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Results: 1 to 20 of 46

1.

Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery.

Murphy AK, Fitzgerald M, Ro T, Kim JH, Rabinowitsch AI, Chowdhury D, Schildkraut CL, Borowiec JA.

J Cell Biol. 2014 Aug 18;206(4):493-507. doi: 10.1083/jcb.201404111. Epub 2014 Aug 11.

PMID:
25113031
[PubMed - in process]
2.

A genome-wide miRNA screen revealed miR-603 as a MGMT-regulating miRNA in glioblastomas.

Kushwaha D, Ramakrishnan V, Ng K, Steed T, Nguyen T, Futalan D, Akers JC, Sarkaria J, Jiang T, Chowdhury D, Carter BS, Chen CC.

Oncotarget. 2014 Jun 30;5(12):4026-39.

PMID:
24994119
[PubMed - in process]
Free Article
3.

MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability.

Choi YE, Pan Y, Park E, Konstantinopoulos P, De S, D'Andrea A, Chowdhury D.

Elife. 2014 Apr 30;3:e02445. doi: 10.7554/eLife.02445.

PMID:
24843000
[PubMed]
Free PMC Article
4.

KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G₁-phase lymphocytes.

Tubbs AT, Dorsett Y, Chan E, Helmink B, Lee BS, Hung P, George R, Bredemeyer AL, Mittal A, Pappu RV, Chowdhury D, Mosammaparast N, Krangel MS, Sleckman BP.

Mol Cell Biol. 2014 Aug;34(15):2811-21. doi: 10.1128/MCB.00441-14. Epub 2014 May 19.

PMID:
24842905
[PubMed - in process]
5.

Sublethal concentrations of 17-AAG suppress homologous recombination DNA repair and enhance sensitivity to carboplatin and olaparib in HR proficient ovarian cancer cells.

Choi YE, Battelli C, Watson J, Liu J, Curtis J, Morse AN, Matulonis UA, Chowdhury D, Konstantinopoulos PA.

Oncotarget. 2014 May 15;5(9):2678-87.

PMID:
24798692
[PubMed - in process]
Free PMC Article
6.

Distinct phosphatases antagonize the p53 response in different phases of the cell cycle.

Shaltiel IA, Aprelia M, Saurin AT, Chowdhury D, Kops GJ, Voest EE, Medema RH.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7313-8. doi: 10.1073/pnas.1322021111. Epub 2014 Apr 7.

PMID:
24711418
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Dephosphorylation enables the recruitment of 53BP1 to double-strand DNA breaks.

Lee DH, Acharya SS, Kwon M, Drane P, Guan Y, Adelmant G, Kalev P, Shah J, Pellman D, Marto JA, Chowdhury D.

Mol Cell. 2014 May 8;54(3):512-25. doi: 10.1016/j.molcel.2014.03.020. Epub 2014 Apr 3.

PMID:
24703952
[PubMed - indexed for MEDLINE]
8.

EGFR-mediated chromatin condensation protects KRAS-mutant cancer cells against ionizing radiation.

Wang M, Kern AM, Hülskötter M, Greninger P, Singh A, Pan Y, Chowdhury D, Krause M, Baumann M, Benes CH, Efstathiou JA, Settleman J, Willers H.

Cancer Res. 2014 May 15;74(10):2825-34. doi: 10.1158/0008-5472.CAN-13-3157. Epub 2014 Mar 19.

PMID:
24648348
[PubMed - indexed for MEDLINE]
9.

Association of microRNAs and pathologic response to preoperative chemotherapy in triple negative breast cancer: preliminary report.

Kolacinska A, Morawiec J, Fendler W, Malachowska B, Morawiec Z, Szemraj J, Pawlowska Z, Chowdhury D, Choi YE, Kubiak R, Pakula L, Zawlik I.

Mol Biol Rep. 2014 May;41(5):2851-7. doi: 10.1007/s11033-014-3140-7. Epub 2014 Jan 29.

PMID:
24469723
[PubMed - in process]
Free PMC Article
10.

A p21-ZEB1 complex inhibits epithelial-mesenchymal transition through the microRNA 183-96-182 cluster.

Li XL, Hara T, Choi Y, Subramanian M, Francis P, Bilke S, Walker RL, Pineda M, Zhu Y, Yang Y, Luo J, Wakefield LM, Brabletz T, Park BH, Sharma S, Chowdhury D, Meltzer PS, Lal A.

Mol Cell Biol. 2014 Feb;34(3):533-50. doi: 10.1128/MCB.01043-13. Epub 2013 Nov 25.

PMID:
24277930
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance.

Johnson N, Johnson SF, Yao W, Li YC, Choi YE, Bernhardy AJ, Wang Y, Capelletti M, Sarosiek KA, Moreau LA, Chowdhury D, Wickramanayake A, Harrell MI, Liu JF, D'Andrea AD, Miron A, Swisher EM, Shapiro GI.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17041-6. doi: 10.1073/pnas.1305170110. Epub 2013 Oct 1.

PMID:
24085845
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Charity begins at home: non-coding RNA functions in DNA repair.

Chowdhury D, Choi YE, Brault ME.

Nat Rev Mol Cell Biol. 2013 Mar;14(3):181-9. doi: 10.1038/nrm3523. Epub 2013 Feb 6.

PMID:
23385724
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Inhibition of non-homologous end joining repair impairs pancreatic cancer growth and enhances radiation response.

Li YH, Wang X, Pan Y, Lee DH, Chowdhury D, Kimmelman AC.

PLoS One. 2012;7(6):e39588. doi: 10.1371/journal.pone.0039588. Epub 2012 Jun 18.

PMID:
22724027
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer.

Benassi B, Flavin R, Marchionni L, Zanata S, Pan Y, Chowdhury D, Marani M, Strano S, Muti P, Blandino G, Loda M.

Cancer Discov. 2012 Mar;2(3):236-47. doi: 10.1158/2159-8290.CD-11-0219. Epub 2012 Jan 5.

PMID:
22585994
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Phosphoproteomic analysis reveals that PP4 dephosphorylates KAP-1 impacting the DNA damage response.

Lee DH, Goodarzi AA, Adelmant GO, Pan Y, Jeggo PA, Marto JA, Chowdhury D.

EMBO J. 2012 May 16;31(10):2403-15. doi: 10.1038/emboj.2012.86. Epub 2012 Apr 10.

PMID:
22491012
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

DNA breaks and chromosome pulverization from errors in mitosis.

Crasta K, Ganem NJ, Dagher R, Lantermann AB, Ivanova EV, Pan Y, Nezi L, Protopopov A, Chowdhury D, Pellman D.

Nature. 2012 Jan 18;482(7383):53-8. doi: 10.1038/nature10802.

PMID:
22258507
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

What goes on must come off: phosphatases gate-crash the DNA damage response.

Lee DH, Chowdhury D.

Trends Biochem Sci. 2011 Nov;36(11):569-77. doi: 10.1016/j.tibs.2011.08.007. Epub 2011 Sep 18. Review.

PMID:
21930385
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Translational control of TOP2A influences doxorubicin efficacy.

Srikantan S, Abdelmohsen K, Lee EK, Tominaga K, Subaran SS, Kuwano Y, Kulshrestha R, Panchakshari R, Kim HH, Yang X, Martindale JL, Marasa BS, Kim MM, Wersto RP, Indig FE, Chowdhury D, Gorospe M.

Mol Cell Biol. 2011 Sep;31(18):3790-801. doi: 10.1128/MCB.05639-11. Epub 2011 Jul 18.

PMID:
21768308
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Personalized therapy for urothelial cancer: review of the clinical evidence.

Guancial EA, Chowdhury D, Rosenberg JE.

Clin Investig (Lond). 2011 Apr;1(4):546-555.

PMID:
22754656
[PubMed]
Free PMC Article
20.

miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors.

Moskwa P, Buffa FM, Pan Y, Panchakshari R, Gottipati P, Muschel RJ, Beech J, Kulshrestha R, Abdelmohsen K, Weinstock DM, Gorospe M, Harris AL, Helleday T, Chowdhury D.

Mol Cell. 2011 Jan 21;41(2):210-20. doi: 10.1016/j.molcel.2010.12.005. Epub 2010 Dec 30. Erratum in: Mol Cell. 2014 Jan 9;53(1):162-3.

PMID:
21195000
[PubMed - indexed for MEDLINE]
Free PMC Article

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