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Results: 1 to 20 of 78


Long-term use of ticagrelor in patients with prior myocardial infarction.

Bonaca MP, Bhatt DL, Cohen M, Steg PG, Storey RF, Jensen EC, Magnani G, Bansilal S, Fish MP, Im K, Bengtsson O, Oude Ophuis T, Budaj A, Theroux P, Ruda M, Hamm C, Goto S, Spinar J, Nicolau JC, Kiss RG, Murphy SA, Wiviott SD, Held P, Braunwald E, Sabatine MS; PEGASUS-TIMI 54 Steering Committee and Investigators.

N Engl J Med. 2015 May 7;372(19):1791-800. doi: 10.1056/NEJMoa1500857. Epub 2015 Mar 14.


In-hospital management and outcomes of acute coronary syndromes in relation to prior history of heart failure.

Zhang H, Goodman SG, Yan RT, Steg PG, Kornder JM, Gyenes GT, Grondin FR, Brieger D, DeYoung JP, Gallo R, Yan AT; Canadian GRACE and CANRACE Investigators.

Eur Heart J Acute Cardiovasc Care. 2015 Mar 12. pii: 2048872615574109. [Epub ahead of print]


Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma.

Luykx JJ, Bakker SC, Visser WF, Verhoeven-Duif N, Buizer-Voskamp JE, den Heijer JM, Boks MP, Sul JH, Eskin E, Ori AP, Cantor RM, Vorstman J, Strengman E, DeYoung J, Kappen TH, Pariama E, van Dongen EP, Borgdorff P, Bruins P, de Koning TJ, Kahn RS, Ophoff RA.

Mol Psychiatry. 2015 Feb 10. doi: 10.1038/mp.2014.190. [Epub ahead of print]


Spironolactone for heart failure with preserved ejection fraction.

Pitt B, Pfeffer MA, Assmann SF, Boineau R, Anand IS, Claggett B, Clausell N, Desai AS, Diaz R, Fleg JL, Gordeev I, Harty B, Heitner JF, Kenwood CT, Lewis EF, O'Meara E, Probstfield JL, Shaburishvili T, Shah SJ, Solomon SD, Sweitzer NK, Yang S, McKinlay SM; TOPCAT Investigators.

N Engl J Med. 2014 Apr 10;370(15):1383-92. doi: 10.1056/NEJMoa1313731.


Seasonal variation of serotonin turnover in human cerebrospinal fluid, depressive symptoms and the role of the 5-HTTLPR.

Luykx JJ, Bakker SC, van Geloven N, Eijkemans MJ, Horvath S, Lentjes E, Boks MP, Strengman E, DeYoung J, Buizer-Voskamp JE, Cantor RM, Lu A, van Dongen EP, Borgdorff P, Bruins P, Kahn RS, Ophoff RA.

Transl Psychiatry. 2013 Oct 8;3:e311. doi: 10.1038/tp.2013.84.


Prognostic significance of presenting blood pressure in non-ST-segment elevation acute coronary syndrome in relation to prior history of hypertension.

Lee D, Goodman SG, Fox KA, DeYoung JP, Lai CC, Bhatt DL, Huynh T, Yan RT, Gallo R, Steg PG, Yan AT.

Am Heart J. 2013 Oct;166(4):716-22. doi: 10.1016/j.ahj.2013.06.025. Epub 2013 Sep 4.


Use and timing of coronary angiography and associated in-hospital outcomes in Canadian non-ST-segment elevation myocardial infarction patients: insights from the Canadian Global Registry of Acute Coronary Events.

Gyenes GT, Yan AT, Tan M, Welsh RC, Fox KA, Grondin FR, Deyoung JP, Rose BF, Gallo R, Kornder JM, Wong GC, Goodman SG; Canadian Global Registry of Acute Coronary Events (GRACE/GRACE(2)); Canadian Registry of Acute Coronary Events (CANRACE) Investigators.

Can J Cardiol. 2013 Nov;29(11):1429-35. doi: 10.1016/j.cjca.2013.04.035. Epub 2013 Jul 30.


Methodology of clinical research in rare diseases: development of a research program in juvenile neuronal ceroid lipofuscinosis (JNCL) via creation of a patient registry and collaboration with patient advocates.

de Blieck EA, Augustine EF, Marshall FJ, Adams H, Cialone J, Dure L, Kwon JM, Newhouse N, Rose K, Rothberg PG, Vierhile A, Mink JW; Batten Study Group.

Contemp Clin Trials. 2013 Jul;35(2):48-54. doi: 10.1016/j.cct.2013.04.004. Epub 2013 Apr 26.


Treatment and outcomes of non-ST elevation acute coronary syndromes in relation to burden of pre-existing vascular disease.

Mohareb M, Goodman SG, Yan RT, Bhatt DL, Elbarouni B, Deyoung JP, Gallo R, Kornder JM, Welsh RC, Saposnik G, Rose B, Wong GC, Grondin FR, Yan AT; Canadian GRACE/GRACE2/CANRACE Investigators.

Int J Cardiol. 2013 Oct 3;168(3):2720-5. doi: 10.1016/j.ijcard.2013.03.020. Epub 2013 Apr 17.


Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.

Luykx JJ, Bakker SC, Lentjes E, Neeleman M, Strengman E, Mentink L, DeYoung J, de Jong S, Sul JH, Eskin E, van Eijk K, van Setten J, Buizer-Voskamp JE, Cantor RM, Lu A, van Amerongen M, van Dongen EP, Keijzers P, Kappen T, Borgdorff P, Bruins P, Derks EM, Kahn RS, Ophoff RA.

Mol Psychiatry. 2014 Feb;19(2):228-34. doi: 10.1038/mp.2012.183. Epub 2013 Jan 15.


A non-human primate system for large-scale genetic studies of complex traits.

Jasinska AJ, Lin MK, Service S, Choi OW, DeYoung J, Grujic O, Kong SY, Jung Y, Jorgensen MJ, Fairbanks LA, Turner T, Cantor RM, Wasserscheid J, Dewar K, Warren W, Wilson RK, Weinstock G, Jentsch JD, Freimer NB.

Hum Mol Genet. 2012 Aug 1;21(15):3307-16. doi: 10.1093/hmg/dds160. Epub 2012 May 3.


Reperfusion strategies and outcomes of ST-segment elevation myocardial infarction patients in Canada: observations from the Global Registry of Acute Coronary Events (GRACE) and the Canadian Registry of Acute Coronary Events (CANRACE).

Czarnecki A, Welsh RC, Yan RT, DeYoung JP, Gallo R, Rose B, Grondin FR, Kornder JM, Wong GC, Fox KA, Gore JM, Goodman SG, Yan AT; Global Registry of Acute Coronary Events (GRACE/GRACE2); Canadian Registry of Coronary Events (CANRACE) Investigators.

Can J Cardiol. 2012 Jan-Feb;28(1):40-7. doi: 10.1016/j.cjca.2011.09.011. Epub 2011 Nov 29.


The association between prior use of aspirin and/or warfarin and the in-hospital management and outcomes in patients presenting with acute coronary syndromes: insights from the Global Registry of Acute Coronary Events (GRACE).

Amad H, Yan AT, Yan RT, Huynh T, Gore JM, Montalescot G, DeYoung JP, Gallo R, Rose B, Steg PG, Goodman SG; Canadian Global Registry of Acute Coronary Events (GRACE) Investigators.

Can J Cardiol. 2012 Jan-Feb;28(1):48-53. doi: 10.1016/j.cjca.2011.09.003. Epub 2011 Nov 23.


Use of clopidogrel post-coronary artery bypass surgery in canadian patients with acute coronary syndromes.

Krimly A, Yan RT, Yan AT, DeYoung JP, Gallo R, Steg G, Eikelboom J, Gore JM, Fox KA, Fitchett D, Quantz MA, Goodman SG.

Can J Cardiol. 2011 Nov-Dec;27(6):711-5. doi: 10.1016/j.cjca.2011.06.003. Epub 2011 Aug 27.


Temporal changes in the management and outcome of Canadian diabetic patients hospitalized for non-ST-elevation acute coronary syndromes.

Elbarouni B, Ismaeil N, Yan RT, Fox KA, Connelly KA, Baer C, DeYoung JP, Gallo R, Ramanathan K, Pesant Y, Leiter LA, Goodman SG, Yan AT.

Am Heart J. 2011 Aug;162(2):347-355.e1. doi: 10.1016/j.ahj.2011.05.020. Epub 2011 Jul 20.


Persistent lipid abnormalities in statin-treated patients with diabetes mellitus in Europe and Canada: results of the Dyslipidaemia International Study.

Leiter LA, Lundman P, da Silva PM, Drexel H, Jünger C, Gitt AK; DYSIS investigators.

Diabet Med. 2011 Nov;28(11):1343-51. doi: 10.1111/j.1464-5491.2011.03360.x.


Irbesartan in patients with atrial fibrillation.

ACTIVE I Investigators, Yusuf S, Healey JS, Pogue J, Chrolavicius S, Flather M, Hart RG, Hohnloser SH, Joyner CD, Pfeffer MA, Connolly SJ.

N Engl J Med. 2011 Mar 10;364(10):928-38. doi: 10.1056/NEJMoa1008816.


Has the ClOpidogrel and Metoprolol in Myocardial Infarction Trial (COMMIT) of early β-blocker use in acute coronary syndromes impacted on clinical practice in Canada? Insights from the Global Registry of Acute Coronary Events (GRACE).

Edwards J, Goodman SG, Yan RT, Welsh RC, Kornder JM, Deyoung JP, Chauret D, Picard JP, Eagle KA, Yan AT.

Am Heart J. 2011 Feb;161(2):291-7. doi: 10.1016/j.ahj.2010.10.034.


Prevalence of dyslipidemia in statin-treated patients in Canada: results of the DYSlipidemia International Study (DYSIS).

Goodman SG, Langer A, Bastien NR, McPherson R, Francis GA, Genest JJ Jr, Leiter LA; DYSIS Canadian Investigators.

Can J Cardiol. 2010 Nov;26(9):e330-5.


Cost savings from dose rounding of biologic anticancer agents in adults.

Winger BJ, Clements EA, DeYoung JL, O'Rourke TJ, Claypool DL, Vachon S, VanDyke TH, Zimmer-Young J, Kintzel PE.

J Oncol Pharm Pract. 2011 Sep;17(3):246-51. doi: 10.1177/1078155210366171. Epub 2010 Mar 23.

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