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Results: 1 to 20 of 116

1.

Factor XIII activity mediates red blood cell retention in venous thrombi.

Aleman MM, Byrnes JR, Wang JG, Tran R, Lam WA, Di Paola J, Mackman N, Degen JL, Flick MJ, Wolberg AS.

J Clin Invest. 2014 Jul 1. pii: 75386. doi: 10.1172/JCI75386. [Epub ahead of print]

PMID:
24983320
[PubMed - as supplied by publisher]
2.

Early detection of thrombin activity in neuroinflammatory disease.

Davalos D, Baeten KM, Whitney MA, Mullins ES, Friedman B, Olson ES, Ryu JK, Smirnoff DS, Petersen MA, Bedard C, Degen JL, Tsien RY, Akassoglou K.

Ann Neurol. 2014 Feb;75(2):303-8. doi: 10.1002/ana.24078. Epub 2014 Feb 24.

PMID:
24740641
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Fibrin accumulation secondary to loss of plasmin-mediated fibrinolysis drives inflammatory osteoporosis in mice.

Cole HA, Ohba T, Nyman JS, Hirotaka H, Cates JM, Flick MJ, Degen JL, Schoenecker JG.

Arthritis Rheumatol. 2014 Aug;66(8):2222-33. doi: 10.1002/art.38639.

PMID:
24664548
[PubMed - in process]
4.

Plasminogen is a joint-specific positive or negative determinant of arthritis pathogenesis in mice.

Raghu H, Jone A, Cruz C, Rewerts CL, Frederick MD, Thornton S, Degen JL, Flick MJ.

Arthritis Rheumatol. 2014 Jun;66(6):1504-16. doi: 10.1002/art.38402.

PMID:
24574269
[PubMed - in process]
5.

Role of fibrinogen in acute ischemic kidney injury.

Sörensen-Zender I, Rong S, Susnik N, Lange J, Gueler F, Degen JL, Melk A, Haller H, Schmitt R.

Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F777-85. doi: 10.1152/ajprenal.00418.2012. Epub 2013 Jun 26.

PMID:
23804451
[PubMed - indexed for MEDLINE]
6.

Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner.

Borissoff JI, Otten JJ, Heeneman S, Leenders P, van Oerle R, Soehnlein O, Loubele ST, Hamulyák K, Hackeng TM, Daemen MJ, Degen JL, Weiler H, Esmon CT, van Ryn J, Biessen EA, Spronk HM, ten Cate H.

PLoS One. 2013;8(2):e55784. doi: 10.1371/journal.pone.0055784. Epub 2013 Feb 7.

PMID:
23409043
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia.

Flick MJ, Du X, Prasad JM, Raghu H, Palumbo JS, Smeds E, Höök M, Degen JL.

Blood. 2013 Mar 7;121(10):1783-94. doi: 10.1182/blood-2012-09-453894. Epub 2013 Jan 8.

PMID:
23299312
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation.

Davalos D, Ryu JK, Merlini M, Baeten KM, Le Moan N, Petersen MA, Deerinck TJ, Smirnoff DS, Bedard C, Hakozaki H, Gonias Murray S, Ling JB, Lassmann H, Degen JL, Ellisman MH, Akassoglou K.

Nat Commun. 2012;3:1227. doi: 10.1038/ncomms2230.

PMID:
23187627
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Hemostatic factors, innate immunity and malignancy.

Degen JL, Palumbo JS.

Thromb Res. 2012 Apr;129 Suppl 1:S1-5. doi: 10.1016/S0049-3848(12)70143-3.

PMID:
22682116
[PubMed - indexed for MEDLINE]
10.

Amelioration of Duchenne muscular dystrophy in mdx mice by elimination of matrix-associated fibrin-driven inflammation coupled to the αMβ2 leukocyte integrin receptor.

Vidal B, Ardite E, Suelves M, Ruiz-Bonilla V, Janué A, Flick MJ, Degen JL, Serrano AL, Muñoz-Cánoves P.

Hum Mol Genet. 2012 May 1;21(9):1989-2004. doi: 10.1093/hmg/dds012. Epub 2012 Mar 1.

PMID:
22381526
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Platelet TGF-β1 contributions to plasma TGF-β1, cardiac fibrosis, and systolic dysfunction in a mouse model of pressure overload.

Meyer A, Wang W, Qu J, Croft L, Degen JL, Coller BS, Ahamed J.

Blood. 2012 Jan 26;119(4):1064-74. doi: 10.1182/blood-2011-09-377648. Epub 2011 Dec 1.

PMID:
22134166
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Thrombomodulin is a determinant of metastasis through a mechanism linked to the thrombin binding domain but not the lectin-like domain.

Horowitz NA, Blevins EA, Miller WM, Perry AR, Talmage KE, Mullins ES, Flick MJ, Queiroz KC, Shi K, Spek CA, Conway EM, Monia BP, Weiler H, Degen JL, Palumbo JS.

Blood. 2011 Sep 8;118(10):2889-95. doi: 10.1182/blood-2011-03-341222. Epub 2011 Jul 25.

PMID:
21788337
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Fibrinogen, acting as a mitogen for tubulointerstitial fibroblasts, promotes renal fibrosis.

Sörensen I, Susnik N, Inhester T, Degen JL, Melk A, Haller H, Schmitt R.

Kidney Int. 2011 Nov;80(10):1035-44. doi: 10.1038/ki.2011.214. Epub 2011 Jul 6.

PMID:
21734641
[PubMed - indexed for MEDLINE]
14.

The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A.

Flick MJ, Chauhan AK, Frederick M, Talmage KE, Kombrinck KW, Miller W, Mullins ES, Palumbo JS, Zheng X, Esmon NL, Esmon CT, Thornton S, Becker A, Pelc LA, Di Cera E, Wagner DD, Degen JL.

Blood. 2011 Jun 9;117(23):6326-37. doi: 10.1182/blood-2010-08-304915. Epub 2011 Mar 24.

PMID:
21436072
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Binding of Efb from Staphylococcus aureus to fibrinogen blocks neutrophil adherence.

Ko YP, Liang X, Smith CW, Degen JL, Höök M.

J Biol Chem. 2011 Mar 18;286(11):9865-74. doi: 10.1074/jbc.M110.199687. Epub 2011 Jan 19.

PMID:
21247890
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo.

Munks MW, McKee AS, Macleod MK, Powell RL, Degen JL, Reisdorph NA, Kappler JW, Marrack P.

Blood. 2010 Dec 9;116(24):5191-9. doi: 10.1182/blood-2010-03-275529. Epub 2010 Sep 27.

PMID:
20876456
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Mechanisms coupling the hemostatic system to colitis-associated cancer.

Palumbo JS, Degen JL.

Thromb Res. 2010 Apr;125 Suppl 2:S39-43. doi: 10.1016/S0049-3848(10)70011-6. Review. No abstract available.

PMID:
20434003
[PubMed - indexed for MEDLINE]
18.

Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-beta after vascular damage.

Schachtrup C, Ryu JK, Helmrick MJ, Vagena E, Galanakis DK, Degen JL, Margolis RU, Akassoglou K.

J Neurosci. 2010 Apr 28;30(17):5843-54. doi: 10.1523/JNEUROSCI.0137-10.2010.

PMID:
20427645
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Activation of single-chain urokinase-type plasminogen activator by platelet-associated plasminogen: a mechanism for stimulation of fibrinolysis by platelets.

Baeten KM, Richard MC, Kanse SM, Mutch NJ, Degen JL, Booth NA.

J Thromb Haemost. 2010 Jun;8(6):1313-22. doi: 10.1111/j.1538-7836.2010.03813.x. Epub 2010 Feb 17.

PMID:
20180903
[PubMed - indexed for MEDLINE]
20.

Fibrinogen is required for maintenance of platelet intracellular and cell-surface P-selectin expression.

Yang H, Lang S, Zhai Z, Li L, Kahr WH, Chen P, Brkić J, Spring CM, Flick MJ, Degen JL, Freedman J, Ni H.

Blood. 2009 Jul 9;114(2):425-36. doi: 10.1182/blood-2008-03-145821. Epub 2009 Mar 30.

PMID:
19332769
[PubMed - indexed for MEDLINE]
Free Article

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