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Items: 17


A chemical genetics approach for the functional assessment of novel cancer genes.

Zhou Q, Derti A, Ruddy D, Rakiec D, Kao I, Lira M, Gibaja V, Chan H, Yang Y, Min J, Schlabach MR, Stegmeier F.

Cancer Res. 2015 May 15;75(10):1949-58. doi: 10.1158/0008-5472.CAN-14-2930. Epub 2015 Mar 18.


Loss of Tuberous Sclerosis Complex 2 (TSC2) Is Frequent in Hepatocellular Carcinoma and Predicts Response to mTORC1 Inhibitor Everolimus.

Huynh H, Hao HX, Chan SL, Chen D, Ong R, Soo KC, Pochanard P, Yang D, Ruddy D, Liu M, Derti A, Balak MN, Palmer MR, Wang Y, Lee BH, Sellami D, Zhu AX, Schlegel R, Huang A.

Mol Cancer Ther. 2015 May;14(5):1224-35. doi: 10.1158/1535-7163.MCT-14-0768. Epub 2015 Feb 27.


Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor.

Juric D, Castel P, Griffith M, Griffith OL, Won HH, Ellis H, Ebbesen SH, Ainscough BJ, Ramu A, Iyer G, Shah RH, Huynh T, Mino-Kenudson M, Sgroi D, Isakoff S, Thabet A, Elamine L, Solit DB, Lowe SW, Quadt C, Peters M, Derti A, Schegel R, Huang A, Mardis ER, Berger MF, Baselga J, Scaltriti M.

Nature. 2015 Feb 12;518(7538):240-4. doi: 10.1038/nature13948. Epub 2014 Nov 17.


Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma.

Rahal R, Frick M, Romero R, Korn JM, Kridel R, Chan FC, Meissner B, Bhang HE, Ruddy D, Kauffmann A, Farsidjani A, Derti A, Rakiec D, Naylor T, Pfister E, Kovats S, Kim S, Dietze K, Dörken B, Steidl C, Tzankov A, Hummel M, Monahan J, Morrissey MP, Fritsch C, Sellers WR, Cooke VG, Gascoyne RD, Lenz G, Stegmeier F.

Nat Med. 2014 Jan;20(1):87-92. doi: 10.1038/nm.3435. Epub 2013 Dec 22.


A quantitative atlas of polyadenylation in five mammals.

Derti A, Garrett-Engele P, Macisaac KD, Stevens RC, Sriram S, Chen R, Rohl CA, Johnson JM, Babak T.

Genome Res. 2012 Jun;22(6):1173-83. doi: 10.1101/gr.132563.111. Epub 2012 Mar 27.


Genome analysis reveals interplay between 5'UTR introns and nuclear mRNA export for secretory and mitochondrial genes.

Cenik C, Chua HN, Zhang H, Tarnawsky SP, Akef A, Derti A, Tasan M, Moore MJ, Palazzo AF, Roth FP.

PLoS Genet. 2011 Apr;7(4):e1001366. doi: 10.1371/journal.pgen.1001366. Epub 2011 Apr 14.


Absence of evidence for MHC-dependent mate selection within HapMap populations.

Derti A, Cenik C, Kraft P, Roth FP.

PLoS Genet. 2010 Apr 29;6(4):e1000925. doi: 10.1371/journal.pgen.1000925.


Genome-wide functional analysis of human 5' untranslated region introns.

Cenik C, Derti A, Mellor JC, Berriz GF, Roth FP.

Genome Biol. 2010;11(3):R29. doi: 10.1186/gb-2010-11-3-r29. Epub 2010 Mar 11.


Ultraconserved elements: analyses of dosage sensitivity, motifs and boundaries.

Chiang CW, Derti A, Schwartz D, Chou MF, Hirschhorn JN, Wu CT.

Genetics. 2008 Dec;180(4):2277-93. doi: 10.1534/genetics.108.096537. Epub 2008 Oct 28.


Isoform discovery by targeted cloning, 'deep-well' pooling and parallel sequencing.

Salehi-Ashtiani K, Yang X, Derti A, Tian W, Hao T, Lin C, Makowski K, Shen L, Murray RR, Szeto D, Tusneem N, Smith DR, Cusick ME, Hill DE, Roth FP, Vidal M.

Nat Methods. 2008 Jul;5(7):597-600. doi: 10.1038/nmeth.1224. Epub 2008 Jun 15.


Mammalian ultraconserved elements are strongly depleted among segmental duplications and copy number variants.

Derti A, Roth FP, Church GM, Wu CT.

Nat Genet. 2006 Oct;38(10):1216-20. Epub 2006 Sep 24.


Gene expression in lung adenocarcinomas of smokers and nonsmokers.

Powell CA, Spira A, Derti A, DeLisi C, Liu G, Borczuk A, Busch S, Sahasrabudhe S, Chen Y, Sugarbaker D, Bueno R, Richards WG, Brody JS.

Am J Respir Cell Mol Biol. 2003 Aug;29(2):157-62. Epub 2003 Feb 21.


A computational framework for optimal masking in the synthesis of oligonucleotide microarrays.

Kasif S, Weng Z, Derti A, Beigel R, DeLisi C.

Nucleic Acids Res. 2002 Oct 15;30(20):e106.


Computational comparison of two draft sequences of the human genome.

Aach J, Bulyk ML, Church GM, Comander J, Derti A, Shendure J.

Nature. 2001 Feb 15;409(6822):856-9.


ProbeDesigner: for the design of probesets for branched DNA (bDNA) signal amplification assays.

Bushnell S, Budde J, Catino T, Cole J, Derti A, Kelso R, Collins ML, Molino G, Sheridan P, Monahan J, Urdea M.

Bioinformatics. 1999 May;15(5):348-55.

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