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Results: 1 to 20 of 186

1.

Synthesis, Stereochemical Analysis, and Derivatization of Myricanol Provide New Probes that Promote Autophagic Tau Clearance.

Martin MD, Calcul L, Smith C, Jinwal UK, Fontaine SN, Darling A, Seeley K, Wojtas L, Narayan M, Gestwicki JE, Smith GR, Reitz AB, Baker BJ, Dickey CA.

ACS Chem Biol. 2015 Jan 14. [Epub ahead of print]

PMID:
25588114
[PubMed - as supplied by publisher]
2.

Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency.

Sabbagh JJ, O'Leary JC 3rd, Blair LJ, Klengel T, Nordhues BA, Fontaine SN, Binder EB, Dickey CA.

PLoS One. 2014 Sep 5;9(9):e107241. doi: 10.1371/journal.pone.0107241. eCollection 2014.

PMID:
25191701
[PubMed - in process]
Free PMC Article
3.

Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis.

Selenica ML, Davtyan H, Housley SB, Blair LJ, Gillies A, Nordhues BA, Zhang B, Liu J, Gestwicki JE, Lee DC, Gordon MN, Morgan D, Dickey CA.

J Neuroinflammation. 2014 Sep 3;11:152. doi: 10.1186/s12974-014-0152-0.

PMID:
25183004
[PubMed - in process]
Free PMC Article
4.

Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease.

Blair LJ, Sabbagh JJ, Dickey CA.

Expert Opin Ther Targets. 2014 Oct;18(10):1219-32. doi: 10.1517/14728222.2014.943185. Epub 2014 Jul 29.

PMID:
25069659
[PubMed - in process]
5.

Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma.

Stothert AR, Suntharalingam A, Huard DJ, Fontaine SN, Crowley VM, Mishra S, Blagg BS, Lieberman RL, Dickey CA.

Hum Mol Genet. 2014 Dec 15;23(24):6470-80. doi: 10.1093/hmg/ddu367. Epub 2014 Jul 15.

PMID:
25027323
[PubMed - in process]
6.

Decreasing bullying behaviors in middle school: expect respect.

Nese RN, Horner RH, Dickey CR, Stiller B, Tomlanovich A.

Sch Psychol Q. 2014 Sep;29(3):272-86. doi: 10.1037/spq0000070. Epub 2014 May 12.

PMID:
24820010
[PubMed - in process]
7.

Creating Opportunities for Organizational Leadership (COOL): Creating a culture and curriculum that fosters psychiatric leadership development and quality improvement.

Dickey C, Dismukes R, Topor D.

Acad Psychiatry. 2014 Jun;38(3):383-7. doi: 10.1007/s40596-014-0082-2. Epub 2014 Mar 25.

PMID:
24664604
[PubMed - in process]
8.

Neuropsychiatry and neuroscience education of psychiatry trainees: attitudes and barriers.

Benjamin S, Travis MJ, Cooper JJ, Dickey CC, Reardon CL.

Acad Psychiatry. 2014 Apr;38(2):135-40. doi: 10.1007/s40596-014-0051-9. Epub 2014 Mar 19.

PMID:
24643397
[PubMed - indexed for MEDLINE]
9.

Hsp90-Tau complex reveals molecular basis for specificity in chaperone action.

Karagöz GE, Duarte AM, Akoury E, Ippel H, Biernat J, Morán Luengo T, Radli M, Didenko T, Nordhues BA, Veprintsev DB, Dickey CA, Mandelkow E, Zweckstetter M, Boelens R, Madl T, Rüdiger SG.

Cell. 2014 Feb 27;156(5):963-74. doi: 10.1016/j.cell.2014.01.037.

PMID:
24581495
[PubMed - indexed for MEDLINE]
10.

Decreasing inter-resident conflict by using computer-generated on-call schedules.

Dickey CC, Tarnavsky T, Khan I, Panych LP.

Acad Psychiatry. 2014 Apr;38(2):213-6. doi: 10.1007/s40596-014-0060-8. Epub 2014 Feb 12.

PMID:
24519802
[PubMed - indexed for MEDLINE]
11.

Ligands for glaucoma-associated myocilin discovered by a generic binding assay.

Orwig SD, Chi PV, Du Y, Hill SE, Cavitt MA, Suntharalingam A, Turnage KC, Dickey CA, France S, Fu H, Lieberman RL.

ACS Chem Biol. 2014 Feb 21;9(2):517-25. doi: 10.1021/cb4007776. Epub 2013 Dec 9.

PMID:
24279319
[PubMed - indexed for MEDLINE]
12.

Resident/faculty collaboration for systems-based quality improvement.

Benzer JK, Bauer MS, Charns MP, Topor DR, Dickey CC.

Acad Psychiatry. 2013 Nov;37(6):433-5. doi: 10.1176/appi.ap.12090169. No abstract available.

PMID:
24185294
[PubMed - indexed for MEDLINE]
13.

Working memory in schizotypal personality disorder: fMRI activation and deactivation differences.

Vu MA, Thermenos HW, Terry DP, Wolfe DJ, Voglmaier MM, Niznikiewicz MA, McCarley RW, Seidman LJ, Dickey CC.

Schizophr Res. 2013 Dec;151(1-3):113-23. doi: 10.1016/j.schres.2013.09.013. Epub 2013 Oct 23.

PMID:
24161536
[PubMed - indexed for MEDLINE]
14.

Potential synergy between tau aggregation inhibitors and tau chaperone modulators.

Blair LJ, Zhang B, Dickey CA.

Alzheimers Res Ther. 2013 Sep 16;5(5):41. doi: 10.1186/alzrt207. eCollection 2013. Review.

PMID:
24041111
[PubMed]
Free PMC Article
15.

The role of FKBP5 in mood disorders: action of FKBP5 on steroid hormone receptors leads to questions about its evolutionary importance.

O'Leary JC 3rd, Zhang B, Koren J 3rd, Blair L, Dickey CA.

CNS Neurol Disord Drug Targets. 2013 Dec;12(8):1157-62. Review.

PMID:
24040820
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.

Blair LJ, Nordhues BA, Hill SE, Scaglione KM, O'Leary JC 3rd, Fontaine SN, Breydo L, Zhang B, Li P, Wang L, Cotman C, Paulson HL, Muschol M, Uversky VN, Klengel T, Binder EB, Kayed R, Golde TE, Berchtold N, Dickey CA.

J Clin Invest. 2013 Oct 1;123(10):4158-69. doi: 10.1172/JCI69003. Epub 2013 Sep 3.

PMID:
23999428
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complex.

Smith MC, Scaglione KM, Assimon VA, Patury S, Thompson AD, Dickey CA, Southworth DR, Paulson HL, Gestwicki JE, Zuiderweg ER.

Biochemistry. 2013 Aug 13;52(32):5354-64. doi: 10.1021/bi4009209. Epub 2013 Aug 2.

PMID:
23865999
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Reconstructing the Hsp90/Tau Machine.

Jinwal UK, Koren J 3rd, Dickey CA.

Curr Enzym Inhib. 2013 Jan 1;9(1):41-45.

PMID:
23798910
[PubMed]
Free PMC Article
19.

Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation.

Abisambra JF, Jinwal UK, Blair LJ, O'Leary JC 3rd, Li Q, Brady S, Wang L, Guidi CE, Zhang B, Nordhues BA, Cockman M, Suntharalingham A, Li P, Jin Y, Atkins CA, Dickey CA.

J Neurosci. 2013 May 29;33(22):9498-507. doi: 10.1523/JNEUROSCI.5397-12.2013.

PMID:
23719816
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau.

Abisambra J, Jinwal UK, Miyata Y, Rogers J, Blair L, Li X, Seguin SP, Wang L, Jin Y, Bacon J, Brady S, Cockman M, Guidi C, Zhang J, Koren J, Young ZT, Atkins CA, Zhang B, Lawson LY, Weeber EJ, Brodsky JL, Gestwicki JE, Dickey CA.

Biol Psychiatry. 2013 Sep 1;74(5):367-74. doi: 10.1016/j.biopsych.2013.02.027. Epub 2013 Apr 19.

PMID:
23607970
[PubMed - indexed for MEDLINE]
Free PMC Article

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