A comparative study on third trimester fetal biometric parameters with maternal age

PeerJ. 2023 Jan 19:11:e14528. doi: 10.7717/peerj.14528. eCollection 2023.

Abstract

Background: Advanced maternal age is an important parameter associated with increased risk of feto-maternal complications and it is an evolving trend in society for women planning for pregnancy in late ages. However there are no studies done whether advanced maternal age has its effects on expression of growth pattern in the fetus. So this study was done to compare the maternal age with the third trimester fetal biometric parameters.

Methods: This study was done in 100 antenatal women and divided into two groups: Group 1: optimal maternal age group between 21-29 years of age and Group 2: advanced maternal age 30 and above. The pre-pregnant maternal weight, gestational age and third trimester fetal biometrics using ultrasound are noted and compared between the groups.

Results: The maternal weight gain between the groups was optimal but the third trimester fetal parameters were significantly less in advanced maternal age. The abdominal circumference in optimal age group and head circumference in advanced maternal age group was closer to calculated estimated date of delivery (EDD) and would be specific in calculating the gestational age.

Conclusions: Though there is no significant difference in maternal weight gain, there are fetal growth restrictions in advanced maternal age group due to which the third trimester fetal parameters are lesser than the optimal age group. Head circumference would be specific in calculating the estimated date of delivery in advanced maternal age group.

Keywords: Biometry; Fetal development; Gestational age; Prenatal ultrasonography; Third trimester.

MeSH terms

  • Adult
  • Biometry
  • Female
  • Fetus / diagnostic imaging
  • Gestational Weight Gain*
  • Humans
  • Maternal Age
  • Pregnancy
  • Pregnancy Trimester, Third
  • Ultrasonography, Prenatal
  • Young Adult

Grants and funding

The authors received no funding for this work.