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Items: 1 to 20 of 93

1.

Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation.

He S, Limi S, McGreal RS, Xie Q, Brennan LA, Kantorow WL, Kokavec J, Majumdar R, Hou H Jr, Edelmann W, Liu W, Ashery-Padan R, Zavadil J, Kantorow M, Skoultchi AI, Stopka T, Cvekl A.

Development. 2016 Jun 1;143(11):1937-47. doi: 10.1242/dev.135285.

PMID:
27246713
2.

Intercellular Adhesion-Dependent Cell Survival and ROCK-Regulated Actomyosin-Driven Forces Mediate Self-Formation of a Retinal Organoid.

Lowe A, Harris R, Bhansali P, Cvekl A, Liu W.

Stem Cell Reports. 2016 May 10;6(5):743-56. doi: 10.1016/j.stemcr.2016.03.011. Epub 2016 Apr 28.

3.

PAX6: 25th anniversary and more to learn.

Cvekl A, Callaerts P.

Exp Eye Res. 2016 Apr 25. pii: S0014-4835(16)30090-2. doi: 10.1016/j.exer.2016.04.017. [Epub ahead of print]

PMID:
27126352
4.

Regulation of c-Maf and αA-Crystallin in Ocular Lens by Fibroblast Growth Factor Signaling.

Xie Q, McGreal R, Harris R, Gao CY, Liu W, Reneker LW, Musil LS, Cvekl A.

J Biol Chem. 2016 Feb 19;291(8):3947-58. doi: 10.1074/jbc.M115.705103. Epub 2015 Dec 30.

PMID:
26719333
5.

Unfolded-protein response-associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation, leading to cataract.

Lyu L, Whitcomb EA, Jiang S, Chang ML, Gu Y, Duncan MK, Cvekl A, Wang WL, Limi S, Reneker LW, Shang F, Du L, Taylor A.

FASEB J. 2016 Mar;30(3):1087-95. doi: 10.1096/fj.15-278036. Epub 2015 Nov 20.

PMID:
26590164
6.

Chromatin features, RNA polymerase II and the comparative expression of lens genes encoding crystallins, transcription factors, and autophagy mediators.

Sun J, Rockowitz S, Chauss D, Wang P, Kantorow M, Zheng D, Cvekl A.

Mol Vis. 2015 Aug 28;21:955-73. eCollection 2015.

7.

Lens Biology and Biochemistry.

Hejtmancik JF, Riazuddin SA, McGreal R, Liu W, Cvekl A, Shiels A.

Prog Mol Biol Transl Sci. 2015;134:169-201. doi: 10.1016/bs.pmbts.2015.04.007. Epub 2015 Jun 4. Review.

PMID:
26310155
8.

Lens Development and Crystallin Gene Expression.

Cvekl A, McGreal R, Liu W.

Prog Mol Biol Transl Sci. 2015;134:129-67. doi: 10.1016/bs.pmbts.2015.05.001. Epub 2015 Jun 12. Review.

PMID:
26310154
9.

Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development.

Sun J, Rockowitz S, Xie Q, Ashery-Padan R, Zheng D, Cvekl A.

Nucleic Acids Res. 2015 Aug 18;43(14):6827-46. doi: 10.1093/nar/gkv589. Epub 2015 Jul 2.

10.

The cellular and molecular mechanisms of vertebrate lens development.

Cvekl A, Ashery-Padan R.

Development. 2014 Dec;141(23):4432-47. doi: 10.1242/dev.107953. Epub 2014 Nov 18. Review.

11.

Mammalian TBX1 preferentially binds and regulates downstream targets via a tandem T-site repeat.

Castellanos R, Xie Q, Zheng D, Cvekl A, Morrow BE.

PLoS One. 2014 May 5;9(5):e95151. doi: 10.1371/journal.pone.0095151. eCollection 2014.

12.

Gene regulation by PAX6: structural-functional correlations of missense mutants and transcriptional control of Trpm3/miR-204.

Xie Q, Ung D, Khafizov K, Fiser A, Cvekl A.

Mol Vis. 2014 Mar 6;20:270-82. eCollection 2014.

13.

Identification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiation.

Wolf L, Gao CS, Gueta K, Xie Q, Chevallier T, Podduturi NR, Sun J, Conte I, Zelenka PS, Ashery-Padan R, Zavadil J, Cvekl A.

G3 (Bethesda). 2013 Dec 9;3(12):2239-55. doi: 10.1534/g3.113.008698.

14.

Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.

Wolf L, Harrison W, Huang J, Xie Q, Xiao N, Sun J, Kong L, Lachke SA, Kuracha MR, Govindarajan V, Brindle PK, Ashery-Padan R, Beebe DC, Overbeek PA, Cvekl A.

Nucleic Acids Res. 2013 Dec;41(22):10199-214. doi: 10.1093/nar/gkt824. Epub 2013 Sep 12.

15.

Pax6 regulates gene expression in the vertebrate lens through miR-204.

Shaham O, Gueta K, Mor E, Oren-Giladi P, Grinberg D, Xie Q, Cvekl A, Shomron N, Davis N, Keydar-Prizant M, Raviv S, Pasmanik-Chor M, Bell RE, Levy C, Avellino R, Banfi S, Conte I, Ashery-Padan R.

PLoS Genet. 2013;9(3):e1003357. doi: 10.1371/journal.pgen.1003357. Epub 2013 Mar 14.

16.

Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation.

Walcher T, Xie Q, Sun J, Irmler M, Beckers J, Öztürk T, Niessing D, Stoykova A, Cvekl A, Ninkovic J, Götz M.

Development. 2013 Mar;140(5):1123-36. doi: 10.1242/dev.082875.

17.

Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain.

Xie Q, Yang Y, Huang J, Ninkovic J, Walcher T, Wolf L, Vitenzon A, Zheng D, Götz M, Beebe DC, Zavadil J, Cvekl A.

PLoS One. 2013;8(1):e54507. doi: 10.1371/journal.pone.0054507. Epub 2013 Jan 14.

18.

Constitutive overexpression of Norrin activates Wnt/β-catenin and endothelin-2 signaling to protect photoreceptors from light damage.

Braunger BM, Ohlmann A, Koch M, Tanimoto N, Volz C, Yang Y, Bösl MR, Cvekl A, Jägle H, Seeliger MW, Tamm ER.

Neurobiol Dis. 2013 Feb;50:1-12. doi: 10.1016/j.nbd.2012.09.008. Epub 2012 Sep 23.

PMID:
23009755
19.

Spatial expression patterns of autophagy genes in the eye lens and induction of autophagy in lens cells.

Brennan LA, Kantorow WL, Chauss D, McGreal R, He S, Mattucci L, Wei J, Riazuddin SA, Cvekl A, Hejtmancik JF, Kantorow M.

Mol Vis. 2012;18:1773-86. Epub 2012 Jun 30.

20.

The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops.

Xie Q, Cvekl A.

J Biol Chem. 2011 Dec 16;286(50):43259-71. doi: 10.1074/jbc.M111.264580. Epub 2011 Oct 13.

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