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Items: 1 to 20 of 145


SOD2 targeted gene editing by CRISPR/Cas9 yields Human cells devoid of MnSOD.

Cramer-Morales K, Heer CD, Mapuskar KA, Domann FE.

Free Radic Biol Med. 2015 Dec;89:379-86. doi: 10.1016/j.freeradbiomed.2015.07.017. Epub 2015 Jul 21.


Disruption of thioredoxin metabolism enhances the toxicity of transforming growth factor β-activated kinase 1 (TAK1) inhibition in KRAS-mutated colon cancer cells.

Hrabe JE, O'Leary BR, Fath MA, Rodman SN, Button AM, Domann FE, Spitz DR, Mezhir JJ.

Redox Biol. 2015 Aug;5:319-27. doi: 10.1016/j.redox.2015.06.004. Epub 2015 Jun 18.


Back to the future: transgenerational transmission of xenobiotic-induced epigenetic remodeling.

Jiménez-Chillarón JC, Nijland MJ, Ascensão AA, Sardão VA, Magalhães J, Hitchler MJ, Domann FE, Oliveira PJ.

Epigenetics. 2015;10(4):259-73. doi: 10.1080/15592294.2015.1020267. Epub 2015 Mar 16. Review.


The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis.

Park JM, Wu T, Cyr AR, Woodfield GW, De Andrade JP, Spanheimer PM, Li T, Sugg SL, Lal G, Domann FE, Zhang W, Weigel RJ.

Oncogene. 2015 Dec 10;34(50):6105-14. doi: 10.1038/onc.2015.59. Epub 2015 Mar 16.


Corrigendum to "Cucurbitacin B Causes Increased Radiation Sensitivity of Human Breast Cancer Cells via G2/M Cell Cycle Arrest".

Duangmano S, Sae-Lim P, Suksamrarn A, Patmasiriwat P, Domann FE.

J Oncol. 2015;2015:486850. doi: 10.1155/2015/486850. Epub 2015 Feb 2.


Ligand-independent activation of aryl hydrocarbon receptor signaling in PCB3-quinone treated HaCaT human keratinocytes.

Xiao W, Son J, Vorrink SU, Domann FE, Goswami PC.

Toxicol Lett. 2015 Mar 18;233(3):258-66. doi: 10.1016/j.toxlet.2015.02.005. Epub 2015 Feb 7.


Loss of SOD3 (EcSOD) Expression Promotes an Aggressive Phenotype in Human Pancreatic Ductal Adenocarcinoma.

O'Leary BR, Fath MA, Bellizzi AM, Hrabe JE, Button AM, Allen BG, Case AJ, Altekruse S, Wagner BA, Buettner GR, Lynch CF, Hernandez BY, Cozen W, Beardsley RA, Keene J, Henry MD, Domann FE, Spitz DR, Mezhir JJ.

Clin Cancer Res. 2015 Apr 1;21(7):1741-51. doi: 10.1158/1078-0432.CCR-14-1959. Epub 2015 Jan 29.


Aberrant CpG methylation of the TFAP2A gene constitutes a mechanism for loss of TFAP2A expression in human metastatic melanoma.

Hallberg AR, Vorrink SU, Hudachek DR, Cramer-Morales K, Milhem MM, Cornell RA, Domann FE.

Epigenetics. 2014 Dec;9(12):1641-7. doi: 10.4161/15592294.2014.988062.


SIRT6 minor allele genotype is associated with >5-year decrease in lifespan in an aged cohort.

TenNapel MJ, Lynch CF, Burns TL, Wallace R, Smith BJ, Button A, Domann FE.

PLoS One. 2014 Dec 26;9(12):e115616. doi: 10.1371/journal.pone.0115616. eCollection 2014.


Succinate dehydrogenase activity regulates PCB3-quinone-induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes.

Xiao W, Sarsour EH, Wagner BA, Doskey CM, Buettner GR, Domann FE, Goswami PC.

Arch Toxicol. 2014 Nov 23. [Epub ahead of print]


Systematic dissection of the mechanisms underlying progesterone receptor downregulation in endometrial cancer.

Yang S, Jia Y, Liu X, Winters C, Wang X, Zhang Y, Devor EJ, Hovey AM, Reyes HD, Xiao X, Xu Y, Dai D, Meng X, Thiel KW, Domann FE, Leslie KK.

Oncotarget. 2014 Oct 30;5(20):9783-97.


Mitochondria, energetics, epigenetics, and cellular responses to stress.

Shaughnessy DT, McAllister K, Worth L, Haugen AC, Meyer JN, Domann FE, Van Houten B, Mostoslavsky R, Bultman SJ, Baccarelli AA, Begley TJ, Sobol RW, Hirschey MD, Ideker T, Santos JH, Copeland WC, Tice RR, Balshaw DM, Tyson FL.

Environ Health Perspect. 2014 Dec;122(12):1271-8. doi: 10.1289/ehp.1408418. Epub 2014 Aug 15. Review.


Epigenetic determinants of CYP1A1 induction by the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB 126).

Vorrink SU, Hudachek DR, Domann FE.

Int J Mol Sci. 2014 Aug 11;15(8):13916-31. doi: 10.3390/ijms150813916.


Retroviral-infection increases tumorigenic potential of MDA-MB-231 breast carcinoma cells by expanding an aldehyde dehydrogenase (ALDH1) positive stem-cell like population.

Wegman-Points LJ, Teoh-Fitzgerald ML, Mao G, Zhu Y, Fath MA, Spitz DR, Domann FE.

Redox Biol. 2014 Jun 24;2:847-54. doi: 10.1016/j.redox.2014.06.006. eCollection 2014.


PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells.

Vorrink SU, Sarsour EH, Olivier AK, Robertson LW, Goswami PC, Domann FE.

Exp Toxicol Pathol. 2014 Oct;66(8):377-82. doi: 10.1016/j.etp.2014.05.005. Epub 2014 Jun 7.


Regulatory crosstalk and interference between the xenobiotic and hypoxia sensing pathways at the AhR-ARNT-HIF1α signaling node.

Vorrink SU, Domann FE.

Chem Biol Interact. 2014 Jul 25;218:82-8. doi: 10.1016/j.cbi.2014.05.001. Epub 2014 May 10. Review.


Mitochondrial calcium uniporter activity is dispensable for MDA-MB-231 breast carcinoma cell survival.

Hall DD, Wu Y, Domann FE, Spitz DR, Anderson ME.

PLoS One. 2014 May 6;9(5):e96866. doi: 10.1371/journal.pone.0096866. eCollection 2014.


Prolyl-hydroxylase 3: Evolving Roles for an Ancient Signaling Protein.

Place TL, Domann FE.

Hypoxia (Auckl). 2013 Oct 1;2013(1):13-17.


Locally targeted delivery of a micron-size radiation therapy source using temperature-sensitive hydrogel.

Kim Y, Seol DR, Mohapatra S, Sunderland JJ, Schultz MK, Domann FE, Lim TH.

Int J Radiat Oncol Biol Phys. 2014 Apr 1;88(5):1142-7. doi: 10.1016/j.ijrobp.2013.12.025. Epub 2014 Feb 1.


Absence of manganese superoxide dismutase delays p53-induced tumor formation.

Case AJ, Domann FE.

Redox Biol. 2014 Jan 13;2:220-3. doi: 10.1016/j.redox.2014.01.001. eCollection 2014.

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