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Results: 1 to 20 of 241

1.

Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis.

Huang J, Beyer C, Palumbo-Zerr K, Zhang Y, Ramming A, Distler A, Gelse K, Distler O, Schett G, Wollin L, Distler JH.

Ann Rheum Dis. 2015 Apr 9. pii: annrheumdis-2014-207109. doi: 10.1136/annrheumdis-2014-207109. [Epub ahead of print]

PMID:
25858641
2.

Stimulators of soluble guanylate cyclase (sGC) inhibit experimental skin fibrosis of different aetiologies.

Dees C, Beyer C, Distler A, Soare A, Zhang Y, Palumbo-Zerr K, Distler O, Schett G, Sandner P, Distler JH.

Ann Rheum Dis. 2015 Mar 27. pii: annrheumdis-2014-206809. doi: 10.1136/annrheumdis-2014-206809. [Epub ahead of print]

PMID:
25817717
3.

[Common German language nomenclature for systemic sclerosis].

Aringer M, Müller-Ladner U, Burkhardt H, Distler JH, Distler O, Graninger WB, Günther C, Hunzelmann N, Kiener H, Sticherling M, Sunderkötter C, Walker UA, Riemekasten G.

Z Rheumatol. 2015 Mar;74(2):100-3. doi: 10.1007/s00393-014-1550-5. German.

PMID:
25805510
4.

Performance of the new ACR/EULAR classification criteria for systemic sclerosis in clinical practice.

Jordan S, Maurer B, Toniolo M, Michel B, Distler O.

Rheumatology (Oxford). 2015 Mar 11. pii: keu530. [Epub ahead of print]

PMID:
25762528
5.

Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis.

Tomcik M, Palumbo-Zerr K, Zerr P, Sumova B, Avouac J, Dees C, Distler A, Becvar R, Distler O, Schett G, Senolt L, Distler JH.

Ann Rheum Dis. 2015 Jan 20. pii: annrheumdis-2014-206234. doi: 10.1136/annrheumdis-2014-206234. [Epub ahead of print]

PMID:
25603829
6.

Value of systolic pulmonary arterial pressure as a prognostic factor of death in the systemic sclerosis EUSTAR population.

Hachulla E, Clerson P, Airò P, Cuomo G, Allanore Y, Caramaschi P, Rosato E, Carreira PE, Riccieri V, Sarraco M, Denton CP, Riemekasten G, Pozzi MR, Zeni S, Mihai CM, Ullman S, Distler O, Rednic S, Smith V, Walker UA, Matucci-Cerinic M, Müller-Ladner U, Launay D; on behalf of the EUSTAR co-workers.

Rheumatology (Oxford). 2015 Jan 17. pii: keu450. [Epub ahead of print]

7.

Activating transcription factor 3 regulates canonical TGFβ signalling in systemic sclerosis.

Mallano T, Palumbo-Zerr K, Zerr P, Ramming A, Zeller B, Beyer C, Dees C, Huang J, Hai T, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2015 Jan 14. pii: annrheumdis-2014-206214. doi: 10.1136/annrheumdis-2014-206214. [Epub ahead of print]

PMID:
25589515
8.

Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis.

Palumbo-Zerr K, Zerr P, Distler A, Fliehr J, Mancuso R, Huang J, Mielenz D, Tomcik M, Fürnrohr BG, Scholtysek C, Dees C, Beyer C, Krönke G, Metzger D, Distler O, Schett G, Distler JH.

Nat Med. 2015 Feb;21(2):150-8. doi: 10.1038/nm.3777. Epub 2015 Jan 12.

PMID:
25581517
9.

Personal factors in systemic sclerosis and their coverage by patient-reported outcome measures: A multicentre European qualitative study and literature review.

Mattsson M, Boström C, Mihai C, Stöcker J, Geyh S, Stummvoll G, Gard G, Möller B, Hesselstrand R, Sandqvist G, Draghicescu O, Gherghe AM, Voicu M, Distler O, Smolen JS, Stamm T.

Eur J Phys Rehabil Med. 2015 Jan 9. [Epub ahead of print]

10.

Systemic sclerosis in 2014: Advances in cohort enrichment shape future of trial design.

Allanore Y, Distler O.

Nat Rev Rheumatol. 2015 Feb;11(2):72-4. doi: 10.1038/nrrheum.2014.222. Epub 2015 Jan 6.

PMID:
25561368
11.

Borderline pulmonary arterial pressure in systemic sclerosis patients: a post-hoc analysis of the DETECT study.

Visovatti SH, Distler O, Coghlan JG, Denton CP, Grünig E, Bonderman D, Müller-Ladner U, Pope JE, Vonk MC, Seibold JR, Torres-Martin JV, Doelberg M, Chadha-Boreham H, Rosenberg DM, McLaughlin VV, Khanna D.

Arthritis Res Ther. 2014 Dec 10;16(6):493. doi: 10.1186/s13075-014-0493-1.

12.

Downregulation of miR-193b in systemic sclerosis regulates the proliferative vasculopathy by urokinase-type plasminogen activator expression.

Iwamoto N, Vettori S, Maurer B, Brock M, Pachera E, Jüngel A, Calcagni M, Gay RE, Whitfield ML, Distler JH, Gay S, Distler O.

Ann Rheum Dis. 2014 Nov 10. pii: annrheumdis-2014-205326. doi: 10.1136/annrheumdis-2014-205326. [Epub ahead of print]

PMID:
25384965
13.

Cardiomyopathy in murine models of systemic sclerosis.

Venalis P, Kumánovics G, Schulze-Koops H, Distler A, Dees C, Zerr P, Palumbo-Zerr K, Czirják L, Mackevic Z, Lundberg IE, Distler O, Schett G, Distler JH.

Arthritis Rheumatol. 2015 Feb;67(2):508-16. doi: 10.1002/art.38942.

PMID:
25371068
14.

A gender gap in primary and secondary heart dysfunctions in systemic sclerosis: a EUSTAR prospective study.

Elhai M, Avouac J, Walker UA, Matucci-Cerinic M, Riemekasten G, Airò P, Hachulla E, Valentini G, Carreira PE, Cozzi F, Balbir Gurman A, Braun-Moscovici Y, Damjanov N, Ananieva LP, Scorza R, Jimenez S, Busquets J, Li M, Müller-Ladner U, Kahan A, Distler O, Allanore Y; EUSTAR co-authors; EUSTAR co-authors.

Ann Rheum Dis. 2014 Oct 23. pii: annrheumdis-2014-206386. doi: 10.1136/annrheumdis-2014-206386. [Epub ahead of print]

PMID:
25342760
15.

Screening for interstitial lung disease in systemic sclerosis: performance of high-resolution CT with limited number of slices: a prospective study.

Frauenfelder T, Winklehner A, Nguyen TD, Dobrota R, Baumueller S, Maurer B, Distler O.

Ann Rheum Dis. 2014 Dec;73(12):2069-73. doi: 10.1136/annrheumdis-2014-205637. Epub 2014 Sep 30.

PMID:
25269829
16.

Oxidative DNA damage induces the ATM-mediated transcriptional suppression of the Wnt inhibitor WIF-1 in systemic sclerosis and fibrosis.

Svegliati S, Marrone G, Pezone A, Spadoni T, Grieco A, Moroncini G, Grieco D, Vinciguerra M, Agnese S, Jüngel A, Distler O, Musti AM, Gabrielli A, Avvedimento EV.

Sci Signal. 2014 Sep 2;7(341):ra84. doi: 10.1126/scisignal.2004592.

PMID:
25185156
17.

Sirt1 regulates canonical TGF-β signalling to control fibroblast activation and tissue fibrosis.

Zerr P, Palumbo-Zerr K, Huang J, Tomcik M, Sumova B, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2014 Sep 1. pii: annrheumdis-2014-205740. doi: 10.1136/annrheumdis-2014-205740. [Epub ahead of print]

PMID:
25180292
18.

The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis.

Avouac J, Palumbo-Zerr K, Ruzehaji N, Tomcik M, Zerr P, Dees C, Distler A, Beyer C, Schneider H, Distler O, Schett G, Allanore Y, Distler JH.

Arthritis Rheumatol. 2014 Nov;66(11):3140-50. doi: 10.1002/art.38819.

PMID:
25155144
19.

Twenty-two points to consider for clinical trials in systemic sclerosis, based on EULAR standards.

Khanna D, Furst DE, Allanore Y, Bae S, Bodukam V, Clements PJ, Cutolo M, Czirjak L, Denton CP, Distler O, Walker UA, Matucci-Cerinic M, Müller-Ladner U, Seibold JR, Singh M, Tyndall A.

Rheumatology (Oxford). 2015 Jan;54(1):144-51. doi: 10.1093/rheumatology/keu288. Epub 2014 Aug 13. Review.

PMID:
25125594
20.

Prediction of worsening of skin fibrosis in patients with diffuse cutaneous systemic sclerosis using the EUSTAR database.

Maurer B, Graf N, Michel BA, Müller-Ladner U, Czirják L, Denton CP, Tyndall A, Metzig C, Lanius V, Khanna D, Distler O; EUSTAR co-authors.

Ann Rheum Dis. 2015 Jun;74(6):1124-31. doi: 10.1136/annrheumdis-2014-205226. Epub 2014 Jun 30.

PMID:
24981642
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