Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 133

1.

Genotoxic mode of action predictions from a multiplexed flow cytometric assay and a machine learning approach.

Bryce SM, Bernacki DT, Bemis JC, Dertinger SD.

Environ Mol Mutagen. 2016 Jan 13. doi: 10.1002/em.21996. [Epub ahead of print]

PMID:
26764165
2.

A proposal for a novel rationale for critical effect size in dose-response analysis based on a multi-endpoint in vivo study with methyl methanesulfonate.

Zeller A, Tang L, Dertinger SD, Funk J, Duran-Pacheco G, Guérard M.

Mutagenesis. 2015 Nov 20. pii: gev077. [Epub ahead of print]

PMID:
26590612
3.

Mouse Pig-a and micronucleus assays respond to N-ethyl-N-nitrosourea, benzo[a]pyrene, and ethyl carbamate, but not pyrene or methyl carbamate.

Labash C, Avlasevich SL, Carlson K, Berg A, Torous DK, Bryce SM, Bemis JC, MacGregor JT, Dertinger SD.

Environ Mol Mutagen. 2016 Jan;57(1):28-40. doi: 10.1002/em.21965. Epub 2015 Jul 17.

PMID:
26186091
4.

Comparison of in vitro and in vivo clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data.

Bemis JC, Wills JW, Bryce SM, Torous DK, Dertinger SD, Slob W.

Mutagenesis. 2015 Jun 6. pii: gev041. [Epub ahead of print]

PMID:
26049158
5.

The in vivo Pig-a assay: A report of the International Workshop On Genotoxicity Testing (IWGT) Workgroup.

Gollapudi BB, Lynch AM, Heflich RH, Dertinger SD, Dobrovolsky VN, Froetschl R, Horibata K, Kenyon MO, Kimoto T, Lovell DP, Stankowski LF Jr, White PA, Witt KL, Tanir JY.

Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:23-35. doi: 10.1016/j.mrgentox.2014.09.007. Epub 2014 Sep 26.

PMID:
25953398
6.

Continued progress in developing the Pig-a gene mutation assay.

Heflich RH, Dobrovolsky VN, Dertinger SD.

Mutagenesis. 2015 May;30(3):313-4. doi: 10.1093/mutage/geu082. Epub 2015 May 1.

PMID:
25934984
7.

Induction of Pig-a mutant erythrocytes in male and female rats exposed to 1,3-propane sultone, ethyl carbamate, or thiotepa.

Labash C, Carlson K, Avlasevich SL, Berg A, Bemis JC, MacGregor JT, Dertinger SD.

Mutat Res Genet Toxicol Environ Mutagen. 2015 Apr;782:24-9. doi: 10.1016/j.mrgentox.2015.03.011. Epub 2015 Mar 14.

PMID:
25868128
8.

Part 2. Assessment of micronucleus formation in rats after chronic exposure to new-technology diesel exhaust in the ACES bioassay.

Bemis JC, Torous DK, Dertinger SD; HEI Health Review Committee.

Res Rep Health Eff Inst. 2015 Jan;(184):69-82; discussion 141-71.

PMID:
25842616
9.

Rat Pig-a mutation assay responds to the genotoxic carcinogen ethyl carbamate but not the non-genotoxic carcinogen methyl carbamate.

Bemis JC, Labash C, Avlasevich SL, Carlson K, Berg A, Torous DK, Barragato M, MacGregor JT, Dertinger SD.

Mutagenesis. 2015 May;30(3):343-7. doi: 10.1093/mutage/geu084. Epub 2015 Apr 1.

PMID:
25833916
10.

Comparison of male versus female responses in the Pig-a mutation assay.

Labash C, Avlasevich SL, Carlson K, Torous DK, Berg A, Bemis JC, MacGregor JT, Dertinger SD.

Mutagenesis. 2015 May;30(3):349-57. doi: 10.1093/mutage/geu055. Epub 2015 Apr 1.

PMID:
25833915
11.

Compensatory erythropoiesis has no impact on the outcome of the in vivo Pig-a mutation assay in rats following treatment with the haemolytic agent 2-butoxyethanol.

Kenyon MO, Coffing SL, Ackerman JI, Gunther WC, Dertinger SD, Criswell K, Dobo KL.

Mutagenesis. 2015 May;30(3):325-34. doi: 10.1093/mutage/geu051. Epub 2015 Mar 27.

PMID:
25820171
12.

Human erythrocyte PIG-A assay: an easily monitored index of gene mutation requiring low volume blood samples.

Dertinger SD, Avlasevich SL, Bemis JC, Chen Y, MacGregor JT.

Environ Mol Mutagen. 2015 May;56(4):366-77. doi: 10.1002/em.21924. Epub 2014 Nov 20.

PMID:
25412990
13.

Genotoxic effects of two-generational selenium deficiency in mouse somatic and testicular cells.

Graupner A, Instanes C, Andersen JM, Brandt-Kjelsen A, Dertinger SD, Salbu B, Brunborg G, Olsen AK.

Mutagenesis. 2015 Mar;30(2):217-25. doi: 10.1093/mutage/geu059. Epub 2014 Oct 30.

PMID:
25358475
14.

Single cell gel electrophoresis (SCGE) and Pig-a mutation assay in vivo-tools for genotoxicity testing from a regulatory perspective: a study of benzo[a]pyrene in Ogg1(-/-) mice.

Graupner A, Instanes C, Dertinger SD, Andersen JM, Lindeman B, Rongved TD, Brunborg G, Olsen AK.

Mutat Res Genet Toxicol Environ Mutagen. 2014 Sep 15;772:34-41. doi: 10.1016/j.mrgentox.2014.07.010. Epub 2014 Aug 7.

15.

Inter-laboratory validation of the in-vivo flow cytometric micronucleus analysis method (MicroFlow®) in China.

Chang Y, Zhou C, Huang F, Torous DK, Luan Y, Shi C, Wang H, Wang X, Wei N, Xia Z, Zhong Z, Zhang M, An F, Cao Y, Geng X, Jiang Y, Ju Q, Yu Y, Zhu J, Dertinger SD, Li B, Liao M, Yuan B, Zhang T, Yu J, Zhang Z, Wang Q, Ma J.

Mutat Res Genet Toxicol Environ Mutagen. 2014 Sep 15;772:6-13. doi: 10.1016/j.mrgentox.2014.04.027. Epub 2014 Jul 23.

PMID:
25308541
16.

Assessment of 5-fluorouracil and 4-nitroquinoline-1-oxide in vivo genotoxicity with Pig-a mutation and micronucleus endpoints.

Zhou C, Zhang M, Huang P, Tu H, Wang Z, Dertinger SD, Torous DK, Chang Y.

Environ Mol Mutagen. 2014 Dec;55(9):735-40. doi: 10.1002/em.21893. Epub 2014 Aug 14.

PMID:
25124805
17.

Persistence of cisplatin-induced mutagenicity in hematopoietic stem cells: implications for secondary cancer risk following chemotherapy.

Dertinger SD, Avlasevich SL, Torous DK, Bemis JC, Phonethepswath S, Labash C, Carlson K, Mereness J, Cottom J, Palis J, MacGregor JT.

Toxicol Sci. 2014 Aug 1;140(2):307-14. doi: 10.1093/toxsci/kfu078. Epub 2014 May 5.

18.

Predictors of splenic function preservation in children with sickle cell anemia treated with hydroxyurea.

Nottage KA, Ware RE, Winter B, Smeltzer M, Wang WC, Hankins JS, Dertinger SD, Shulkin B, Aygun B.

Eur J Haematol. 2014 Nov;93(5):377-83. doi: 10.1111/ejh.12361. Epub 2014 Jun 2.

PMID:
24796940
19.

Interpreting in vitro micronucleus positive results: simple biomarker matrix discriminates clastogens, aneugens, and misleading positive agents.

Bryce SM, Bemis JC, Mereness JA, Spellman RA, Moss J, Dickinson D, Schuler MJ, Dertinger SD.

Environ Mol Mutagen. 2014 Aug;55(7):542-55. doi: 10.1002/em.21868. Epub 2014 Apr 23.

PMID:
24756928
20.

Diethylnitrosamine genotoxicity evaluated in sprague dawley rats using pig-a mutation and reticulocyte micronucleus assays.

Avlasevich SL, Phonethepswath S, Labash C, Carlson K, Torous DK, Cottom J, Bemis JC, MacGregor JT, Dertinger SD.

Environ Mol Mutagen. 2014 Jun;55(5):400-6. doi: 10.1002/em.21862. Epub 2014 Feb 27.

PMID:
24574022
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk