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Results: 1 to 20 of 21

1.

Discordant results obtained with Francisella tularensis during in vitro and in vivo immunological studies are attributable to compromised bacterial structural integrity.

Singh A, Rahman T, Malik M, Hickey AJ, Leifer CA, Hazlett KR, Sellati TJ.

PLoS One. 2013;8(3):e58513. doi: 10.1371/journal.pone.0058513. Epub 2013 Mar 12.

PMID:
23554897
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Participation of MyD88 and interleukin-33 as innate drivers of Th2 immunity to Trichinella spiralis.

Scalfone LK, Nel HJ, Gagliardo LF, Cameron JL, Al-Shokri S, Leifer CA, Fallon PG, Appleton JA.

Infect Immun. 2013 Apr;81(4):1354-63. doi: 10.1128/IAI.01307-12. Epub 2013 Feb 12.

PMID:
23403558
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Traditional biochemical assays for studying toll-like receptor 9.

Leifer CA, Rose WA 2nd, Botelho F.

J Immunoassay Immunochem. 2013;34(1):1-15. doi: 10.1080/15321819.2012.666222. Review.

PMID:
23323977
[PubMed - indexed for MEDLINE]
4.

Multifunctional role of dextran sulfate sodium for in vivo modeling of intestinal diseases.

Rose WA 2nd, Sakamoto K, Leifer CA.

BMC Immunol. 2012 Aug 1;13:41. doi: 10.1186/1471-2172-13-41.

PMID:
22853702
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Heterozygous carriage of a dysfunctional Toll-like receptor 9 allele affects CpG oligonucleotide responses in B cells.

Knezević J, Pavlinić D, Rose WA 2nd, Leifer CA, Bendelja K, Gabrilovac J, Parcina M, Lauc G, Kubarenko AV, Petricevic B, Vrbanec D, Bulat-Kardum L, Bekeredjian-Ding I, Pavelić J, Dembić Z, Weber AN.

J Biol Chem. 2012 Jul 13;287(29):24544-53. doi: 10.1074/jbc.M111.337477. Epub 2012 May 21.

PMID:
22613717
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Heat shock protein gp96 regulates Toll-like receptor 9 proteolytic processing and conformational stability.

Brooks JC, Sun W, Chiosis G, Leifer CA.

Biochem Biophys Res Commun. 2012 May 18;421(4):780-4. doi: 10.1016/j.bbrc.2012.04.083. Epub 2012 Apr 23.

PMID:
22554506
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Negative regulation of signaling by a soluble form of toll-like receptor 9.

Chockalingam A, Cameron JL, Brooks JC, Leifer CA.

Eur J Immunol. 2011 Aug;41(8):2176-84. doi: 10.1002/eji.201041034. Epub 2011 Jul 4.

PMID:
21604257
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Early response of mucosal epithelial cells during Toxoplasma gondii infection.

Ju CH, Chockalingam A, Leifer CA.

J Immunol. 2009 Dec 1;183(11):7420-7. doi: 10.4049/jimmunol.0900640. Epub 2009 Nov 16.

PMID:
19917706
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis.

Bowdish DM, Sakamoto K, Kim MJ, Kroos M, Mukhopadhyay S, Leifer CA, Tryggvason K, Gordon S, Russell DG.

PLoS Pathog. 2009 Jun;5(6):e1000474. doi: 10.1371/journal.ppat.1000474. Epub 2009 Jun 12.

PMID:
19521507
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA.

Chockalingam A, Brooks JC, Cameron JL, Blum LK, Leifer CA.

Immunol Cell Biol. 2009 Mar-Apr;87(3):209-17. doi: 10.1038/icb.2008.101. Epub 2008 Dec 16.

PMID:
19079358
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Inhibition of TLR3 and TLR4 function and expression in human dendritic cells by helminth parasites.

Semnani RT, Venugopal PG, Leifer CA, Mostböck S, Sabzevari H, Nutman TB.

Blood. 2008 Aug 15;112(4):1290-8. doi: 10.1182/blood-2008-04-149856. Epub 2008 Jun 9.

PMID:
18541719
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Cytoplasmic targeting motifs control localization of toll-like receptor 9.

Leifer CA, Brooks JC, Hoelzer K, Lopez J, Kennedy MN, Mazzoni A, Segal DM.

J Biol Chem. 2006 Nov 17;281(46):35585-92. Epub 2006 Sep 21.

PMID:
16990271
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Dendritic cell modulation by mast cells controls the Th1/Th2 balance in responding T cells.

Mazzoni A, Siraganian RP, Leifer CA, Segal DM.

J Immunol. 2006 Sep 15;177(6):3577-81.

PMID:
16951316
[PubMed - indexed for MEDLINE]
Free Article
14.

TLR9 is localized in the endoplasmic reticulum prior to stimulation.

Leifer CA, Kennedy MN, Mazzoni A, Lee C, Kruhlak MJ, Segal DM.

J Immunol. 2004 Jul 15;173(2):1179-83.

PMID:
15240708
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A complex of soluble MD-2 and lipopolysaccharide serves as an activating ligand for Toll-like receptor 4.

Kennedy MN, Mullen GE, Leifer CA, Lee C, Mazzoni A, Dileepan KN, Segal DM.

J Biol Chem. 2004 Aug 13;279(33):34698-704. Epub 2004 Jun 1.

PMID:
15175334
[PubMed - indexed for MEDLINE]
Free Article
16.

Leucine-rich repeats and pathogen recognition in Toll-like receptors.

Bell JK, Mullen GE, Leifer CA, Mazzoni A, Davies DR, Segal DM.

Trends Immunol. 2003 Oct;24(10):528-33. Review.

PMID:
14552836
[PubMed - indexed for MEDLINE]
17.

Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent.

Huang LY, Aliberti J, Leifer CA, Segal DM, Sher A, Golenbock DT, Golding B.

J Immunol. 2003 Aug 1;171(3):1441-6.

PMID:
12874236
[PubMed - indexed for MEDLINE]
Free Article
18.

Heterogeneity in the human response to immunostimulatory CpG oligodeoxynucleotides.

Leifer CA, Verthelyi D, Klinman DM.

J Immunother. 2003 Jul-Aug;26(4):313-9.

PMID:
12843793
[PubMed - indexed for MEDLINE]
19.

The role of disulfide bonds in the assembly and function of MD-2.

Mullen GE, Kennedy MN, Visintin A, Mazzoni A, Leifer CA, Davies DR, Segal DM.

Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3919-24. Epub 2003 Mar 17.

PMID:
12642668
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Cutting edge: histamine inhibits IFN-alpha release from plasmacytoid dendritic cells.

Mazzoni A, Leifer CA, Mullen GE, Kennedy MN, Klinman DM, Segal DM.

J Immunol. 2003 Mar 1;170(5):2269-73.

PMID:
12594246
[PubMed - indexed for MEDLINE]
Free Article

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