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Results: 15

1.

The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so.

Kell DB, Dobson PD, Bilsland E, Oliver SG.

Drug Discov Today. 2013 Mar;18(5-6):218-39. doi: 10.1016/j.drudis.2012.11.008. Epub 2012 Nov 30.

PMID:
23207804
[PubMed - indexed for MEDLINE]
2.

Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast.

Lanthaler K, Bilsland E, Dobson PD, Moss HJ, Pir P, Kell DB, Oliver SG.

BMC Biol. 2011 Oct 24;9:70. doi: 10.1186/1741-7007-9-70.

PMID:
22023736
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Mining metabolites: extracting the yeast metabolome from the literature.

Nobata C, Dobson PD, Iqbal SA, Mendes P, Tsujii J, Kell DB, Ananiadou S.

Metabolomics. 2011 Mar;7(1):94-101. Epub 2010 Oct 31.

PMID:
21687783
[PubMed]
Free PMC Article
4.

Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only.

Kell DB, Dobson PD, Oliver SG.

Drug Discov Today. 2011 Aug;16(15-16):704-14. doi: 10.1016/j.drudis.2011.05.010. Epub 2011 May 23.

PMID:
21624498
[PubMed - indexed for MEDLINE]
5.

Further developments towards a genome-scale metabolic model of yeast.

Dobson PD, Smallbone K, Jameson D, Simeonidis E, Lanthaler K, Pir P, Lu C, Swainston N, Dunn WB, Fisher P, Hull D, Brown M, Oshota O, Stanford NJ, Kell DB, King RD, Oliver SG, Stevens RD, Mendes P.

BMC Syst Biol. 2010 Oct 28;4:145. doi: 10.1186/1752-0509-4-145.

PMID:
21029416
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Implications of the dominant role of transporters in drug uptake by cells.

Dobson PD, Lanthaler K, Oliver SG, Kell DB.

Curr Top Med Chem. 2009;9(2):163-81. Review.

PMID:
19200003
[PubMed - indexed for MEDLINE]
7.

'Metabolite-likeness' as a criterion in the design and selection of pharmaceutical drug libraries.

Dobson PD, Patel Y, Kell DB.

Drug Discov Today. 2009 Jan;14(1-2):31-40. doi: 10.1016/j.drudis.2008.10.011. Epub 2008 Dec 26. Review.

PMID:
19049901
[PubMed - indexed for MEDLINE]
8.

Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?

Dobson PD, Kell DB.

Nat Rev Drug Discov. 2008 Mar;7(3):205-20. doi: 10.1038/nrd2438. Review.

PMID:
18309312
[PubMed - indexed for MEDLINE]
9.

The band assignment parser: a tool to identify band assignments in research publications.

Dobson PD, Blanch EW.

Appl Spectrosc. 2007 Mar;61(3):346-7. No abstract available.

PMID:
17389077
[PubMed]
10.

A simple approach to normalization for spectroscopic data mining.

Dobson PD, Doig AJ, Blanch EW.

Appl Spectrosc. 2005 Apr;59(4):542-4. No abstract available.

PMID:
15901341
[PubMed - indexed for MEDLINE]
11.

Predicting enzyme class from protein structure without alignments.

Dobson PD, Doig AJ.

J Mol Biol. 2005 Jan 7;345(1):187-99.

PMID:
15567421
[PubMed - indexed for MEDLINE]
12.

Prediction of protein function in the absence of significant sequence similarity.

Dobson PD, Cai YD, Stapley BJ, Doig AJ.

Curr Med Chem. 2004 Aug;11(16):2135-42. Review.

PMID:
15279553
[PubMed - indexed for MEDLINE]
13.

Length preferences and periodicity in beta-strands. Antiparallel edge beta-sheets are more likely to finish in non-hydrogen bonded rings.

Penel S, Morrison RG, Dobson PD, Mortishire-Smith RJ, Doig AJ.

Protein Eng. 2003 Dec;16(12):957-61.

PMID:
14983075
[PubMed - indexed for MEDLINE]
Free Article
14.

Distinguishing enzyme structures from non-enzymes without alignments.

Dobson PD, Doig AJ.

J Mol Biol. 2003 Jul 18;330(4):771-83.

PMID:
12850146
[PubMed - indexed for MEDLINE]
15.

New technologies for amperometric biosensors.

Boutelle MG, Allen H, Hill O, Berners M, John R, Dobson PD, Leigh P.

J Mol Recognit. 1996 Sep-Dec;9(5-6):664-71.

PMID:
9174954
[PubMed - indexed for MEDLINE]

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