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γδ T cell-based anticancer immunotherapy: progress and possibilities.

Meraviglia S, Lo Presti E, Dieli F, Stassi G.

Immunotherapy. 2015 Sep;7(9):949-51. doi: 10.2217/imt.15.68. Epub 2015 Aug 27. No abstract available.


Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines.

Smith SG, Smits K, Joosten SA, van Meijgaarden KE, Satti I, Fletcher HA, Caccamo N, Dieli F, Mascart F, McShane H, Dockrell HM, Ottenhoff TH; TBVI TB Biomarker Working Group.

PLoS One. 2015 Sep 14;10(9):e0138042. doi: 10.1371/journal.pone.0138042. eCollection 2015.


A Risk Score Derived from the Analysis of a Cluster of 27 Serum Inflammatory Cytokines to Predict Long Term Outcome in Patients with Acute Myocardial Infarction: a Pilot Study.

Novo G, Bellia C, Fiore M, Bonomo V, Pugliesi M, Giovino M, Sasso BL, Meraviglia S, Assennato P, Novo S, Dieli F, Ciaccio M.

Ann Clin Lab Sci. 2015 Summer;45(4):382-90.


CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA.

Conigliaro A, Costa V, Lo Dico A, Saieva L, Buccheri S, Dieli F, Manno M, Raccosta S, Mancone C, Tripodi M, De Leo G, Alessandro R.

Mol Cancer. 2015 Aug 14;14:155. doi: 10.1186/s12943-015-0426-x.


Potential involvement of IL-9 and Th9 cells in the pathogenesis of rheumatoid arthritis.

Ciccia F, Guggino G, Rizzo A, Manzo A, Vitolo B, La Manna MP, Giardina G, Sireci G, Dieli F, Montecucco CM, Alessandro R, Triolo G.

Rheumatology (Oxford). 2015 Dec;54(12):2264-72. doi: 10.1093/rheumatology/kev252. Epub 2015 Jul 15.


Granzyme A as a potential biomarker of Mycobacterium tuberculosis infection and disease.

Guggino G, Orlando V, Cutrera S, La Manna MP, Di Liberto D, Vanini V, Petruccioli E, Dieli F, Goletti D, Caccamo N.

Immunol Lett. 2015 Aug;166(2):87-91. doi: 10.1016/j.imlet.2015.05.019. Epub 2015 Jun 5.


Interleukin (IL)-22 receptor 1 is over-expressed in primary Sjogren's syndrome and Sjögren-associated non-Hodgkin lymphomas and is regulated by IL-18.

Ciccia F, Guggino G, Rizzo A, Bombardieri M, Raimondo S, Carubbi F, Cannizzaro A, Sireci G, Dieli F, Campisi G, Giacomelli R, Cipriani P, De Leo G, Alessandro R, Triolo G.

Clin Exp Immunol. 2015 Aug;181(2):219-29. doi: 10.1111/cei.12643. Epub 2015 Jun 3.


Invariant natural killer T cells treated with rapamycin or transforming growth factor-β acquire a regulatory function and suppress T effector lymphocytes.

Guggino G, Scottà C, Lombardi G, Dieli F, Sireci G.

Cell Mol Immunol. 2014 Apr 6. doi: 10.1038/cmi.2015.20. [Epub ahead of print] No abstract available.


Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human T-cell subset.

van Meijgaarden KE, Haks MC, Caccamo N, Dieli F, Ottenhoff TH, Joosten SA.

PLoS Pathog. 2015 Mar 24;11(3):e1004671. doi: 10.1371/journal.ppat.1004671. eCollection 2015 Mar.


Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines.

Caccamo N, Pietra G, Sullivan LC, Brooks AG, Prezzemolo T, La Manna MP, Di Liberto D, Joosten SA, van Meijgaarden KE, Di Carlo P, Titone L, Moretta L, Mingari MC, Ottenhoff TH, Dieli F.

Eur J Immunol. 2015 Apr;45(4):1069-81. doi: 10.1002/eji.201445193. Epub 2015 Feb 17.


Tumor-Infiltrating γδ T Lymphocytes: Pathogenic Role, Clinical Significance, and Differential Programing in the Tumor Microenvironment.

Lo Presti E, Dieli F, Meraviglia S.

Front Immunol. 2014 Nov 24;5:607. doi: 10.3389/fimmu.2014.00607. eCollection 2014. Review.


Editorial: activation, functions, and generation of immunological memory in γδ T lymphocytes: lessons from nonhuman primates.

Dieli F, Mavilio D.

J Leukoc Biol. 2014 Dec;96(6):948-50. doi: 10.1189/jlb.4CE0714-364R. No abstract available.


γδ T cells as a potential tool in colon cancer immunotherapy.

Ramutton T, Buccheri S, Dieli F, Todaro M, Stassi G, Meraviglia S.

Immunotherapy. 2014;6(9):989-99. doi: 10.2217/imt.14.59. Review.


Vγ9 Vδ2 T lymphocytes activation as a novel approach to test efficacy of different bisphosphonates.

Rini GB, Sprini D, Migliaccio S, Basili S, Strollo R, Dieli F, Napoli N.

Endocrine. 2015 Feb;48(1):346-8. doi: 10.1007/s12020-014-0303-1. Epub 2014 Aug 6. No abstract available.


Functional Signatures of Human CD4 and CD8 T Cell Responses to Mycobacterium tuberculosis.

Prezzemolo T, Guggino G, La Manna MP, Di Liberto D, Dieli F, Caccamo N.

Front Immunol. 2014 Apr 22;5:180. doi: 10.3389/fimmu.2014.00180. eCollection 2014. Review.


The in vitro addition of methotrexate and/or methylprednisolone determines peripheral reduction in Th17 and expansion of conventional Treg and of IL-10 producing Th17 lymphocytes in patients with early rheumatoid arthritis.

Guggino G, Giardina A, Ferrante A, Giardina G, Schinocca C, Sireci G, Dieli F, Ciccia F, Triolo G.

Rheumatol Int. 2015 Jan;35(1):171-5. doi: 10.1007/s00296-014-3030-2. Epub 2014 May 3.


Efficacy and safety of γδT cell-based tumor immunotherapy: a meta-analysis.

Buccheri S, Guggino G, Caccamo N, Li Donni P, Dieli F.

J Biol Regul Homeost Agents. 2014 Jan-Mar;28(1):81-90.


CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis.

Todaro M, Gaggianesi M, Catalano V, Benfante A, Iovino F, Biffoni M, Apuzzo T, Sperduti I, Volpe S, Cocorullo G, Gulotta G, Dieli F, De Maria R, Stassi G.

Cell Stem Cell. 2014 Mar 6;14(3):342-56. doi: 10.1016/j.stem.2014.01.009.


Detection of natural killer T cells in mice infected with Rickettsia conorii.

La Manna MP, Torina A, Agnone A, Blanda V, Caracappa S, Alongi A, Di Marco V, Giudice E, Dieli F, Sireci G.

Transbound Emerg Dis. 2013 Nov;60 Suppl 2:80-5. doi: 10.1111/tbed.12143.


Targeting IL-6 signalling in early rheumatoid arthritis is followed by Th1 and Th17 suppression and Th2 expansion.

Guggino G, Giardina AR, Raimondo S, Giardina G, Sireci G, Dieli F, Peralta M, Alessandro R, Triolo G, Ciccia F.

Clin Exp Rheumatol. 2014 Jan-Feb;32(1):77-81. Epub 2014 Jan 14.

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