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Grainyhead-like-2 inhibits the coactivator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition.

Pifer PM, Farris JC, Thomas AL, Stoilov P, Denvir J, Smith DM, Frisch SM.

Mol Biol Cell. 2016 Jun 1. pii: mbc.E16-04-0249. [Epub ahead of print]


Grainyhead-like 2 Reverses the Metabolic Changes Induced by the Oncogenic Epithelial-Mesenchymal Transition: Effects on Anoikis.

Farris JC, Pifer PM, Zheng L, Gottlieb E, Denvir J, Frisch SM.

Mol Cancer Res. 2016 Jun;14(6):528-38. doi: 10.1158/1541-7786.MCR-16-0050. Epub 2016 Apr 15.


Aryl hydrocarbon receptor (AHR) regulation of L-Type Amino Acid Transporter 1 (LAT-1) expression in MCF-7 and MDA-MB-231 breast cancer cells.

Tomblin JK, Arthur S, Primerano DA, Chaudhry AR, Fan J, Denvir J, Salisbury TB.

Biochem Pharmacol. 2016 Apr 15;106:94-103. doi: 10.1016/j.bcp.2016.02.020. Epub 2016 Mar 2.


Identification of the PS1 Thr147Ile Variant in a Family with Very Early Onset Dementia and Expressive Aphasia.

Denvir J, Neitch S, Fan J, Niles RM, Boskovic G, Schreurs BG, Primerano DA, Alkon DL.

J Alzheimers Dis. 2015;46(2):483-90. doi: 10.3233/JAD-150051.


RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells.

Carper MB, Denvir J, Boskovic G, Primerano DA, Claudio PP.

Genes Cancer. 2014 Nov;5(11-12):420-35.


Severe hypoglycemia and coronary artery calcification during the diabetes control and complications trial/epidemiology of diabetes interventions and complications (DCCT/EDIC) study.

Fährmann ER, Adkins L, Loader CJ, Han H, Rice KM, Denvir J, Driscoll HK.

Diabetes Res Clin Pract. 2015 Feb;107(2):280-9. doi: 10.1016/j.diabres.2014.10.007. Epub 2014 Oct 23.


Chemo-predictive assay for targeting cancer stem-like cells in patients affected by brain tumors.

Mathis SE, Alberico A, Nande R, Neto W, Lawrence L, McCallister DR, Denvir J, Kimmey GA, Mogul M, Oakley G 3rd, Denning KL, Dougherty T, Valluri JV, Claudio PP.

PLoS One. 2014 Aug 21;9(8):e105710. doi: 10.1371/journal.pone.0105710. eCollection 2014.


A genomic profile of the immune response to stroke with implications for stroke recovery.

Barr TL, VanGilder R, Rellick S, Brooks SD, Doll DN, Lucke-Wold AN, Chen D, Denvir J, Warach S, Singleton A, Matarin M.

Biol Res Nurs. 2015 May;17(3):248-56. doi: 10.1177/1099800414546492. Epub 2014 Aug 14.


Endogenous aryl hydrocarbon receptor promotes basal and inducible expression of tumor necrosis factor target genes in MCF-7 cancer cells.

Salisbury TB, Tomblin JK, Primerano DA, Boskovic G, Fan J, Mehmi I, Fletcher J, Santanam N, Hurn E, Morris GZ, Denvir J.

Biochem Pharmacol. 2014 Oct 1;91(3):390-9. doi: 10.1016/j.bcp.2014.06.015. Epub 2014 Jun 24.


Epithelial-mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2.

Cieply B, Farris J, Denvir J, Ford HL, Frisch SM.

Cancer Res. 2013 Oct 15;73(20):6299-309. doi: 10.1158/0008-5472.CAN-12-4082. Epub 2013 Aug 13.


System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses.

Snyder-Talkington BN, Dymacek J, Porter DW, Wolfarth MG, Mercer RR, Pacurari M, Denvir J, Castranova V, Qian Y, Guo NL.

Toxicol Appl Pharmacol. 2013 Oct 15;272(2):476-89. doi: 10.1016/j.taap.2013.06.026. Epub 2013 Jul 8.


Microbubble-assisted p53, RB, and p130 gene transfer in combination with radiation therapy in prostate cancer.

Nande R, Greco A, Gossman MS, Lopez JP, Claudio L, Salvatore M, Brunetti A, Denvir J, Howard CM, Claudio PP.

Curr Gene Ther. 2013 Jun 1;13(3):163-74.


Inhibition of nuclear factor kappa B activation in early-stage chronic lymphocytic leukemia by omega-3 fatty acids.

Fahrmann JF, Ballester OF, Ballester G, Witte TR, Salazar AJ, Kordusky B, Cowen KG, Ion G, Primerano DA, Boskovic G, Denvir J, Hardman WE.

Cancer Invest. 2013 Jan;31(1):24-38. doi: 10.3109/07357907.2012.743553. Epub 2012 Nov 29.


High throughput DNA sequencing to detect differences in the subgingival plaque microbiome in elderly subjects with and without dementia.

Cockburn AF, Dehlin JM, Ngan T, Crout R, Boskovic G, Denvir J, Primerano D, Plassman BL, Wu B, Cuff CF.

Investig Genet. 2012 Sep 21;3(1):19. doi: 10.1186/2041-2223-3-19.


Multiwalled carbon nanotube-induced gene signatures in the mouse lung: potential predictive value for human lung cancer risk and prognosis.

Guo NL, Wan YW, Denvir J, Porter DW, Pacurari M, Wolfarth MG, Castranova V, Qian Y.

J Toxicol Environ Health A. 2012;75(18):1129-53. doi: 10.1080/15287394.2012.699852.


Targeting a newly established spontaneous feline fibrosarcoma cell line by gene transfer.

Nande R, Di Benedetto A, Aimola P, De Carlo F, Carper M, Claudio CD, Denvir J, Valluri J, Duncan GC, Claudio PP.

PLoS One. 2012;7(5):e37743. doi: 10.1371/journal.pone.0037743. Epub 2012 May 30.


Suppression of the epithelial-mesenchymal transition by Grainyhead-like-2.

Cieply B, Riley P 4th, Pifer PM, Widmeyer J, Addison JB, Ivanov AV, Denvir J, Frisch SM.

Cancer Res. 2012 May 1;72(9):2440-53. doi: 10.1158/0008-5472.CAN-11-4038. Epub 2012 Feb 29.


Bone marrow osteoblast damage by chemotherapeutic agents.

Rellick SL, O'Leary H, Piktel D, Walton C, Fortney JE, Akers SM, Martin KH, Denvir J, Boskovic G, Primerano DA, Vos J, Bailey N, Gencheva M, Gibson LF.

PLoS One. 2012;7(2):e30758. doi: 10.1371/journal.pone.0030758. Epub 2012 Feb 17.


Melphalan exposure induces an interleukin-6 deficit in bone marrow stromal cells and osteoblasts.

Rellick SL, Piktel D, Walton C, Hall B, Petros W, Fortney JE, Gencheva M, Denvir J, Hobbs G, Craig M, Gibson LF.

Cytokine. 2012 May;58(2):245-52. doi: 10.1016/j.cyto.2012.01.012. Epub 2012 Feb 21.


Identification of genes contributing to cardiovascular disease in overweight and obese individuals from West Virginia.

Dementieva Y, Green TL, Primerano DA, Wei L, Denvir J, Wehner P, Dodson S, Flood MR, Pollock BA, Huff M, Hill C, Kreisberg R, Francis A, Morrison K, Blackwood H, Davis M, Lee HM, Warren S; Appalachian Cardiovascular Research Network.

W V Med J. 2012 Jan-Feb;108(1):23-6, 28-30.

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