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Results: 1 to 20 of 46


Dissecting cancer evolution at the macro-heterogeneity and micro-heterogeneity scale.

Barber LJ, Davies MN, Gerlinger M.

Curr Opin Genet Dev. 2014 Dec 30;30C:1-6. doi: 10.1016/j.gde.2014.12.001. [Epub ahead of print] Review.


Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins.

Buil A, Brown AA, Lappalainen T, Viñuela A, Davies MN, Zheng HF, Richards JB, Glass D, Small KS, Durbin R, Spector TD, Dermitzakis ET.

Nat Genet. 2015 Jan;47(1):88-91. doi: 10.1038/ng.3162. Epub 2014 Dec 1.


Hypermethylation in the ZBTB20 gene is associated with major depressive disorder.

Davies MN, Krause L, Bell JT, Gao F, Ward KJ, Wu H, Lu H, Liu Y, Tsai PC, Collier DA, Murphy T, Dempster E, Mill J; UK Brain Expression Consortium, Battle A, Mostafavi S, Zhu X, Henders A, Byrne E, Wray NR, Martin NG, Spector TD, Wang J.

Genome Biol. 2014 Apr 2;15(4):R56. doi: 10.1186/gb-2014-15-4-r56.


Differential methylation of the TRPA1 promoter in pain sensitivity.

Bell JT, Loomis AK, Butcher LM, Gao F, Zhang B, Hyde CL, Sun J, Wu H, Ward K, Harris J, Scollen S, Davies MN, Schalkwyk LC, Mill J; MuTHER Consortium, Williams FM, Li N, Deloukas P, Beck S, McMahon SB, Wang J, John SL, Spector TD.

Nat Commun. 2014;5:2978. doi: 10.1038/ncomms3978.


Gene expression changes with age in skin, adipose tissue, blood and brain.

Glass D, Viñuela A, Davies MN, Ramasamy A, Parts L, Knowles D, Brown AA, Hedman AK, Small KS, Buil A, Grundberg E, Nica AC, Di Meglio P, Nestle FO, Ryten M; UK Brain Expression consortium; MuTHER consortium, Durbin R, McCarthy MI, Deloukas P, Dermitzakis ET, Weale ME, Bataille V, Spector TD.

Genome Biol. 2013 Jul 26;14(7):R75. doi: 10.1186/gb-2013-14-7-r75.


How are drug regimen changes during hospitalisation handled after discharge: a cohort study.

Viktil KK, Blix HS, Eek AK, Davies MN, Moger TA, Reikvam A.

BMJ Open. 2012 Nov 19;2(6). pii: e001461. doi: 10.1136/bmjopen-2012-001461. Print 2012.


Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood.

Davies MN, Volta M, Pidsley R, Lunnon K, Dixit A, Lovestone S, Coarfa C, Harris RA, Milosavljevic A, Troakes C, Al-Sarraj S, Dobson R, Schalkwyk LC, Mill J.

Genome Biol. 2012 Jun 15;13(6):R43. doi: 10.1186/gb-2012-13-6-r43.


Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility.

Muoio DM, Noland RC, Kovalik JP, Seiler SE, Davies MN, DeBalsi KL, Ilkayeva OR, Stevens RD, Kheterpal I, Zhang J, Covington JD, Bajpeyi S, Ravussin E, Kraus W, Koves TR, Mynatt RL.

Cell Metab. 2012 May 2;15(5):764-77. doi: 10.1016/j.cmet.2012.04.005.


Present perspectives on the automated classification of the G-protein coupled receptors (GPCRs) at the protein sequence level.

Davies MN, Gloriam DE, Secker A, Freitas AA, Timmis J, Flower DR.

Curr Top Med Chem. 2011;11(15):1994-2009. Review.


T-cell epitope prediction and immune complex simulation using molecular dynamics: state of the art and persisting challenges.

Flower DR, Phadwal K, Macdonald IK, Coveney PV, Davies MN, Wan S.

Immunome Res. 2010 Nov 3;6 Suppl 2:S4. doi: 10.1186/1745-7580-6-S2-S4.


Computer aided selection of candidate vaccine antigens.

Flower DR, Macdonald IK, Ramakrishnan K, Davies MN, Doytchinova IA.

Immunome Res. 2010 Nov 3;6 Suppl 2:S1. doi: 10.1186/1745-7580-6-S2-S1.


Gene set enrichment; a problem of pathways.

Davies MN, Meaburn EL, Schalkwyk LC.

Brief Funct Genomics. 2010 Dec;9(5-6):385-90. doi: 10.1093/bfgp/elq021. Epub 2010 Sep 22.


Activation and repression of glucose-stimulated ChREBP requires the concerted action of multiple domains within the MondoA conserved region.

Davies MN, O'Callaghan BL, Towle HC.

Am J Physiol Endocrinol Metab. 2010 Oct;299(4):E665-74. doi: 10.1152/ajpendo.00349.2010. Epub 2010 Aug 3.


Hierarchical classification of G-protein-coupled receptors with data-driven selection of attributes and classifiers.

Secker A, Davies MN, Freitas AA, Clark EB, Timmis J, Flower DR.

Int J Data Min Bioinform. 2010;4(2):191-210.


Allelic skewing of DNA methylation is widespread across the genome.

Schalkwyk LC, Meaburn EL, Smith R, Dempster EL, Jeffries AR, Davies MN, Plomin R, Mill J.

Am J Hum Genet. 2010 Feb 12;86(2):196-212. doi: 10.1016/j.ajhg.2010.01.014.


Toward the discovery of vaccine adjuvants: coupling in silico screening and in vitro analysis of antagonist binding to human and mouse CCR4 receptors.

Davies MN, Bayry J, Tchilian EZ, Vani J, Shaila MS, Forbes EK, Draper SJ, Beverley PC, Tough DF, Flower DR.

PLoS One. 2009 Nov 30;4(11):e8084. doi: 10.1371/journal.pone.0008084.


Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality.

Collier LS, Adams DJ, Hackett CS, Bendzick LE, Akagi K, Davies MN, Diers MD, Rodriguez FJ, Bender AM, Tieu C, Matise I, Dupuy AJ, Copeland NG, Jenkins NA, Hodgson JG, Weiss WA, Jenkins RB, Largaespada DA.

Cancer Res. 2009 Nov 1;69(21):8429-37. doi: 10.1158/0008-5472.CAN-09-1760. Epub 2009 Oct 20.


In silico identification of novel G protein coupled receptors.

Davies MN, Flower DR.

Methods Mol Biol. 2009;528:25-36. doi: 10.1007/978-1-60327-310-7_2.


To What Extent is Blood a Reasonable Surrogate for Brain in Gene Expression Studies: Estimation from Mouse Hippocampus and Spleen.

Davies MN, Lawn S, Whatley S, Fernandes C, Williams RW, Schalkwyk LC.

Front Neurosci. 2009 Oct 9;3:54. doi: 10.3389/neuro.15.002.2009. eCollection 2009.


GPCRTree: online hierarchical classification of GPCR function.

Davies MN, Secker A, Halling-Brown M, Moss DS, Freitas AA, Timmis J, Clark E, Flower DR.

BMC Res Notes. 2008 Aug 21;1:67. doi: 10.1186/1756-0500-1-67.

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