell BC, McCormack FX; MILES Trial Group.

Lancet Respir Med. 2013 Aug;1(6):445-52.


Role of PTPα in the destruction of periodontal connective tissues.

Rajshankar D, Sima C, Wang Q, Goldberg SR, Kazembe M, Wang Y, Glogauer M, Downey GP, McCulloch CA.

PLoS One. 2013 Aug 5;8(8):e70659. doi: 10.1371/journal.pone.0070659. Print 2013.


Neutrophil intercellular communication in acute lung injury. Emerging roles of microparticles and gap junctions.

Dengler V, Downey GP, Tuder RM, Eltzschig HK, Schmidt EP.

Am J Respir Cell Mol Biol. 2013 Jul;49(1):1-5. doi: 10.1165/rcmb.2012-0472TR. Review.


The fibroproliferative response in acute respiratory distress syndrome: mechanisms and clinical significance.

Burnham EL, Janssen WJ, Riches DW, Moss M, Downey GP.

Eur Respir J. 2014 Jan;43(1):276-85. doi: 10.1183/09031936.00196412. Epub 2013 Mar 21. Review.


Neutrophil Intercellular Communication in Acute Lung Injury: Emerging Roles of Microparticles and Gap Junctions.

Dengler V, Downey GP, Tuder RM, Eltzschig HK, Schmidt EP.

Am J Respir Cell Mol Biol. 2013 Mar 14. [Epub ahead of print]


Reply: defining lung injury in animals.

Matute-Bello G, Downey GP.

Am J Respir Cell Mol Biol. 2013 Feb;48(2):267-8. No abstract available.


The yin and yang of cystic fibrosis transmembrane conductance regulator function: implications for chronic lung disease.

Vij N, Downey GP.

Am J Respir Crit Care Med. 2013 Jan 15;187(2):120-2. doi: 10.1164/rccm.201211-2011ED. No abstract available.


Role of β-catenin-regulated CCN matricellular proteins in epithelial repair after inflammatory lung injury.

Zemans RL, McClendon J, Aschner Y, Briones N, Young SK, Lau LF, Kahn M, Downey GP.

Am J Physiol Lung Cell Mol Physiol. 2013 Mar 15;304(6):L415-27. doi: 10.1152/ajplung.00180.2012. Epub 2013 Jan 11.


Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury.

Koeppen M, McNamee EN, Brodsky KS, Aherne CM, Faigle M, Downey GP, Colgan SP, Evans CM, Schwartz DA, Eltzschig HK.

Mucosal Immunol. 2013 Jul;6(4):762-75. doi: 10.1038/mi.2012.114. Epub 2012 Nov 28.


IL-1β enhances cell adhesion to degraded fibronectin.

Rajshankar D, Downey GP, McCulloch CA.

FASEB J. 2012 Nov;26(11):4429-44. doi: 10.1096/fj.12-207381. Epub 2012 Jul 24.


Matrix metalloproteinase induction of Rac1b, a key effector of lung cancer progression.

Stallings-Mann ML, Waldmann J, Zhang Y, Miller E, Gauthier ML, Visscher DW, Downey GP, Radisky ES, Fields AP, Radisky DC.

Sci Transl Med. 2012 Jul 11;4(142):142ra95. doi: 10.1126/scitranslmed.3004062.

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