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Results: 1 to 20 of 30

1.

Phase I Dose Escalation Study of MEDI-573, a Bispecific, Anti-ligand Monoclonal Antibody against IGF-I and IGF-II, in Patients with Advanced Solid Tumors.

Haluska P, Menefee ME, Plimack ER, Rosenberg JE, Northfelt DW, LaVallee T, Shi L, Yu XQ, Burke PA, Huang J, Viner J, McDevitt J, LoRusso PM.

Clin Cancer Res. 2014 Jul 14. pii: clincanres.0114.2014. [Epub ahead of print]

PMID:
25024259
[PubMed - as supplied by publisher]
2.

Potential advantages of CUDC-101, a multitargeted HDAC, EGFR, and HER2 inhibitor, in treating drug resistance and preventing cancer cell migration and invasion.

Wang J, Pursell NW, Samson ME, Atoyan R, Ma AW, Selmi A, Xu W, Cai X, Voi M, Savagner P, Lai CJ.

Mol Cancer Ther. 2013 Jun;12(6):925-36. doi: 10.1158/1535-7163.MCT-12-1045. Epub 2013 Mar 27.

PMID:
23536719
[PubMed - indexed for MEDLINE]
Free Article
3.

Cancer network disruption by a single molecule inhibitor targeting both histone deacetylase activity and phosphatidylinositol 3-kinase signaling.

Qian C, Lai CJ, Bao R, Wang DG, Wang J, Xu GX, Atoyan R, Qu H, Yin L, Samson M, Zifcak B, Ma AW, DellaRocca S, Borek M, Zhai HX, Cai X, Voi M.

Clin Cancer Res. 2012 Aug 1;18(15):4104-13. doi: 10.1158/1078-0432.CCR-12-0055. Epub 2012 Jun 12.

PMID:
22693356
[PubMed - indexed for MEDLINE]
Free Article
4.

Statistical methodology for the detection of small changes in distances by EXAFS: application to the antimalarial ruthenoquine.

Curis E, Dubar F, Nicolis I, Bénazeth S, Biot C.

J Phys Chem A. 2012 Jun 14;116(23):5577-85. doi: 10.1021/jp301811r. Epub 2012 May 31.

PMID:
22607521
[PubMed - indexed for MEDLINE]
5.

CUDC-101, a multitargeted inhibitor of histone deacetylase, epidermal growth factor receptor, and human epidermal growth factor receptor 2, exerts potent anticancer activity.

Lai CJ, Bao R, Tao X, Wang J, Atoyan R, Qu H, Wang DG, Yin L, Samson M, Forrester J, Zifcak B, Xu GX, DellaRocca S, Zhai HX, Cai X, Munger WE, Keegan M, Pepicelli CV, Qian C.

Cancer Res. 2010 May 1;70(9):3647-56. doi: 10.1158/0008-5472.CAN-09-3360. Epub 2010 Apr 13.

PMID:
20388807
[PubMed - indexed for MEDLINE]
Free Article
6.

Discovery of 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide (CUDc-101) as a potent multi-acting HDAC, EGFR, and HER2 inhibitor for the treatment of cancer.

Cai X, Zhai HX, Wang J, Forrester J, Qu H, Yin L, Lai CJ, Bao R, Qian C.

J Med Chem. 2010 Mar 11;53(5):2000-9. doi: 10.1021/jm901453q.

PMID:
20143778
[PubMed - indexed for MEDLINE]
7.

Targeting heat shock protein 90 with CUDC-305 overcomes erlotinib resistance in non-small cell lung cancer.

Bao R, Lai CJ, Wang DG, Qu H, Yin L, Zifcak B, Tao X, Wang J, Atoyan R, Samson M, Forrester J, Xu GX, DellaRocca S, Borek M, Zhai HX, Cai X, Qian C.

Mol Cancer Ther. 2009 Dec;8(12):3296-306. doi: 10.1158/1535-7163.MCT-09-0538. Epub .

PMID:
19952121
[PubMed - indexed for MEDLINE]
Free Article
8.

Mathematical modeling in metal metabolism: overview and perspectives.

Curis E, Nicolis I, Bensaci J, Deschamps P, Bénazeth S.

Biochimie. 2009 Oct;91(10):1238-54. doi: 10.1016/j.biochi.2009.06.019. Epub 2009 Jul 9. Review.

PMID:
19596399
[PubMed - indexed for MEDLINE]
9.

CUDC-305, a novel synthetic HSP90 inhibitor with unique pharmacologic properties for cancer therapy.

Bao R, Lai CJ, Qu H, Wang D, Yin L, Zifcak B, Atoyan R, Wang J, Samson M, Forrester J, DellaRocca S, Xu GX, Tao X, Zhai HX, Cai X, Qian C.

Clin Cancer Res. 2009 Jun 15;15(12):4046-57. doi: 10.1158/1078-0432.CCR-09-0152. Epub 2009 Jun 9.

PMID:
19509149
[PubMed - indexed for MEDLINE]
Free Article
10.

NAD and axon degeneration: from the Wlds gene to neurochemistry.

Wang J, He Z.

Cell Adh Migr. 2009 Jan-Mar;3(1):77-87. Epub 2009 Jan 25. Review.

PMID:
19372760
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Citrulline and the gut.

Curis E, Crenn P, Cynober L.

Curr Opin Clin Nutr Metab Care. 2007 Sep;10(5):620-6. Review.

PMID:
17693747
[PubMed - indexed for MEDLINE]
12.

Lactosamine modulates the rate of migration of GnRH neurons during mouse development.

Bless E, Raitcheva D, Henion TR, Tobet S, Schwarting GA.

Eur J Neurosci. 2006 Aug;24(3):654-60.

PMID:
16930397
[PubMed - indexed for MEDLINE]
13.

The hedgehog pathway and neurological disorders.

Dellovade T, Romer JT, Curran T, Rubin LL.

Annu Rev Neurosci. 2006;29:539-63. Review.

PMID:
16776596
[PubMed - indexed for MEDLINE]
14.

Propagation of statistical errors across EXAFS extraction and Fourier filtering.

Curis E, Bénazeth S.

J Synchrotron Radiat. 2000 Jul 1;7(Pt 4):262-6. Epub 2000 Jul 1.

PMID:
16609205
[PubMed]
15.

Modulation of hair growth with small molecule agonists of the hedgehog signaling pathway.

Paladini RD, Saleh J, Qian C, Xu GX, Rubin LL.

J Invest Dermatol. 2005 Oct;125(4):638-46.

PMID:
16185261
[PubMed - indexed for MEDLINE]
Free Article
16.

Almost all about citrulline in mammals.

Curis E, Nicolis I, Moinard C, Osowska S, Zerrouk N, Bénazeth S, Cynober L.

Amino Acids. 2005 Nov;29(3):177-205. Epub 2005 Aug 8. Review.

PMID:
16082501
[PubMed - indexed for MEDLINE]
17.

About estimation of fitted parameters' statistical uncertainties in EXAFS. Critical approach on usual and Monte Carlo methods.

Curis E, Bénazeth S.

J Synchrotron Radiat. 2005 May;12(Pt 3):361-73. Epub 2005 Apr 14.

PMID:
15840923
[PubMed]
18.

A non-peptidyl neurotrophic small molecule for midbrain dopaminergic neurons.

Lin LF, Rubin LL, Xu M.

J Neurochem. 2004 Jun;89(6):1387-95.

PMID:
15189341
[PubMed - indexed for MEDLINE]
19.

Estrogen regulation of neurokinin B gene expression in the mouse arcuate nucleus is mediated by estrogen receptor alpha.

Dellovade TL, Merchenthaler I.

Endocrinology. 2004 Feb;145(2):736-42. Epub 2003 Oct 30.

PMID:
14592957
[PubMed - indexed for MEDLINE]
20.

Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions.

Williams JA, Guicherit OM, Zaharian BI, Xu Y, Chai L, Wichterle H, Kon C, Gatchalian C, Porter JA, Rubin LL, Wang FY.

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4616-21. Epub 2003 Apr 4. Erratum in: Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8607.

PMID:
12679522
[PubMed - indexed for MEDLINE]
Free PMC Article

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