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Items: 1 to 20 of 257

1.

Lessons Learned: HIV Points the Way Towards Precision Treatment of Mixed-Lineage Leukemia.

Cermakova K, Weydert C, Christ F, De Rijck J, Debyser Z.

Trends Pharmacol Sci. 2016 Jun 9. pii: S0165-6147(16)30036-0. doi: 10.1016/j.tips.2016.05.005. [Epub ahead of print] Review.

PMID:
27290878
2.

Preclinical evaluation of a P2X7 receptor selective radiotracer: PET studies in a rat model with local overexpression of the human P2X7 receptor and in non-human primates.

Ory D, Celen S, Gijsbers R, Van Den Haute C, Postnov A, Koole M, Vandeputte C, Andrés JI, De Angelis M, Langlois X, Bhattacharya A, Schmidt M, Alcazar J, Vanduffel W, Letavic MA, Van Laere K, Verbruggen A, Debyser Z, Bormans G.

J Nucl Med. 2016 May 19. pii: jnumed.115.169995. [Epub ahead of print]

PMID:
27199364
3.

2-hydroxyisoquinoline-1,3(2H,4H)-diones (HIDs) as human immunodeficiency virus type 1 integrase inhibitors: Influence of the alkylcarboxamide substitution of position 4.

Billamboz M, Suchaud V, Bailly F, Lion C, Andréola ML, Christ F, Debyser Z, Cotelle P.

Eur J Med Chem. 2016 Jul 19;117:256-68. doi: 10.1016/j.ejmech.2016.03.083. Epub 2016 Mar 28.

PMID:
27105029
4.

Comparative Analysis of HIV-1 and Murine Leukemia Virus Three-Dimensional Nuclear Distributions.

Quercioli V, Di Primio C, Casini A, Mulder LC, Vranckx LS, Borrenberghs D, Gijsbers R, Debyser Z, Cereseto A.

J Virol. 2016 Apr 29;90(10):5205-9. doi: 10.1128/JVI.03188-15. Print 2016 May 15.

PMID:
26962222
5.

Serotype-dependent transduction efficiencies of recombinant adeno-associated viral vectors in monkey neocortex.

Gerits A, Vancraeyenest P, Vreysen S, Laramée ME, Michiels A, Gijsbers R, Van den Haute C, Moons L, Debyser Z, Baekelandt V, Arckens L, Vanduffel W.

Neurophotonics. 2015 Jul;2(3):031209. doi: 10.1117/1.NPh.2.3.031209. Epub 2015 Oct 1.

PMID:
26839901
6.

An integrated multi-electrode-optrode array for in vitro optogenetics.

Welkenhuysen M, Hoffman L, Luo Z, De Proft A, Van den Haute C, Baekelandt V, Debyser Z, Gielen G, Puers R, Braeken D.

Sci Rep. 2016 Feb 2;6:20353. doi: 10.1038/srep20353.

7.

HIV-1 integrase inhibition: looking at cofactor interactions.

Christ F, Debyser Z.

Future Med Chem. 2015 Dec;7(18):2407-10. doi: 10.4155/fmc.15.162. Epub 2015 Dec 15. No abstract available.

8.

High-content analysis of α-synuclein aggregation and cell death in a cellular model of Parkinson's disease.

Macchi F, Deleersnijder A, Van den Haute C, Munck S, Pottel H, Michiels A, Debyser Z, Gerard M, Baekelandt V.

J Neurosci Methods. 2016 Mar 1;261:117-27. doi: 10.1016/j.jneumeth.2015.11.009. Epub 2015 Nov 24.

PMID:
26620202
9.

Noninvasive Imaging Reveals Stable Transgene Expression in Mouse Airways After Delivery of a Nonintegrating Recombinant Adeno-Associated Viral Vector.

Vidović D, Gijsbers R, Jimenez AQ, Dooley J, Van den Haute C, Van der Perren A, Liston A, Baekelandt V, Debyser Z, Carlon MS.

Hum Gene Ther. 2016 Jan;27(1):60-71. doi: 10.1089/hum.2015.109. Epub 2015 Dec 21.

PMID:
26567984
10.

rAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice.

Vidović D, Carlon MS, da Cunha MF, Dekkers JF, Hollenhorst MI, Bijvelds MJ, Ramalho AS, Van den Haute C, Ferrante M, Baekelandt V, Janssens HM, De Boeck K, Sermet-Gaudelus I, de Jonge HR, Gijsbers R, Beekman JM, Edelman A, Debyser Z.

Am J Respir Crit Care Med. 2016 Feb 1;193(3):288-98. doi: 10.1164/rccm.201505-0914OC.

PMID:
26509335
11.

Kuwanon-L as a New Allosteric HIV-1 Integrase Inhibitor: Molecular Modeling and Biological Evaluation.

Esposito F, Tintori C, Martini R, Christ F, Debyser Z, Ferrarese R, Cabiddu G, Corona A, Ceresola ER, Calcaterra A, Iovine V, Botta B, Clementi M, Canducci F, Botta M, Tramontano E.

Chembiochem. 2015 Nov;16(17):2507-12. doi: 10.1002/cbic.201500385. Epub 2015 Oct 26.

PMID:
26360521
12.

Targeting Virus-host Interactions of HIV Replication.

Weydert C, Rijck JD, Christ F, Debyser Z.

Curr Top Med Chem. 2016;16(10):1167-90.

PMID:
26324041
13.

Retroviral integration: Site matters: Mechanisms and consequences of retroviral integration site selection.

Demeulemeester J, De Rijck J, Gijsbers R, Debyser Z.

Bioessays. 2015 Nov;37(11):1202-14. doi: 10.1002/bies.201500051. Epub 2015 Aug 21. Review.

PMID:
26293289
14.

Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif.

Tesina P, Čermáková K, Hořejší M, Procházková K, Fábry M, Sharma S, Christ F, Demeulemeester J, Debyser Z, De Rijck J, Veverka V, Řezáčová P.

Nat Commun. 2015 Aug 6;6:7968. doi: 10.1038/ncomms8968.

PMID:
26245978
15.

PET imaging of TSPO in a rat model of local neuroinflammation induced by intracerebral injection of lipopolysaccharide.

Ory D, Planas A, Dresselaers T, Gsell W, Postnov A, Celen S, Casteels C, Himmelreich U, Debyser Z, Van Laere K, Verbruggen A, Bormans G.

Nucl Med Biol. 2015 Oct;42(10):753-61. doi: 10.1016/j.nucmedbio.2015.06.010. Epub 2015 Jun 23.

PMID:
26220690
16.

Discovery of N-aryl-naphthylamines as in vitro inhibitors of the interaction between HIV integrase and the cofactor LEDGF/p75.

Cuzzucoli Crucitti G, Pescatori L, Messore A, Madia VN, Pupo G, Saccoliti F, Scipione L, Tortorella S, Di Leva FS, Cosconati S, Novellino E, Debyser Z, Christ F, Costi R, Di Santo R.

Eur J Med Chem. 2015 Aug 28;101:288-94. doi: 10.1016/j.ejmech.2015.06.036. Epub 2015 Jun 22.

PMID:
26150289
17.

Evaluation of the expression pattern of rAAV2/1, 2/5, 2/7, 2/8, and 2/9 serotypes with different promoters in the mouse visual cortex.

Scheyltjens I, Laramée ME, Van den Haute C, Gijsbers R, Debyser Z, Baekelandt V, Vreysen S, Arckens L.

J Comp Neurol. 2015 Oct 1;523(14):2019-42. doi: 10.1002/cne.23819. Epub 2015 Jun 19.

PMID:
26012540
18.

Optimization of rhodanine scaffold for the development of protein-protein interaction inhibitors.

Ferro S, De Luca L, Agharbaoui FE, Christ F, Debyser Z, Gitto R.

Bioorg Med Chem. 2015 Jul 1;23(13):3208-14. doi: 10.1016/j.bmc.2015.04.072. Epub 2015 May 2.

PMID:
25999203
19.

HIV-1 IN/Pol recruits LEDGF/p75 into viral particles.

Desimmie BA, Weydert C, Schrijvers R, Vets S, Demeulemeester J, Proost P, Paron I, De Rijck J, Mast J, Bannert N, Gijsbers R, Christ F, Debyser Z.

Retrovirology. 2015 Feb 12;12:16. doi: 10.1186/s12977-014-0134-4.

20.

Five-drug antiretroviral therapy for primary HIV infection?

Debyser Z, Schrijvers R.

Lancet Infect Dis. 2015 Apr;15(4):362-3. doi: 10.1016/S1473-3099(14)71014-X. Epub 2015 Feb 18. No abstract available.

PMID:
25701559
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