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Results: 1 to 20 of 259

1.

Linking the genetic architecture of cytosine modifications with human complex traits.

Zhang X, Moen EL, Liu C, Mu W, Gamazon ER, Delaney SM, Wing C, Godley LA, Dolan ME, Zhang W.

Hum Mol Genet. 2014 Jun 18. pii: ddu313. [Epub ahead of print]

PMID:
24943591
[PubMed - as supplied by publisher]
2.

Poly-Omic Prediction of Complex Traits: OmicKriging.

Wheeler HE, Aquino-Michaels K, Gamazon ER, Trubetskoy VV, Dolan ME, Huang RS, Cox NJ, Im HK.

Genet Epidemiol. 2014 Jul;38(5):402-15. doi: 10.1002/gepi.21808. Epub 2014 May 2.

PMID:
24799323
[PubMed - in process]
3.

Protein quantitative trait loci identify novel candidates modulating cellular response to chemotherapy.

Stark AL, Hause RJ Jr, Gorsic LK, Antao NN, Wong SS, Chung SH, Gill DF, Im HK, Myers JL, White KP, Jones RB, Dolan ME.

PLoS Genet. 2014 Apr 3;10(4):e1004192. doi: 10.1371/journal.pgen.1004192. eCollection 2014 Apr.

PMID:
24699359
[PubMed - in process]
Free PMC Article
4.

Chemotherapy-induced peripheral neurotoxicity and ototoxicity: new paradigms for translational genomics.

Travis LB, Fossa SD, Sesso HD, Frisina RD, Herrmann DN, Beard CJ, Feldman DR, Pagliaro LC, Miller RC, Vaughn DJ, Einhorn LH, Cox NJ, Dolan ME; Platinum Study Group.

J Natl Cancer Inst. 2014 Mar 12;106(5). pii: dju044. doi: 10.1093/jnci/dju044. Review.

PMID:
24623533
[PubMed - indexed for MEDLINE]
5.

Identification of genetic variants associated with capecitabine-induced hand-foot syndrome through integration of patient and cell line genomic analyses.

Wheeler HE, González-Neira A, Pita G, de la Torre-Montero JC, Alonso R, Lopez-Fernandez LA, Alba E, Martín M, Dolan ME.

Pharmacogenet Genomics. 2014 May;24(5):231-7. doi: 10.1097/FPC.0000000000000037.

PMID:
24595012
[PubMed - in process]
6.

The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide.

Moen EL, Stark AL, Zhang W, Dolan ME, Godley LA.

Mol Cancer Ther. 2014 May;13(5):1334-44. doi: 10.1158/1535-7163.MCT-13-0924. Epub 2014 Feb 25.

PMID:
24568970
[PubMed - in process]
7.

Integrating cell-based and clinical genome-wide studies to identify genetic variants contributing to treatment failure in neuroblastoma patients.

Pinto N, Gamazon ER, Antao N, Myers J, Stark AL, Konkashbaev A, Im HK, Diskin SJ, London WB, Ludeman SM, Maris JM, Cox NJ, Cohn SL, Dolan ME.

Clin Pharmacol Ther. 2014 Jun;95(6):644-52. doi: 10.1038/clpt.2014.37. Epub 2014 Feb 18.

PMID:
24549002
[PubMed - indexed for MEDLINE]
8.

EPS8 inhibition increases cisplatin sensitivity in lung cancer cells.

Gorsic LK, Stark AL, Wheeler HE, Wong SS, Im HK, Dolan ME.

PLoS One. 2013 Dec 19;8(12):e82220. doi: 10.1371/journal.pone.0082220. eCollection 2013.

PMID:
24367505
[PubMed - in process]
Free PMC Article
9.

RRM1 and RRM2 pharmacogenetics: association with phenotypes in HapMap cell lines and acute myeloid leukemia patients.

Cao X, Mitra AK, Pounds S, Crews KR, Gandhi V, Plunkett W, Dolan ME, Hartford C, Raimondi S, Campana D, Downing J, Rubnitz JE, Ribeiro RC, Lamba JK.

Pharmacogenomics. 2013 Sep;14(12):1449-66. doi: 10.2217/pgs.13.131.

PMID:
24024897
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Institutional Profile: University of Chicago Center for Personalized Therapeutics: research, education and implementation science.

Dolan ME, Maitland ML, O'Donnell PH, Nakamura Y, Cox NJ, Ratain MJ.

Pharmacogenomics. 2013 Sep;14(12):1383-7. doi: 10.2217/pgs.13.134.

PMID:
24024891
[PubMed - indexed for MEDLINE]
11.

Cell cycle arrest in a model of colistin nephrotoxicity.

Eadon MT, Hack BK, Alexander JJ, Xu C, Dolan ME, Cunningham PN.

Physiol Genomics. 2013 Oct 1;45(19):877-88. doi: 10.1152/physiolgenomics.00076.2013. Epub 2013 Aug 6.

PMID:
23922129
[PubMed - indexed for MEDLINE]
12.

Genome-wide variation of cytosine modifications between European and African populations and the implications for complex traits.

Moen EL, Zhang X, Mu W, Delaney SM, Wing C, McQuade J, Myers J, Godley LA, Dolan ME, Zhang W.

Genetics. 2013 Aug;194(4):987-96. doi: 10.1534/genetics.113.151381. Epub 2013 Jun 21.

PMID:
23792949
[PubMed - indexed for MEDLINE]
13.

Genetic and epigenetic variants contributing to clofarabine cytotoxicity.

Eadon MT, Wheeler HE, Stark AL, Zhang X, Moen EL, Delaney SM, Im HK, Cunningham PN, Zhang W, Dolan ME.

Hum Mol Genet. 2013 Oct 1;22(19):4007-20. doi: 10.1093/hmg/ddt240. Epub 2013 May 29.

PMID:
23720496
[PubMed - indexed for MEDLINE]
14.

Lymphoblastoid cell lines in pharmacogenomics: how applicable are they to clinical outcomes?

Stark AL, Dolan ME.

Pharmacogenomics. 2013 Apr;14(5):447-50. doi: 10.2217/pgs.13.32. No abstract available.

PMID:
23556440
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients.

Gamazon ER, Lamba JK, Pounds S, Stark AL, Wheeler HE, Cao X, Im HK, Mitra AK, Rubnitz JE, Ribeiro RC, Raimondi S, Campana D, Crews KR, Wong SS, Welsh M, Hulur I, Gorsic L, Hartford CM, Zhang W, Cox NJ, Dolan ME.

Blood. 2013 May 23;121(21):4366-76. doi: 10.1182/blood-2012-10-464149. Epub 2013 Mar 28.

PMID:
23538338
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11.

Bockhorn J, Dalton R, Nwachukwu C, Huang S, Prat A, Yee K, Chang YF, Huo D, Wen Y, Swanson KE, Qiu T, Lu J, Park SY, Dolan ME, Perou CM, Olopade OI, Clarke MF, Greene GL, Liu H.

Nat Commun. 2013;4:1393. doi: 10.1038/ncomms2393.

PMID:
23340433
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Trans-population analysis of genetic mechanisms of ethnic disparities in neuroblastoma survival.

Gamazon ER, Pinto N, Konkashbaev A, Im HK, Diskin SJ, London WB, Maris JM, Dolan ME, Cox NJ, Cohn SL.

J Natl Cancer Inst. 2013 Feb 20;105(4):302-9. doi: 10.1093/jnci/djs503. Epub 2012 Dec 14.

PMID:
23243203
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.

Wheeler HE, Gamazon ER, Wing C, Njiaju UO, Njoku C, Baldwin RM, Owzar K, Jiang C, Watson D, Shterev I, Kubo M, Zembutsu H, Winer EP, Hudis CA, Shulman LN, Nakamura Y, Ratain MJ, Kroetz DL; Cancer and Leukemia Group B, Cox NJ, Dolan ME.

Clin Cancer Res. 2013 Jan 15;19(2):491-9. doi: 10.1158/1078-0432.CCR-12-2618. Epub 2012 Nov 30.

PMID:
23204130
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Pharmacogenomics of chemotherapeutic susceptibility and toxicity.

Moen EL, Godley LA, Zhang W, Dolan ME.

Genome Med. 2012 Nov 30;4(11):90. doi: 10.1186/gm391. eCollection 2012. Review.

PMID:
23199206
[PubMed]
Free PMC Article
20.

Cancer pharmacogenomics: strategies and challenges.

Wheeler HE, Maitland ML, Dolan ME, Cox NJ, Ratain MJ.

Nat Rev Genet. 2013 Jan;14(1):23-34. doi: 10.1038/nrg3352. Epub 2012 Nov 27. Review.

PMID:
23183705
[PubMed - indexed for MEDLINE]
Free PMC Article

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