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Detection of antidrug IgG antibodies in patients with adverse drug reactions to amodiaquine.
Clarke JB, Neftel K, Kitteringham NR, Park BK. Clarke JB, et al. Int Arch Allergy Appl Immunol. 1991;95(4):369-75. doi: 10.1159/000235475. Int Arch Allergy Appl Immunol. 1991. PMID: 1959977
Antidrug IgG antibodies have been detected in some patients receiving amodiaquine (AQ). Antidrug antibodies were detected in 6/7 patients who experienced serious well-defined adverse drug react
Antidrug IgG antibodies have been detected in some patients receiving amodiaquine (AQ). Antidru
Drug-protein conjugates--XVIII. Detection of antibodies towards the antimalarial amodiaquine and its quinone imine metabolite in man and the rat.
Christie G, Breckenridge AM, Park BK. Christie G, et al. Biochem Pharmacol. 1989 May 1;38(9):1451-8. doi: 10.1016/0006-2952(89)90184-6. Biochem Pharmacol. 1989. PMID: 2470378
There was no increase in IgG anti-AQ antibody activities in patients who had not exhibited an adverse reaction whilst receiving the drug for the treatment of malaria (-0.059 +/- 0.074 on day 0 and -0.053 +/- 0.068 on day 7, N = 13). Thus, we hav …
There was no increase in IgG anti-AQ antibody activities in patients who had not exhibited an adverse reaction w …