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Results: 13

1.

Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma.

Lim WK, Ong CK, Tan J, Thike AA, Ng CC, Rajasegaran V, Myint SS, Nagarajan S, Nasir ND, McPherson JR, Cutcutache I, Poore G, Tay ST, Ooi WS, Tan VK, Hartman M, Ong KW, Tan BK, Rozen SG, Tan PH, Tan P, Teh BT.

Nat Genet. 2014 Aug;46(8):877-80. doi: 10.1038/ng.3037. Epub 2014 Jul 20.

PMID:
25038752
[PubMed - in process]
2.

Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers.

Chan-On W, Nairismägi ML, Ong CK, Lim WK, Dima S, Pairojkul C, Lim KH, McPherson JR, Cutcutache I, Heng HL, Ooi L, Chung A, Chow P, Cheow PC, Lee SY, Choo SP, Tan IB, Duda D, Nastase A, Myint SS, Wong BH, Gan A, Rajasegaran V, Ng CC, Nagarajan S, Jusakul A, Zhang S, Vohra P, Yu W, Huang D, Sithithaworn P, Yongvanit P, Wongkham S, Khuntikeo N, Bhudhisawasdi V, Popescu I, Rozen SG, Tan P, Teh BT.

Nat Genet. 2013 Dec;45(12):1474-8. doi: 10.1038/ng.2806. Epub 2013 Nov 3.

PMID:
24185513
[PubMed - indexed for MEDLINE]
3.

Genome-wide mutational signatures of aristolochic acid and its application as a screening tool.

Poon SL, Pang ST, McPherson JR, Yu W, Huang KK, Guan P, Weng WH, Siew EY, Liu Y, Heng HL, Chong SC, Gan A, Tay ST, Lim WK, Cutcutache I, Huang D, Ler LD, Nairismägi ML, Lee MH, Chang YH, Yu KJ, Chan-On W, Li BK, Yuan YF, Qian CN, Ng KF, Wu CF, Hsu CL, Bunte RM, Stratton MR, Futreal PA, Sung WK, Chuang CK, Ong CK, Rozen SG, Tan P, Teh BT.

Sci Transl Med. 2013 Aug 7;5(197):197ra101. doi: 10.1126/scitranslmed.3006086.

PMID:
23926199
[PubMed - indexed for MEDLINE]
Free Article
4.

Whole-genome reconstruction and mutational signatures in gastric cancer.

Nagarajan N, Bertrand D, Hillmer AM, Zang ZJ, Yao F, Jacques PÉ, Teo AS, Cutcutache I, Zhang Z, Lee WH, Sia YY, Gao S, Ariyaratne PN, Ho A, Woo XY, Veeravali L, Ong CK, Deng N, Desai KV, Khor CC, Hibberd ML, Shahab A, Rao J, Wu M, Teh M, Zhu F, Chin SY, Pang B, So JB, Bourque G, Soong R, Sung WK, Tean Teh B, Rozen S, Ruan X, Yeoh KG, Tan PB, Ruan Y.

Genome Biol. 2012 Dec 13;13(12):R115. doi: 10.1186/gb-2012-13-12-r115.

PMID:
23237666
[PubMed - in process]
Free PMC Article
5.

Primer3--new capabilities and interfaces.

Untergasser A, Cutcutache I, Koressaar T, Ye J, Faircloth BC, Remm M, Rozen SG.

Nucleic Acids Res. 2012 Aug;40(15):e115. Epub 2012 Jun 22.

PMID:
22730293
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction.

Ye J, Coulouris G, Zaretskaya I, Cutcutache I, Rozen S, Madden TL.

BMC Bioinformatics. 2012 Jun 18;13:134. doi: 10.1186/1471-2105-13-134.

PMID:
22708584
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Janus kinase 3-activating mutations identified in natural killer/T-cell lymphoma.

Koo GC, Tan SY, Tang T, Poon SL, Allen GE, Tan L, Chong SC, Ong WS, Tay K, Tao M, Quek R, Loong S, Yeoh KW, Yap SP, Lee KA, Lim LC, Tan D, Goh C, Cutcutache I, Yu W, Ng CC, Rajasegaran V, Heng HL, Gan A, Ong CK, Rozen S, Tan P, Teh BT, Lim ST.

Cancer Discov. 2012 Jul;2(7):591-7. doi: 10.1158/2159-8290.CD-12-0028. Epub 2012 Jun 15.

PMID:
22705984
[PubMed - indexed for MEDLINE]
8.

Exome sequencing of liver fluke-associated cholangiocarcinoma.

Ong CK, Subimerb C, Pairojkul C, Wongkham S, Cutcutache I, Yu W, McPherson JR, Allen GE, Ng CC, Wong BH, Myint SS, Rajasegaran V, Heng HL, Gan A, Zang ZJ, Wu Y, Wu J, Lee MH, Huang D, Ong P, Chan-on W, Cao Y, Qian CN, Lim KH, Ooi A, Dykema K, Furge K, Kukongviriyapan V, Sripa B, Wongkham C, Yongvanit P, Futreal PA, Bhudhisawasdi V, Rozen S, Tan P, Teh BT.

Nat Genet. 2012 May 6;44(6):690-3. doi: 10.1038/ng.2273.

PMID:
22561520
[PubMed - indexed for MEDLINE]
9.

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes.

Zang ZJ, Cutcutache I, Poon SL, Zhang SL, McPherson JR, Tao J, Rajasegaran V, Heng HL, Deng N, Gan A, Lim KH, Ong CK, Huang D, Chin SY, Tan IB, Ng CC, Yu W, Wu Y, Lee M, Wu J, Poh D, Wan WK, Rha SY, So J, Salto-Tellez M, Yeoh KG, Wong WK, Zhu YJ, Futreal PA, Pang B, Ruan Y, Hillmer AM, Bertrand D, Nagarajan N, Rozen S, Teh BT, Tan P.

Nat Genet. 2012 May;44(5):570-4. doi: 10.1038/ng.2246.

PMID:
22484628
[PubMed - indexed for MEDLINE]
10.

First somatic mutation of E2F1 in a critical DNA binding residue discovered in well-differentiated papillary mesothelioma of the peritoneum.

Yu W, Chan-On W, Teo M, Ong CK, Cutcutache I, Allen GE, Wong B, Myint SS, Lim KH, Voorhoeve PM, Rozen S, Soo KC, Tan P, Teh BT.

Genome Biol. 2011 Sep 28;12(9):R96. doi: 10.1186/gb-2011-12-9-r96.

PMID:
21955916
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Fanconi's anemia in adulthood: chemoradiation-induced bone marrow failure and a novel FANCA mutation identified by targeted deep sequencing.

Tan IB, Cutcutache I, Zang ZJ, Iqbal J, Yap SF, Hwang W, Lim WT, Teh BT, Rozen S, Tan EH, Tan P.

J Clin Oncol. 2011 Jul 10;29(20):e591-4. doi: 10.1200/JCO.2011.35.1064. Epub 2011 Apr 25. No abstract available.

PMID:
21519011
[PubMed - indexed for MEDLINE]
Free Article
12.

Assessing matched normal and tumor pairs in next-generation sequencing studies.

Goh L, Chen GB, Cutcutache I, Low B, Teh BT, Rozen S, Tan P.

PLoS One. 2011 Mar 18;6(3):e17810. doi: 10.1371/journal.pone.0017810.

PMID:
21445261
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencing.

Zang ZJ, Ong CK, Cutcutache I, Yu W, Zhang SL, Huang D, Ler LD, Dykema K, Gan A, Tao J, Lim S, Liu Y, Futreal PA, Grabsch H, Furge KA, Goh LK, Rozen S, Teh BT, Tan P.

Cancer Res. 2011 Jan 1;71(1):29-39. doi: 10.1158/0008-5472.CAN-10-1749. Epub 2010 Nov 19.

PMID:
21097718
[PubMed - indexed for MEDLINE]
Free PMC Article

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