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Results: 11

1.

Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families.

Bopp SE, Manary MJ, Bright AT, Johnston GL, Dharia NV, Luna FL, McCormack S, Plouffe D, McNamara CW, Walker JR, Fidock DA, Denchi EL, Winzeler EA.

PLoS Genet. 2013;9(2):e1003293. doi: 10.1371/journal.pgen.1003293. Epub 2013 Feb 7.

PMID:
23408914
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.

Meister S, Plouffe DM, Kuhen KL, Bonamy GM, Wu T, Barnes SW, Bopp SE, Borboa R, Bright AT, Che J, Cohen S, Dharia NV, Gagaring K, Gettayacamin M, Gordon P, Groessl T, Kato N, Lee MC, McNamara CW, Fidock DA, Nagle A, Nam TG, Richmond W, Roland J, Rottmann M, Zhou B, Froissard P, Glynne RJ, Mazier D, Sattabongkot J, Schultz PG, Tuntland T, Walker JR, Zhou Y, Chatterjee A, Diagana TT, Winzeler EA.

Science. 2011 Dec 9;334(6061):1372-7. doi: 10.1126/science.1211936. Epub 2011 Nov 17.

PMID:
22096101
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor.

Nam TG, McNamara CW, Bopp S, Dharia NV, Meister S, Bonamy GM, Plouffe DM, Kato N, McCormack S, Bursulaya B, Ke H, Vaidya AB, Schultz PG, Winzeler EA.

ACS Chem Biol. 2011 Nov 18;6(11):1214-22. doi: 10.1021/cb200105d. Epub 2011 Sep 8.

PMID:
21866942
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites.

Eastman RT, Dharia NV, Winzeler EA, Fidock DA.

Antimicrob Agents Chemother. 2011 Aug;55(8):3908-16. doi: 10.1128/AAC.01793-10. Epub 2011 May 16.

PMID:
21576453
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Validation of isoleucine utilization targets in Plasmodium falciparum.

Istvan ES, Dharia NV, Bopp SE, Gluzman I, Winzeler EA, Goldberg DE.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1627-32. doi: 10.1073/pnas.1011560108. Epub 2011 Jan 4.

PMID:
21205898
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes.

Dharia NV, Bright AT, Westenberger SJ, Barnes SW, Batalov S, Kuhen K, Borboa R, Federe GC, McClean CM, Vinetz JM, Neyra V, Llanos-Cuentas A, Barnwell JW, Walker JR, Winzeler EA.

Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20045-50. doi: 10.1073/pnas.1003776107. Epub 2010 Oct 29.

PMID:
21037109
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites.

Dharia NV, Plouffe D, Bopp SE, González-Páez GE, Lucas C, Salas C, Soberon V, Bursulaya B, Kochel TJ, Bacon DJ, Winzeler EA.

Genome Res. 2010 Nov;20(11):1534-44. doi: 10.1101/gr.105163.110. Epub 2010 Sep 9.

PMID:
20829224
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Spiroindolones, a potent compound class for the treatment of malaria.

Rottmann M, McNamara C, Yeung BK, Lee MC, Zou B, Russell B, Seitz P, Plouffe DM, Dharia NV, Tan J, Cohen SB, Spencer KR, González-Páez GE, Lakshminarayana SB, Goh A, Suwanarusk R, Jegla T, Schmitt EK, Beck HP, Brun R, Nosten F, Renia L, Dartois V, Keller TH, Fidock DA, Winzeler EA, Diagana TT.

Science. 2010 Sep 3;329(5996):1175-80. doi: 10.1126/science.1193225.

PMID:
20813948
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A systems-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito.

Westenberger SJ, McClean CM, Chattopadhyay R, Dharia NV, Carlton JM, Barnwell JW, Collins WE, Hoffman SL, Zhou Y, Vinetz JM, Winzeler EA.

PLoS Negl Trop Dis. 2010 Apr 6;4(4):e653. doi: 10.1371/journal.pntd.0000653.

PMID:
20386602
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Genomics and systems biology in malaria drug discovery.

Dharia NV, Chatterjee A, Winzeler EA.

Curr Opin Investig Drugs. 2010 Feb;11(2):131-8. Review.

PMID:
20112162
[PubMed - indexed for MEDLINE]
11.

Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum.

Dharia NV, Sidhu AB, Cassera MB, Westenberger SJ, Bopp SE, Eastman RT, Plouffe D, Batalov S, Park DJ, Volkman SK, Wirth DF, Zhou Y, Fidock DA, Winzeler EA.

Genome Biol. 2009 Feb 13;10(2):R21. doi: 10.1186/gb-2009-10-2-r21.

PMID:
19216790
[PubMed - indexed for MEDLINE]
Free PMC Article

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