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Results: 1 to 20 of 30


Hypoxia regulates Toll-like receptor-9 expression and invasive function in human brain cancer cells in vitro.

Sandholm J, Tuomela J, Kauppila JH, Harris KW, Graves D, Selander KS.

Oncol Lett. 2014 Jul;8(1):266-274. Epub 2014 Apr 25.


Recognition and binding of human telomeric G-quadruplex DNA by unfolding protein 1.

Hudson JS, Ding L, Le V, Lewis E, Graves D.

Biochemistry. 2014 May 27;53(20):3347-56. doi: 10.1021/bi500351u. Epub 2014 May 15.


Collective effects in vortex movements in complex plasmas.

Schwabe M, Zhdanov S, Räth C, Graves DB, Thomas HM, Morfill GE.

Phys Rev Lett. 2014 Mar 21;112(11):115002. Epub 2014 Mar 19.


Addition of bases to the 5'-end of human telomeric DNA: influences on thermal stability and energetics of unfolding.

Hayden KL, Graves DE.

Molecules. 2014 Feb 21;19(2):2286-98. doi: 10.3390/molecules19022286.


DNA from dead cancer cells induces TLR9-mediated invasion and inflammation in living cancer cells.

Tuomela J, Sandholm J, Kaakinen M, Patel A, Kauppila JH, Ilvesaro J, Chen D, Harris KW, Graves D, Selander KS.

Breast Cancer Res Treat. 2013 Dec;142(3):477-87. doi: 10.1007/s10549-013-2762-0. Epub 2013 Nov 10.


Assessing helminth community structure and patterns in gizzard helminths of blue-winged teal (Anas discors).

Graves DW, Fedynich AM.

J Parasitol. 2013 Oct;99(5):748-51. doi: 10.1645/GE-3240.1. Epub 2013 Apr 10.


Short DNA sequences and bacterial DNA induce esophageal, gastric, and colorectal cancer cell invasion.

Kauppila JH, Karttunen TJ, Saarnio J, Nyberg P, Salo T, Graves DE, Lehenkari PP, Selander KS.

APMIS. 2013 Jun;121(6):511-22. doi: 10.1111/apm.12016. Epub 2012 Oct 22.


Low TLR9 expression defines an aggressive subtype of triple-negative breast cancer.

Tuomela J, Sandholm J, Karihtala P, Ilvesaro J, Vuopala KS, Kauppila JH, Kauppila S, Chen D, Pressey C, Härkönen P, Harris KW, Graves D, Auvinen PK, Soini Y, Jukkola-Vuorinen A, Selander KS.

Breast Cancer Res Treat. 2012 Sep;135(2):481-93. doi: 10.1007/s10549-012-2181-7. Epub 2012 Jul 31.


Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions.

Ketron AC, Denny WA, Graves DE, Osheroff N.

Biochemistry. 2012 Feb 28;51(8):1730-9. doi: 10.1021/bi201159b. Epub 2012 Feb 10.


Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance.

Aldred KJ, McPherson SA, Wang P, Kerns RJ, Graves DE, Turnbough CL Jr, Osheroff N.

Biochemistry. 2012 Jan 10;51(1):370-81. doi: 10.1021/bi2013905. Epub 2011 Dec 16.


Contributions of the D-Ring to the activity of etoposide against human topoisomerase IIα: potential interactions with DNA in the ternary enzyme--drug--DNA complex.

Pitts SL, Jablonksy MJ, Duca M, Dauzonne D, Monneret C, Arimondo PB, Anklin C, Graves DE, Osheroff N.

Biochemistry. 2011 Jun 7;50(22):5058-66. doi: 10.1021/bi200531q. Epub 2011 May 13.


Interactions between the etoposide derivative F14512 and human type II topoisomerases: implications for the C4 spermine moiety in promoting enzyme-mediated DNA cleavage.

Gentry AC, Pitts SL, Jablonsky MJ, Bailly C, Graves DE, Osheroff N.

Biochemistry. 2011 Apr 19;50(15):3240-9. doi: 10.1021/bi200094z. Epub 2011 Mar 28.


Interactions of actinomycin D with human telomeric G-quadruplex DNA.

Hudson JS, Brooks SC, Graves DE.

Biochemistry. 2009 Jun 2;48(21):4440-7. doi: 10.1021/bi900203z.


Toll-like receptor 9 mediates CpG oligonucleotide-induced cellular invasion.

Ilvesaro JM, Merrell MA, Li L, Wakchoure S, Graves D, Brooks S, Rahko E, Jukkola-Vuorinen A, Vuopala KS, Harris KW, Selander KS.

Mol Cancer Res. 2008 Oct;6(10):1534-43. doi: 10.1158/1541-7786.MCR-07-2005.


Substituents on etoposide that interact with human topoisomerase IIalpha in the binary enzyme-drug complex: contributions to etoposide binding and activity.

Bender RP, Jablonksy MJ, Shadid M, Romaine I, Dunlap N, Anklin C, Graves DE, Osheroff N.

Biochemistry. 2008 Apr 15;47(15):4501-9. doi: 10.1021/bi702019z. Epub 2008 Mar 21.


Antiviral and anticancer optimization studies of the DNA-binding marine natural product aaptamine.

Bowling JJ, Pennaka HK, Ivey K, Wahyuono S, Kelly M, Schinazi RF, Valeriote FA, Graves DE, Hamann MT.

Chem Biol Drug Des. 2008 Mar;71(3):205-15. doi: 10.1111/j.1747-0285.2008.00628.x.


Topoisomerase II - drug interaction domains: identification of substituents on etoposide that interact with the enzyme.

Wilstermann AM, Bender RP, Godfrey M, Choi S, Anklin C, Berkowitz DB, Osheroff N, Graves DE.

Biochemistry. 2007 Jul 17;46(28):8217-25. Epub 2007 Jun 20.


Applications of nanoparticles to diagnostics and therapeutics in colorectal cancer.

Fortina P, Kricka LJ, Graves DJ, Park J, Hyslop T, Tam F, Halas N, Surrey S, Waldman SA.

Trends Biotechnol. 2007 Apr;25(4):145-52. Epub 2007 Feb 21. Review.


Opportunities for near-infrared thermal ablation of colorectal metastases by guanylyl cyclase C-targeted gold nanoshells.

Waldman SA, Fortina P, Surrey S, Hyslop T, Kricka LJ, Graves DJ.

Future Oncol. 2006 Dec;2(6):705-16. Review.


Differential adhesion of microspheres mediated by DNA hybridization I: experiment.

Zhang Y, Milam VT, Graves DJ, Hammer DA.

Biophys J. 2006 Jun 1;90(11):4128-36. Epub 2006 Mar 13.

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