Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 236

1.

Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors.

Van der Perren A, Toelen J, Casteels C, Macchi F, Van Rompuy AS, Sarre S, Casadei N, Nuber S, Himmelreich U, Osorio Garcia MI, Michotte Y, D'Hooge R, Bormans G, Van Laere K, Gijsbers R, Van den Haute C, Debyser Z, Baekelandt V.

Neurobiol Aging. 2014 Dec 17. pii: S0197-4580(14)00786-6. doi: 10.1016/j.neurobiolaging.2014.11.015. [Epub ahead of print]

PMID:
25599874
[PubMed - as supplied by publisher]
2.

Host factors for retroviral integration site selection.

Debyser Z, Christ F, De Rijck J, Gijsbers R.

Trends Biochem Sci. 2015 Feb;40(2):108-116. doi: 10.1016/j.tibs.2014.12.001. Epub 2014 Dec 31. Review.

PMID:
25555456
[PubMed - as supplied by publisher]
3.

HIV-1 integrase variants retarget viral integration and are associated with disease progression in a chronic infection cohort.

Demeulemeester J, Vets S, Schrijvers R, Madlala P, De Maeyer M, De Rijck J, Ndung'u T, Debyser Z, Gijsbers R.

Cell Host Microbe. 2014 Nov 12;16(5):651-62. doi: 10.1016/j.chom.2014.09.016. Epub 2014 Nov 12.

PMID:
25525795
[PubMed - in process]
4.

Noninvasive bioluminescence imaging of α-synuclein oligomerization in mouse brain using split firefly luciferase reporters.

Aelvoet SA, Ibrahimi A, Macchi F, Gijsbers R, Van den Haute C, Debyser Z, Baekelandt V.

J Neurosci. 2014 Dec 3;34(49):16518-32. doi: 10.1523/JNEUROSCI.4933-13.2014.

PMID:
25471588
[PubMed - in process]
5.

Design and discovery of 5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide inhibitors of HIV-1 integrase.

Zhang D, Debnath B, Yu S, Sanchez TW, Christ F, Liu Y, Debyser Z, Neamati N, Zhao G.

Bioorg Med Chem. 2014 Oct 1;22(19):5446-53. doi: 10.1016/j.bmc.2014.07.036. Epub 2014 Jul 30.

PMID:
25150089
[PubMed - in process]
6.

BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements.

El Ashkar S, De Rijck J, Demeulemeester J, Vets S, Madlala P, Cermakova K, Debyser Z, Gijsbers R.

Mol Ther Nucleic Acids. 2014 Jul 29;3:e179. doi: 10.1038/mtna.2014.33.

PMID:
25072693
[PubMed]
Free PMC Article
7.

The HIV-1 integrase mutant R263A/K264A is 2-fold defective for TRN-SR2 binding and viral nuclear import.

De Houwer S, Demeulemeester J, Thys W, Rocha S, Dirix L, Gijsbers R, Christ F, Debyser Z.

J Biol Chem. 2014 Sep 5;289(36):25351-61. doi: 10.1074/jbc.M113.533281. Epub 2014 Jul 25.

PMID:
25063804
[PubMed - in process]
8.

Structure of transportin SR2, a karyopherin involved in human disease, in complex with Ran.

Tsirkone VG, Beutels KG, Demeulemeester J, Debyser Z, Christ F, Strelkov SV.

Acta Crystallogr F Struct Biol Commun. 2014 Jun;70(Pt 6):723-9. doi: 10.1107/S2053230X14009492. Epub 2014 May 24.

PMID:
24915079
[PubMed - in process]
9.

Switching STRATEGIES in HIV treatment.

Schrijvers R, Debyser Z.

Lancet Infect Dis. 2014 Jul;14(7):537-40. doi: 10.1016/S1473-3099(14)70743-1. Epub 2014 Jun 5. No abstract available. Erratum in: Lancet Infect Dis. 2014 Jul;14(7):548.

PMID:
24908549
[PubMed - indexed for MEDLINE]
10.

4-Substituted 2-Hydroxyisoquinoline-1,3(2H,4H)-diones as a Novel Class of HIV-1 Integrase Inhibitors.

Billamboz M, Suchaud V, Bailly F, Lion C, Demeulemeester J, Calmels C, Andréola ML, Christ F, Debyser Z, Cotelle P.

ACS Med Chem Lett. 2013 May 17;4(7):606-11. doi: 10.1021/ml400009t. eCollection 2013 Jul 11.

PMID:
24900718
[PubMed]
Free PMC Article
11.

Bioluminescence imaging of stroke-induced endogenous neural stem cell response.

Vandeputte C, Reumers V, Aelvoet SA, Thiry I, De Swaef S, Van den Haute C, Pascual-Brazo J, Farr TD, Vande Velde G, Hoehn M, Himmelreich U, Van Laere K, Debyser Z, Gijsbers R, Baekelandt V.

Neurobiol Dis. 2014 Sep;69:144-55. doi: 10.1016/j.nbd.2014.05.014. Epub 2014 May 27.

PMID:
24878507
[PubMed - in process]
12.

Investigation of a novel series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as human immunodeficiency virus type 1 integrase inhibitors.

Suchaud V, Bailly F, Lion C, Calmels C, Andréola ML, Christ F, Debyser Z, Cotelle P.

J Med Chem. 2014 Jun 12;57(11):4640-60. doi: 10.1021/jm500109z. Epub 2014 May 14.

PMID:
24793360
[PubMed - indexed for MEDLINE]
13.

Optimization of multimodal imaging of mesenchymal stem cells using the human sodium iodide symporter for PET and Cerenkov luminescence imaging.

Wolfs E, Holvoet B, Gijsbers R, Casteels C, Roberts SJ, Struys T, Maris M, Ibrahimi A, Debyser Z, Van Laere K, Verfaillie CM, Deroose CM.

PLoS One. 2014 Apr 18;9(4):e94833. doi: 10.1371/journal.pone.0094833. eCollection 2014.

PMID:
24747914
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Diketoacid chelating ligands as dual inhibitors of HIV-1 integration process.

Rogolino D, Carcelli M, Compari C, De Luca L, Ferro S, Fisicaro E, Rispoli G, Neamati N, Debyser Z, Christ F, Chimirri A.

Eur J Med Chem. 2014 May 6;78:425-30. doi: 10.1016/j.ejmech.2014.03.070. Epub 2014 Mar 25.

PMID:
24704615
[PubMed - indexed for MEDLINE]
15.

LEDGINs, non-catalytic site inhibitors of HIV-1 integrase: a patent review (2006 - 2014).

Demeulemeester J, Chaltin P, Marchand A, De Maeyer M, Debyser Z, Christ F.

Expert Opin Ther Pat. 2014 Jun;24(6):609-32. doi: 10.1517/13543776.2014.898753. Epub 2014 Mar 25.

PMID:
24666332
[PubMed - in process]
16.

HIV virions as nanoscopic test tubes for probing oligomerization of the integrase enzyme.

Borrenberghs D, Thys W, Rocha S, Demeulemeester J, Weydert C, Dedecker P, Hofkens J, Debyser Z, Hendrix J.

ACS Nano. 2014 Apr 22;8(4):3531-45. doi: 10.1021/nn406615v. Epub 2014 Apr 2.

PMID:
24654558
[PubMed - in process]
17.

Structure, mechanics, and binding mode heterogeneity of LEDGF/p75-DNA nucleoprotein complexes revealed by scanning force microscopy.

Vanderlinden W, Lipfert J, Demeulemeester J, Debyser Z, De Feyter S.

Nanoscale. 2014 May 7;6(9):4611-9. doi: 10.1039/c4nr00022f.

PMID:
24632996
[PubMed - in process]
18.

A new potential approach to block HIV-1 replication via protein-protein interaction and strand-transfer inhibition.

Ferro S, De Luca L, Lo Surdo G, Morreale F, Christ F, Debyser Z, Gitto R, Chimirri A.

Bioorg Med Chem. 2014 Apr 1;22(7):2269-79. doi: 10.1016/j.bmc.2014.02.012. Epub 2014 Feb 20.

PMID:
24618511
[PubMed - indexed for MEDLINE]
19.

Immunological ignorance allows long-term gene expression after perinatal recombinant adeno-associated virus-mediated gene transfer to murine airways.

Carlon MS, Vidović D, Dooley J, da Cunha MM, Maris M, Lampi Y, Toelen J, Van den Haute C, Baekelandt V, Deprest J, Verbeken E, Liston A, Gijsbers R, Debyser Z.

Hum Gene Ther. 2014 Jun;25(6):517-28. doi: 10.1089/hum.2013.196. Epub 2014 Mar 26.

PMID:
24548076
[PubMed - in process]
20.

Rational design of LEDGINs as first allosteric integrase inhibitors for the treatment of HIV infection.

Desimmie BA, Demeulemeester J, Christ F, Debyser Z.

Drug Discov Today Technol. 2013 Dec;10(4):e517-22. doi: 10.1016/j.ddtec.2012.10.002. Review.

PMID:
24451643
[PubMed - indexed for MEDLINE]
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk