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Results: 16


Blood-based identification of non-responders to anti-TNF therapy in rheumatoid arthritis.

Thomson TM, Lescarbeau RM, Drubin DA, Laifenfeld D, de Graaf D, Fryburg DA, Littman B, Deehan R, Van Hooser A.

BMC Med Genomics. 2015 Jun 3;8:26. doi: 10.1186/s12920-015-0100-6.


A vascular biology network model focused on inflammatory processes to investigate atherogenesis and plaque instability.

De León H, Boué S, Schlage WK, Boukharov N, Westra JW, Gebel S, VanHooser A, Talikka M, Fields RB, Veljkovic E, Peck MJ, Mathis C, Hoang V, Poussin C, Deehan R, Stolle K, Hoeng J, Peitsch MC.

J Transl Med. 2014 Jun 26;12:185. doi: 10.1186/1479-5876-12-185.


A modular cell-type focused inflammatory process network model for non-diseased pulmonary tissue.

Westra JW, Schlage WK, Hengstermann A, Gebel S, Mathis C, Thomson T, Wong B, Hoang V, Veljkovic E, Peck M, Lichtner RB, Weisensee D, Talikka M, Deehan R, Hoeng J, Peitsch MC.

Bioinform Biol Insights. 2013 Jun 20;7:167-92. doi: 10.4137/BBI.S11509. Print 2013.


Construction of a computable network model for DNA damage, autophagy, cell death, and senescence.

Gebel S, Lichtner RB, Frushour B, Schlage WK, Hoang V, Talikka M, Hengstermann A, Mathis C, Veljkovic E, Peck M, Peitsch MC, Deehan R, Hoeng J, Westra JW.

Bioinform Biol Insights. 2013;7:97-117. doi: 10.4137/BBI.S11154. Epub 2013 Mar 7.


Comparative transcriptional network modeling of three PPAR-α/γ co-agonists reveals distinct metabolic gene signatures in primary human hepatocytes.

Deehan R, Maerz-Weiss P, Catlett NL, Steiner G, Wong B, Wright MB, Blander G, Elliston KO, Ladd W, Bobadilla M, Mizrahi J, Haefliger C, Edgar A.

PLoS One. 2012;7(4):e35012. doi: 10.1371/journal.pone.0035012. Epub 2012 Apr 13.


Genes associated with intestinal permeability in ulcerative colitis: changes in expression following infliximab therapy.

Toedter G, Li K, Sague S, Ma K, Marano C, Macoritto M, Park J, Deehan R, Matthews A, Wu GD, Lewis JD, Arijs I, Rutgeerts P, Baribaud F.

Inflamm Bowel Dis. 2012 Aug;18(8):1399-410. doi: 10.1002/ibd.22853. Epub 2012 Jan 4.


Early patient stratification and predictive biomarkers in drug discovery and development: a case study of ulcerative colitis anti-TNF therapy.

Laifenfeld D, Drubin DA, Catlett NL, Park JS, Van Hooser AA, Frushour BP, de Graaf D, Fryburg DA, Deehan R.

Adv Exp Med Biol. 2012;736:645-53. doi: 10.1007/978-1-4419-7210-1_38.


A network-based approach to quantifying the impact of biologically active substances.

Hoeng J, Deehan R, Pratt D, Martin F, Sewer A, Thomson TM, Drubin DA, Waters CA, de Graaf D, Peitsch MC.

Drug Discov Today. 2012 May;17(9-10):413-8. doi: 10.1016/j.drudis.2011.11.008. Epub 2011 Dec 2. No abstract available.


A computable cellular stress network model for non-diseased pulmonary and cardiovascular tissue.

Schlage WK, Westra JW, Gebel S, Catlett NL, Mathis C, Frushour BP, Hengstermann A, Van Hooser A, Poussin C, Wong B, Lietz M, Park J, Drubin D, Veljkovic E, Peitsch MC, Hoeng J, Deehan R.

BMC Syst Biol. 2011 Oct 19;5:168. doi: 10.1186/1752-0509-5-168.


Construction of a computable cell proliferation network focused on non-diseased lung cells.

Westra JW, Schlage WK, Frushour BP, Gebel S, Catlett NL, Han W, Eddy SF, Hengstermann A, Matthews AL, Mathis C, Lichtner RB, Poussin C, Talikka M, Veljkovic E, Van Hooser AA, Wong B, Maria MJ, Peitsch MC, Deehan R, Hoeng J.

BMC Syst Biol. 2011 Jul 2;5:105. doi: 10.1186/1752-0509-5-105.


Centromere glue provides spindle cue.

Deehan R, Heald R.

Cell. 2004 Sep 3;118(5):529-30. Review.


The condensin complex is required for proper spindle assembly and chromosome segregation in Xenopus egg extracts.

Wignall SM, Deehan R, Maresca TJ, Heald R.

J Cell Biol. 2003 Jun 23;161(6):1041-51.


Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules.

Verhey KJ, Meyer D, Deehan R, Blenis J, Schnapp BJ, Rapoport TA, Margolis B.

J Cell Biol. 2001 Mar 5;152(5):959-70.


Preoperative patient teaching. Producing a video account.

Barrett JB, Deehan RM.

AORN J. 1989 Sep;50(3):602-3, 605, 607-8. No abstract available.


The influence of arterial pH control on the cardiotoxicity of isoprenaline in hypoxic dogs [proceedings].

Deehan R, Swanton JG.

J Pharm Pharmacol. 1979 Dec;31 Suppl:38P. No abstract available.


The influence of hypoxia and hypercapnia on the cardiotoxicity of isoprenaline in dogs [proceedings].

Deehan R, Swanton JG.

J Pharm Pharmacol. 1978 Dec;30 Suppl:57P. No abstract available.

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