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Results: 15

1.

Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.

Pant M, Sopariwala DH, Bal NC, Lowe J, Delfín DA, Rafael-Fortney J, Periasamy M.

PLoS One. 2015 Apr 10;10(4):e0123875. doi: 10.1371/journal.pone.0123875. eCollection 2015.

2.

Claudin-5 levels are reduced from multiple cell types in human failing hearts and are associated with mislocalization of ephrin-B1.

Swager SA, Delfín DA, Rastogi N, Wang H, Canan BD, Fedorov VV, Mohler PJ, Kilic A, Higgins RS, Ziolo MT, Janssen PM, Rafael-Fortney JA.

Cardiovasc Pathol. 2015 May-Jun;24(3):160-7. doi: 10.1016/j.carpath.2014.10.006. Epub 2014 Nov 7.

PMID:
25440958
3.

Cholesterol regulation of PIP(2): why cell type is so important.

Taglieri DM, Delfín DA, Monasky MM.

Front Physiol. 2013 Jan 7;3:492. doi: 10.3389/fphys.2012.00492. eCollection 2012. No abstract available.

4.

Cardiomyopathy in the dystrophin/utrophin-deficient mouse model of severe muscular dystrophy is characterized by dysregulation of matrix metalloproteinases.

Delfín DA, Zang KE, Schill KE, Patel NT, Janssen PM, Raman SV, Rafael-Fortney JA.

Neuromuscul Disord. 2012 Nov;22(11):1006-14. doi: 10.1016/j.nmd.2012.05.002. Epub 2012 Jun 29.

5.

Sustaining cardiac claudin-5 levels prevents functional hallmarks of cardiomyopathy in a muscular dystrophy mouse model.

Delfín DA, Xu Y, Schill KE, Mays TA, Canan BD, Zang KE, Barnum JA, Janssen PM, Rafael-Fortney JA.

Mol Ther. 2012 Jul;20(7):1378-83. doi: 10.1038/mt.2012.81. Epub 2012 May 1.

6.

Early treatment with lisinopril and spironolactone preserves cardiac and skeletal muscle in Duchenne muscular dystrophy mice.

Rafael-Fortney JA, Chimanji NS, Schill KE, Martin CD, Murray JD, Ganguly R, Stangland JE, Tran T, Xu Y, Canan BD, Mays TA, Delfín DA, Janssen PM, Raman SV.

Circulation. 2011 Aug 2;124(5):582-8. doi: 10.1161/CIRCULATIONAHA.111.031716. Epub 2011 Jul 18.

7.

Improvement of cardiac contractile function by peptide-based inhibition of NF-κB in the utrophin/dystrophin-deficient murine model of muscular dystrophy.

Delfín DA, Xu Y, Peterson JM, Guttridge DC, Rafael-Fortney JA, Janssen PM.

J Transl Med. 2011 May 17;9:68. doi: 10.1186/1479-5876-9-68.

8.

Peptide-based inhibition of NF-κB rescues diaphragm muscle contractile dysfunction in a murine model of Duchenne muscular dystrophy.

Peterson JM, Kline W, Canan BD, Ricca DJ, Kaspar B, Delfín DA, DiRienzo K, Clemens PR, Robbins PD, Baldwin AS, Flood P, Kaumaya P, Freitas M, Kornegay JN, Mendell JR, Rafael-Fortney JA, Guttridge DC, Janssen PM.

Mol Med. 2011 May-Jun;17(5-6):508-15. doi: 10.2119/molmed.2010.00263. Epub 2011 Jan 20.

9.

Lengthening-contractions in isolated myocardium impact force development and worsen cardiac contractile function in the mdx mouse model of muscular dystrophy.

Xu Y, Delfín DA, Rafael-Fortney JA, Janssen PM.

J Appl Physiol (1985). 2011 Feb;110(2):512-9. doi: 10.1152/japplphysiol.00253.2010. Epub 2010 Dec 2.

10.

Antitrypanosomal activity of 1,2-dihydroquinolin-6-ols and their ester derivatives.

Fotie J, Kaiser M, Delfín DA, Manley J, Reid CS, Paris JM, Wenzler T, Maes L, Mahasenan KV, Li C, Werbovetz KA.

J Med Chem. 2010 Feb 11;53(3):966-82. doi: 10.1021/jm900723w.

PMID:
20047276
11.

Impairment of diastolic function by lack of frequency-dependent myofilament desensitization rabbit right ventricular hypertrophy.

Varian KD, Kijtawornrat A, Gupta SC, Torres CA, Monasky MM, Hiranandani N, Delfin DA, Rafael-Fortney JA, Periasamy M, Hamlin RL, Janssen PM.

Circ Heart Fail. 2009 Sep;2(5):472-81. doi: 10.1161/CIRCHEARTFAILURE.109.853200. Epub 2009 Jul 21.

12.

Redox-active dinitrodiphenylthioethers against Leishmania: synthesis, structure-activity relationships and mechanism of action studies.

Delfín DA, Morgan RE, Zhu X, Werbovetz KA.

Bioorg Med Chem. 2009 Jan 15;17(2):820-9. doi: 10.1016/j.bmc.2008.11.031. Epub 2008 Nov 19.

PMID:
19058972
13.

Synthesis, biological evaluation, and molecular modeling of 3,5-substituted-N1-phenyl-N4,N4-di-n-butylsulfanilamides as antikinetoplastid antimicrotubule agents.

George TG, Endeshaw MM, Morgan RE, Mahasenan KV, Delfín DA, Mukherjee MS, Yakovich AJ, Fotie J, Li C, Werbovetz KA.

Bioorg Med Chem. 2007 Sep 15;15(18):6071-9. Epub 2007 Jun 27.

14.
15.

Antikinetoplastid antimitotic activity and metabolic stability of dinitroaniline sulfonamides and benzamides.

George TG, Johnsamuel J, Delfín DA, Yakovich A, Mukherjee M, Phelps MA, Dalton JT, Sackett DL, Kaiser M, Brun R, Werbovetz KA.

Bioorg Med Chem. 2006 Aug 15;14(16):5699-710. Epub 2006 May 3.

PMID:
16675220
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