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Systemic sclerosis and localized scleroderma-current concepts and novel targets for therapy.

Distler O, Cozzio A.

Semin Immunopathol. 2015 Nov 17. [Epub ahead of print]


Efficient therapy of ischaemic lesions with VEGF121-fibrin in an animal model of systemic sclerosis.

Allipour Birgani S, Mailänder M, Wasle I, Dietrich H, Gruber J, Distler O, Sgonc R.

Ann Rheum Dis. 2015 Sep 11. pii: annrheumdis-2015-207548. doi: 10.1136/annrheumdis-2015-207548. [Epub ahead of print]


Autopsy versus clinical findings in patients with systemic sclerosis in a case series from patients of the EUSTAR database.

Sandmeier B, Jäger VK, Nagy G, Carreira PE, Tzankov A, Widuchowska M, Antic M, Distler O, Reichert H, Distler JH, Walker UA, Hügle T.

Clin Exp Rheumatol. 2015 Jul-Aug;33(4 Suppl 91):S75-9. Epub 2015 Sep 1.


Type 2 innate lymphoid cell counts are increased in patients with systemic sclerosis and correlate with the extent of fibrosis.

Wohlfahrt T, Usherenko S, Englbrecht M, Dees C, Weber S, Beyer C, Gelse K, Distler O, Schett G, Distler JH, Ramming A.

Ann Rheum Dis. 2015 Sep 2. pii: annrheumdis-2015-207388. doi: 10.1136/annrheumdis-2015-207388. [Epub ahead of print]


Brief Report: Pulmonary Function Tests: High Rate of False-Negative Results in the Early Detection and Screening of Scleroderma-Related Interstitial Lung Disease.

Suliman YA, Dobrota R, Huscher D, Nguyen-Kim TD, Maurer B, Jordan S, Speich R, Frauenfelder T, Distler O.

Arthritis Rheumatol. 2015 Dec;67(12):3256-61. doi: 10.1002/art.39405.


Incidence and predictors of cutaneous manifestations during the early course of systemic sclerosis: a 10-year longitudinal study from the EUSTAR database.

Wirz EG, Jaeger VK, Allanore Y, Riemekasten G, Hachulla E, Distler O, Airò P, Carreira PE, Tikly M, Vettori S, Balbir Gurman A, Damjanov N, Müller-Ladner U, Distler J, Li M, Häusermann P, Walker UA; EUSTAR coauthors.

Ann Rheum Dis. 2015 Jul 31. pii: annrheumdis-2015-207271. doi: 10.1136/annrheumdis-2015-207271. [Epub ahead of print]


Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis.

Huang J, Beyer C, Palumbo-Zerr K, Zhang Y, Ramming A, Distler A, Gelse K, Distler O, Schett G, Wollin L, Distler JH.

Ann Rheum Dis. 2015 Apr 9. pii: annrheumdis-2014-207109. doi: 10.1136/annrheumdis-2014-207109. [Epub ahead of print]


Stimulators of soluble guanylate cyclase (sGC) inhibit experimental skin fibrosis of different aetiologies.

Dees C, Beyer C, Distler A, Soare A, Zhang Y, Palumbo-Zerr K, Distler O, Schett G, Sandner P, Distler JH.

Ann Rheum Dis. 2015 Aug;74(8):1621-5. doi: 10.1136/annrheumdis-2014-206809. Epub 2015 Mar 27.


[Common German language nomenclature for systemic sclerosis].

Aringer M, Müller-Ladner U, Burkhardt H, Distler JH, Distler O, Graninger WB, Günther C, Hunzelmann N, Kiener H, Sticherling M, Sunderkötter C, Walker UA, Riemekasten G.

Z Rheumatol. 2015 Mar;74(2):100-3. doi: 10.1007/s00393-014-1550-5. German.


Performance of the new ACR/EULAR classification criteria for systemic sclerosis in clinical practice.

Jordan S, Maurer B, Toniolo M, Michel B, Distler O.

Rheumatology (Oxford). 2015 Aug;54(8):1454-8. doi: 10.1093/rheumatology/keu530. Epub 2015 Mar 11.


Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis.

Tomcik M, Palumbo-Zerr K, Zerr P, Sumova B, Avouac J, Dees C, Distler A, Becvar R, Distler O, Schett G, Senolt L, Distler JH.

Ann Rheum Dis. 2015 Jan 20. pii: annrheumdis-2014-206234. doi: 10.1136/annrheumdis-2014-206234. [Epub ahead of print]


Value of systolic pulmonary arterial pressure as a prognostic factor of death in the systemic sclerosis EUSTAR population.

Hachulla E, Clerson P, Airò P, Cuomo G, Allanore Y, Caramaschi P, Rosato E, Carreira PE, Riccieri V, Sarraco M, Denton CP, Riemekasten G, Pozzi MR, Zeni S, Mihai CM, Ullman S, Distler O, Rednic S, Smith V, Walker UA, Matucci-Cerinic M, Müller-Ladner U, Launay D; EUSTAR co-workers.

Rheumatology (Oxford). 2015 Jul;54(7):1262-9. doi: 10.1093/rheumatology/keu450. Epub 2015 Jan 17.


Activating transcription factor 3 regulates canonical TGFβ signalling in systemic sclerosis.

Mallano T, Palumbo-Zerr K, Zerr P, Ramming A, Zeller B, Beyer C, Dees C, Huang J, Hai T, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2015 Jan 14. pii: annrheumdis-2014-206214. doi: 10.1136/annrheumdis-2014-206214. [Epub ahead of print]


Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis.

Palumbo-Zerr K, Zerr P, Distler A, Fliehr J, Mancuso R, Huang J, Mielenz D, Tomcik M, Fürnrohr BG, Scholtysek C, Dees C, Beyer C, Krönke G, Metzger D, Distler O, Schett G, Distler JH.

Nat Med. 2015 Feb;21(2):150-8. doi: 10.1038/nm.3777. Epub 2015 Jan 12.


Personal factors in systemic sclerosis and their coverage by patient-reported outcome measures. A multicentre European qualitative study and literature review.

Mattsson M, Boström C, Mihai C, Stöcker J, Geyh S, Stummvoll G, Gard G, Möller B, Hesselstrand R, Sandqvist G, Draghicescu O, Gherghe AM, Voicu M, Distler O, Smolen JS, Stamm TA.

Eur J Phys Rehabil Med. 2015 Aug;51(4):405-21. Epub 2015 Jan 9.


Systemic sclerosis in 2014: Advances in cohort enrichment shape future of trial design.

Allanore Y, Distler O.

Nat Rev Rheumatol. 2015 Feb;11(2):72-4. doi: 10.1038/nrrheum.2014.222. Epub 2015 Jan 6.


Borderline pulmonary arterial pressure in systemic sclerosis patients: a post-hoc analysis of the DETECT study.

Visovatti SH, Distler O, Coghlan JG, Denton CP, Grünig E, Bonderman D, Müller-Ladner U, Pope JE, Vonk MC, Seibold JR, Torres-Martin JV, Doelberg M, Chadha-Boreham H, Rosenberg DM, McLaughlin VV, Khanna D.

Arthritis Res Ther. 2014 Dec 10;16(6):493. doi: 10.1186/s13075-014-0493-1.


Downregulation of miR-193b in systemic sclerosis regulates the proliferative vasculopathy by urokinase-type plasminogen activator expression.

Iwamoto N, Vettori S, Maurer B, Brock M, Pachera E, Jüngel A, Calcagni M, Gay RE, Whitfield ML, Distler JH, Gay S, Distler O.

Ann Rheum Dis. 2014 Nov 10. pii: annrheumdis-2014-205326. doi: 10.1136/annrheumdis-2014-205326. [Epub ahead of print]


Cardiomyopathy in murine models of systemic sclerosis.

Venalis P, Kumánovics G, Schulze-Koops H, Distler A, Dees C, Zerr P, Palumbo-Zerr K, Czirják L, Mackevic Z, Lundberg IE, Distler O, Schett G, Distler JH.

Arthritis Rheumatol. 2015 Feb;67(2):508-16. doi: 10.1002/art.38942.


A gender gap in primary and secondary heart dysfunctions in systemic sclerosis: a EUSTAR prospective study.

Elhai M, Avouac J, Walker UA, Matucci-Cerinic M, Riemekasten G, Airò P, Hachulla E, Valentini G, Carreira PE, Cozzi F, Balbir Gurman A, Braun-Moscovici Y, Damjanov N, Ananieva LP, Scorza R, Jimenez S, Busquets J, Li M, Müller-Ladner U, Kahan A, Distler O, Allanore Y; EUSTAR co-authors; EUSTAR co-authors.

Ann Rheum Dis. 2014 Oct 23. pii: annrheumdis-2014-206386. doi: 10.1136/annrheumdis-2014-206386. [Epub ahead of print]

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