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Results: 1 to 20 of 78


IL-13 Stimulates Proliferation and Expression of Mucin and Immunomodulatory Genes in Cultured Conjunctival Goblet Cells.

Tukler Henriksson J, Coursey TG, Corry DB, De Paiva CS, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2015 Jul 1;56(8):4186-97. doi: 10.1167/iovs.14-15496.


Altered balance of interleukin-13/interferon-gamma contributes to lacrimal gland destruction and secretory dysfunction in CD25 knockout model of Sjögren's syndrome.

Bian F, Barbosa FL, Corrales RM, Pelegrino FS, Volpe EA, Pflugfelder SC, de Paiva CS.

Arthritis Res Ther. 2015 Mar 10;17:53. doi: 10.1186/s13075-015-0582-9.


Effects of Dry Eye Therapies on Environmentally Induced Ocular Surface Disease.

Moore QL, De Paiva CS, Pflugfelder SC.

Am J Ophthalmol. 2015 Jul;160(1):135-142.e1. doi: 10.1016/j.ajo.2015.04.008. Epub 2015 Apr 11.


Macrophage Phenotype in the Ocular Surface of Experimental Murine Dry Eye Disease.

You IC, Coursey TG, Bian F, Barbosa FL, de Paiva CS, Pflugfelder SC.

Arch Immunol Ther Exp (Warsz). 2015 Mar 13. [Epub ahead of print]


Age-Related Conjunctival Disease in the C57BL/6.NOD-Aec1Aec2 Mouse Model of Sjögren Syndrome Develops Independent of Lacrimal Dysfunction.

You IC, Bian F, Volpe EA, de Paiva CS, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2015 Apr 1;56(4):2224-33. doi: 10.1167/iovs.14-15668.


Desiccating stress-induced chemokine expression in the epithelium is dependent on upregulation of NKG2D/RAE-1 and release of IFN-γ in experimental dry eye.

Coursey TG, Bohat R, Barbosa FL, Pflugfelder SC, de Paiva CS.

J Immunol. 2014 Nov 15;193(10):5264-72. doi: 10.4049/jimmunol.1400016. Epub 2014 Oct 6.


Managing Sjögren's Syndrome and non-Sjögren Syndrome dry eye with anti-inflammatory therapy.

Coursey TG, de Paiva CS.

Clin Ophthalmol. 2014 Aug 4;8:1447-58. doi: 10.2147/OPTH.S35685. eCollection 2014. Review.


A potential link between bacterial pathogens and allergic conjunctivitis by dendritic cells.

Deng R, Su Z, Lu F, Zhang L, Lin J, Zhang X, de Paiva CS, Pflugfelder SC, Li DQ.

Exp Eye Res. 2014 Mar;120:118-26. doi: 10.1016/j.exer.2014.01.014. Epub 2014 Jan 29.


Effect of desiccating stress on mouse meibomian gland function.

Suhalim JL, Parfitt GJ, Xie Y, De Paiva CS, Pflugfelder SC, Shah TN, Potma EO, Brown DJ, Jester JV.

Ocul Surf. 2014 Jan;12(1):59-68. doi: 10.1016/j.jtos.2013.08.002. Epub 2013 Oct 18. Erratum in: Ocul Surf. 2014 Apr;12(2):159. De Pavia, Cintia S [corrected to De Paiva, Cintia S].


Ocular surface disease and dacryoadenitis in aging C57BL/6 mice.

McClellan AJ, Volpe EA, Zhang X, Darlington GJ, Li DQ, Pflugfelder SC, de Paiva CS.

Am J Pathol. 2014 Mar;184(3):631-43. doi: 10.1016/j.ajpath.2013.11.019. Epub 2014 Jan 3.


Topical interferon-gamma neutralization prevents conjunctival goblet cell loss in experimental murine dry eye.

Zhang X, De Paiva CS, Su Z, Volpe EA, Li DQ, Pflugfelder SC.

Exp Eye Res. 2014 Jan;118:117-24. doi: 10.1016/j.exer.2013.11.011. Epub 2013 Dec 4.


Chemokine receptors CCR6 and CXCR3 are necessary for CD4(+) T cell mediated ocular surface disease in experimental dry eye disease.

Coursey TG, Gandhi NB, Volpe EA, Pflugfelder SC, de Paiva CS.

PLoS One. 2013 Nov 4;8(11):e78508. doi: 10.1371/journal.pone.0078508. eCollection 2013.


CD8⁺ cells regulate the T helper-17 response in an experimental murine model of Sjögren syndrome.

Zhang X, Schaumburg CS, Coursey TG, Siemasko KF, Volpe EA, Gandhi NB, Li DQ, Niederkorn JY, Stern ME, Pflugfelder SC, de Paiva CS.

Mucosal Immunol. 2014 Mar;7(2):417-27. doi: 10.1038/mi.2013.61. Epub 2013 Sep 11.


T helper cytokines in dry eye disease.

Pflugfelder SC, Corrales RM, de Paiva CS.

Exp Eye Res. 2013 Dec;117:118-25. doi: 10.1016/j.exer.2013.08.013. Epub 2013 Sep 4. Review.


Dendritic cell-derived thrombospondin-1 is critical for the generation of the ocular surface Th17 response to desiccating stress.

Gandhi NB, Su Z, Zhang X, Volpe EA, Pelegrino FS, Rahman SA, Li DQ, Pflugfelder SC, de Paiva CS.

J Leukoc Biol. 2013 Dec;94(6):1293-301. doi: 10.1189/jlb.1012524. Epub 2013 Aug 27.


Factors predicting the ocular surface response to desiccating environmental stress.

Alex A, Edwards A, Hays JD, Kerkstra M, Shih A, de Paiva CS, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2013 May 7;54(5):3325-32. doi: 10.1167/iovs.12-11322.


Potential autocrine regulation of interleukin-33/ST2 signaling of dendritic cells in allergic inflammation.

Su Z, Lin J, Lu F, Zhang X, Zhang L, Gandhi NB, de Paiva CS, Pflugfelder SC, Li DQ.

Mucosal Immunol. 2013 Sep;6(5):921-30. doi: 10.1038/mi.2012.130. Epub 2013 Jan 9.


A native-like corneal construct using donor corneal stroma for tissue engineering.

Lin J, Yoon KC, Zhang L, Su Z, Lu R, Ma P, De Paiva CS, Pflugfelder SC, Li DQ.

PLoS One. 2012;7(11):e49571. doi: 10.1371/journal.pone.0049571. Epub 2012 Nov 15.


Morphologic alterations of the palpebral conjunctival epithelium in a dry eye model.

Henriksson JT, De Paiva CS, Farley W, Pflugfelder SC, Burns AR, Bergmanson JP.

Cornea. 2013 Apr;32(4):483-90. doi: 10.1097/ICO.0b013e318265682c.


Deletion of interferon-γ delays onset and severity of dacryoadenitis in CD25KO mice.

Pelegrino FS, Volpe EA, Gandhi NB, Li DQ, Pflugfelder SC, de Paiva CS.

Arthritis Res Ther. 2012 Nov 1;14(6):R234. doi: 10.1186/ar4077.

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