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Items: 1 to 20 of 33


Regulation of the BMP Signaling-Responsive Transcriptional Network in the Drosophila Embryo.

Deignan L, Pinheiro MT, Sutcliffe C, Saunders A, Wilcockson SG, Zeef LA, Donaldson IJ, Ashe HL.

PLoS Genet. 2016 Jul 5;12(7):e1006164. doi: 10.1371/journal.pgen.1006164. eCollection 2016 Jul.


Hoxa2 selectively enhances Meis binding to change a branchial arch ground state.

Amin S, Donaldson IJ, Zannino DA, Hensman J, Rattray M, Losa M, Spitz F, Ladam F, Sagerström C, Bobola N.

Dev Cell. 2015 Feb 9;32(3):265-77. doi: 10.1016/j.devcel.2014.12.024. Epub 2015 Jan 29.


Sequencing and characterisation of rearrangements in three S. pastorianus strains reveals the presence of chimeric genes and gives evidence of breakpoint reuse.

Hewitt SK, Donaldson IJ, Lovell SC, Delneri D.

PLoS One. 2014 Mar 18;9(3):e92203. doi: 10.1371/journal.pone.0092203. eCollection 2014.


Genome-wide occupancy links Hoxa2 to Wnt-β-catenin signaling in mouse embryonic development.

Donaldson IJ, Amin S, Hensman JJ, Kutejova E, Rattray M, Lawrence N, Hayes A, Ward CM, Bobola N.

Nucleic Acids Res. 2012 May;40(9):3990-4001. doi: 10.1093/nar/gkr1240. Epub 2012 Jan 5.


The forkhead transcription factor FOXK2 promotes AP-1-mediated transcriptional regulation.

Ji Z, Donaldson IJ, Liu J, Hayes A, Zeef LA, Sharrocks AD.

Mol Cell Biol. 2012 Jan;32(2):385-98. doi: 10.1128/MCB.05504-11. Epub 2011 Nov 14. Erratum in: Mol Cell Biol. 2014 May;34(10):1892.


Overlapping promoter targeting by Elk-1 and other divergent ETS-domain transcription factor family members.

Boros J, O'Donnell A, Donaldson IJ, Kasza A, Zeef L, Sharrocks AD.

Nucleic Acids Res. 2009 Dec;37(22):7368-80. doi: 10.1093/nar/gkp804. Epub .


Elucidation of the ELK1 target gene network reveals a role in the coordinate regulation of core components of the gene regulation machinery.

Boros J, Donaldson IJ, O'Donnell A, Odrowaz ZA, Zeef L, Lupien M, Meyer CA, Liu XS, Brown M, Sharrocks AD.

Genome Res. 2009 Nov;19(11):1963-73. doi: 10.1101/gr.093047.109. Epub 2009 Aug 17.


ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling.

Wood AD, Chen E, Donaldson IJ, Hattangadi S, Burke KA, Dawson MA, Miranda-Saavedra D, Lodish HF, Green AR, Göttgens B.

Blood. 2009 Aug 27;114(9):1820-30. doi: 10.1182/blood-2009-02-206573. Epub 2009 Jul 1.


The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development.

Wilson NK, Miranda-Saavedra D, Kinston S, Bonadies N, Foster SD, Calero-Nieto F, Dawson MA, Donaldson IJ, Dumon S, Frampton J, Janky R, Sun XH, Teichmann SA, Bannister AJ, Göttgens B.

Blood. 2009 May 28;113(22):5456-65. doi: 10.1182/blood-2009-01-200048. Epub 2009 Apr 3.


Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors.

Landry JR, Bonadies N, Kinston S, Knezevic K, Wilson NK, Oram SH, Janes M, Piltz S, Hammett M, Carter J, Hamilton T, Donaldson IJ, Lacaud G, Frampton J, Follows G, Kouskoff V, Göttgens B.

Blood. 2009 Jun 4;113(23):5783-92. doi: 10.1182/blood-2008-11-187757. Epub 2009 Jan 26.


A novel mode of enhancer evolution: the Tal1 stem cell enhancer recruited a MIR element to specifically boost its activity.

Smith AM, Sanchez MJ, Follows GA, Kinston S, Donaldson IJ, Green AR, Göttgens B.

Genome Res. 2008 Sep;18(9):1422-32. doi: 10.1101/gr.077008.108. Epub 2008 Aug 7.


ORegAnno: an open-access community-driven resource for regulatory annotation.

Griffith OL, Montgomery SB, Bernier B, Chu B, Kasaian K, Aerts S, Mahony S, Sleumer MC, Bilenky M, Haeussler M, Griffith M, Gallo SM, Giardine B, Hooghe B, Van Loo P, Blanco E, Ticoll A, Lithwick S, Portales-Casamar E, Donaldson IJ, Robertson G, Wadelius C, De Bleser P, Vlieghe D, Halfon MS, Wasserman W, Hardison R, Bergman CM, Jones SJ; Open Regulatory Annotation Consortium.

Nucleic Acids Res. 2008 Jan;36(Database issue):D107-13. Epub 2007 Nov 15.


Inference, validation, and dynamic modeling of transcription networks in multipotent hematopoietic cells.

Soneji S, Huang S, Loose M, Donaldson IJ, Patient R, Göttgens B, Enver T, May G.

Ann N Y Acad Sci. 2007 Jun;1106:30-40. Epub 2007 Apr 18. Review.


The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity.

Pimanda JE, Donaldson IJ, de Bruijn MF, Kinston S, Knezevic K, Huckle L, Piltz S, Landry JR, Green AR, Tannahill D, Göttgens B.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):840-5. Epub 2007 Jan 9.


Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif.

Castro DS, Skowronska-Krawczyk D, Armant O, Donaldson IJ, Parras C, Hunt C, Critchley JA, Nguyen L, Gossler A, Göttgens B, Matter JM, Guillemot F.

Dev Cell. 2006 Dec;11(6):831-44.


CoMoDis: composite motif discovery in mammalian genomes.

Donaldson IJ, Göttgens B.

Nucleic Acids Res. 2007;35(1):e1. Epub 2006 Nov 27.


The paralogous hematopoietic regulators Lyl1 and Scl are coregulated by Ets and GATA factors, but Lyl1 cannot rescue the early Scl-/- phenotype.

Chan WY, Follows GA, Lacaud G, Pimanda JE, Landry JR, Kinston S, Knezevic K, Piltz S, Donaldson IJ, Gambardella L, Sablitzky F, Green AR, Kouskoff V, Göttgens B.

Blood. 2007 Mar 1;109(5):1908-16. Epub 2006 Oct 19.


Identifying gene regulatory elements by genomic microarray mapping of DNaseI hypersensitive sites.

Follows GA, Dhami P, Göttgens B, Bruce AW, Campbell PJ, Dillon SC, Smith AM, Koch C, Donaldson IJ, Scott MA, Dunham I, Janes ME, Vetrie D, Green AR.

Genome Res. 2006 Oct;16(10):1310-9. Epub 2006 Sep 8.


Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication.

Johnson R, Gamblin RJ, Ooi L, Bruce AW, Donaldson IJ, Westhead DR, Wood IC, Jackson RM, Buckley NJ.

Nucleic Acids Res. 2006;34(14):3862-77. Epub 2006 Aug 9.


TFBScluster web server for the identification of mammalian composite regulatory elements.

Donaldson IJ, Göttgens B.

Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W524-8.

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