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Items: 1 to 20 of 113

1.

Suppression of Ser/Thr phosphatase 4 (PP4C/PPP4C) mimics a novel post-mitotic action of fostriecin, producing mitotic slippage followed by tetraploid cell death.

Theobald B, Bonness K, Musiyenko A, Andrews JF, Urban G, Huang X, Dean NM, Honkanen RE.

Mol Cancer Res. 2013 Aug;11(8):845-55. doi: 10.1158/1541-7786.MCR-13-0032. Epub 2013 May 13.

2.

Antisense inhibition of connective tissue growth factor (CTGF/CCN2) mRNA limits hypertrophic scarring without affecting wound healing in vivo.

Sisco M, Kryger ZB, O'Shaughnessy KD, Kim PS, Schultz GS, Ding XZ, Roy NK, Dean NM, Mustoe TA.

Wound Repair Regen. 2008 Sep-Oct;16(5):661-73. doi: 10.1111/j.1524-475X.2008.00416.x.

PMID:
19128261
3.

Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity.

Graff JR, Konicek BW, Vincent TM, Lynch RL, Monteith D, Weir SN, Schwier P, Capen A, Goode RL, Dowless MS, Chen Y, Zhang H, Sissons S, Cox K, McNulty AM, Parsons SH, Wang T, Sams L, Geeganage S, Douglass LE, Neubauer BL, Dean NM, Blanchard K, Shou J, Stancato LF, Carter JH, Marcusson EG.

J Clin Invest. 2007 Sep;117(9):2638-48.

4.

Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cells.

Kim Y, Yoon JW, Xiao X, Dean NM, Monia BP, Marcusson EG.

Cancer Res. 2007 Apr 15;67(8):3583-93.

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Regulation and targeting of Eg5, a mitotic motor protein in blast crisis CML: overcoming imatinib resistance.

Carter BZ, Mak DH, Shi Y, Schober WD, Wang RY, Konopleva M, Koller E, Dean NM, Andreeff M.

Cell Cycle. 2006 Oct;5(19):2223-9. Epub 2006 Oct 1.

PMID:
16969080
7.

Competition for RISC binding predicts in vitro potency of siRNA.

Koller E, Propp S, Murray H, Lima W, Bhat B, Prakash TP, Allerson CR, Swayze EE, Marcusson EG, Dean NM.

Nucleic Acids Res. 2006;34(16):4467-76. Epub 2006 Aug 31.

8.

Laparoscopic colposuspension for urinary incontinence in women.

Dean NM, Ellis G, Wilson PD, Herbison GP.

Cochrane Database Syst Rev. 2006 Jul 19;(3):CD002239. Review.

PMID:
16855989
9.
10.

Use of a chemically modified antisense oligonucleotide library to identify and validate Eg5 (kinesin-like 1) as a target for antineoplastic drug development.

Koller E, Propp S, Zhang H, Zhao C, Xiao X, Chang M, Hirsch SA, Shepard PJ, Koo S, Murphy C, Glazer RI, Dean NM.

Cancer Res. 2006 Feb 15;66(4):2059-66.

11.

Defining the transcriptome of accelerated and replicatively senescent keratinocytes reveals links to differentiation, interferon signaling, and Notch related pathways.

Perera RJ, Koo S, Bennett CF, Dean NM, Gupta N, Qin JZ, Nickoloff BJ.

J Cell Biochem. 2006 May 15;98(2):394-408.

PMID:
16440318
12.

Identification of novel PPARgamma target genes in primary human adipocytes.

Perera RJ, Marcusson EG, Koo S, Kang X, Kim Y, White N, Dean NM.

Gene. 2006 Mar 15;369:90-9. Epub 2005 Dec 27.

PMID:
16380219
13.

Protein phosphatase 5 is required for ATR-mediated checkpoint activation.

Zhang J, Bao S, Furumai R, Kucera KS, Ali A, Dean NM, Wang XF.

Mol Cell Biol. 2005 Nov;25(22):9910-9.

14.
15.

Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs.

Sun Y, Koo S, White N, Peralta E, Esau C, Dean NM, Perera RJ.

Nucleic Acids Res. 2004 Dec 22;32(22):e188.

16.

MicroRNA-143 regulates adipocyte differentiation.

Esau C, Kang X, Peralta E, Hanson E, Marcusson EG, Ravichandran LV, Sun Y, Koo S, Perera RJ, Jain R, Dean NM, Freier SM, Bennett CF, Lollo B, Griffey R.

J Biol Chem. 2004 Dec 10;279(50):52361-5. Epub 2004 Oct 25.

17.

Setting sights on the treatment of ocular angiogenesis using antisense oligonucleotides.

Henry SP, Marcusson EG, Vincent TM, Dean NM.

Trends Pharmacol Sci. 2004 Oct;25(10):523-7. Review.

PMID:
15380936
18.

Constitutive over expression of serine/threonine protein phosphatase 5 (PP5) augments estrogen-dependent tumor growth in mice.

Golden T, Aragon IV, Zhou G, Cooper SR, Dean NM, Honkanen RE.

Cancer Lett. 2004 Nov 8;215(1):95-100.

PMID:
15374638
19.

Use of antisense oligonucleotides in functional genomics and target validation.

Ravichandran LV, Dean NM, Marcusson EG.

Oligonucleotides. 2004 Spring;14(1):49-64. Review.

PMID:
15104896
20.
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