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Results: 1 to 20 of 243

1.

Clinical delineation and natural history of the PIK3CA-related overgrowth spectrum.

Keppler-Noreuil KM, Sapp JC, Lindhurst MJ, Parker VE, Blumhorst C, Darling T, Tosi LL, Huson SM, Whitehouse RW, Jakkula E, Grant I, Balasubramanian M, Chandler KE, Fraser JL, Gucev Z, Crow YJ, Brennan LM, Clark R, Sellars EA, Pena LD, Krishnamurty V, Shuen A, Braverman N, Cunningham ML, Sutton VR, Tasic V, Graham JM Jr, Geer J Jr, Henderson A, Semple RK, Biesecker LG.

Am J Med Genet A. 2014 Jul;164(7):1713-33. doi: 10.1002/ajmg.a.36552. Epub 2014 Apr 29.

PMID:
24782230
[PubMed - in process]
2.

Anthracimycin activity against contemporary methicillin-resistant Staphylococcus aureus.

Hensler ME, Jang KH, Thienphrapa W, Vuong L, Tran DN, Soubih E, Lin L, Haste NM, Cunningham ML, Kwan BP, Shaw KJ, Fenical W, Nizet V.

J Antibiot (Tokyo). 2014 Apr 16. doi: 10.1038/ja.2014.36. [Epub ahead of print]

PMID:
24736856
[PubMed - as supplied by publisher]
3.

Clinical evidence for a mandibular to maxillary transformation in Auriculocondylar syndrome.

Gordon CT, Cunniff CM, Green GE, Zechi-Ceide RM, Johnson JM, Henderson A, Petit F, Kokitsu-Nakata NM, Guion-Almeida ML, Munnich A, Cunningham ML, Lyonnet S, Amiel J.

Am J Med Genet A. 2014 Jul;164(7):1850-3. doi: 10.1002/ajmg.a.36505. Epub 2014 Mar 26. No abstract available.

PMID:
24677549
[PubMed - in process]
4.

Structure-based design of new dihydrofolate reductase antibacterial agents: 7-(benzimidazol-1-yl)-2,4-diaminoquinazolines.

Lam T, Hilgers MT, Cunningham ML, Kwan BP, Nelson KJ, Brown-Driver V, Ong V, Trzoss M, Hough G, Shaw KJ, Finn J.

J Med Chem. 2014 Feb 13;57(3):651-68. doi: 10.1021/jm401204g. Epub 2014 Jan 16.

PMID:
24428639
[PubMed - indexed for MEDLINE]
5.

Tricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agents.

Tari LW, Li X, Trzoss M, Bensen DC, Chen Z, Lam T, Zhang J, Lee SJ, Hough G, Phillipson D, Akers-Rodriguez S, Cunningham ML, Kwan BP, Nelson KJ, Castellano A, Locke JB, Brown-Driver V, Murphy TM, Ong VS, Pillar CM, Shinabarger DL, Nix J, Lightstone FC, Wong SE, Nguyen TB, Shaw KJ, Finn J.

PLoS One. 2013 Dec 26;8(12):e84409. doi: 10.1371/journal.pone.0084409. eCollection 2013.

PMID:
24386374
[PubMed - in process]
Free PMC Article
6.

Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.

Corton JC, Cunningham ML, Hummer BT, Lau C, Meek B, Peters JM, Popp JA, Rhomberg L, Seed J, Klaunig JE.

Crit Rev Toxicol. 2014 Jan;44(1):1-49. doi: 10.3109/10408444.2013.835784. Epub 2013 Nov 4.

PMID:
24180432
[PubMed - in process]
7.

Survey of faculty perceptions regarding a peer review system.

Eisenberg RL, Cunningham ML, Siewert B, Kruskal JB.

J Am Coll Radiol. 2014 Apr;11(4):397-401. doi: 10.1016/j.jacr.2013.08.011. Epub 2013 Oct 19.

PMID:
24144835
[PubMed - in process]
8.

Perspectives and challenges in advancing research into craniofacial anomalies.

Cox TC, Luquetti DV, Cunningham ML.

Am J Med Genet C Semin Med Genet. 2013 Nov;163C(4):213-7. doi: 10.1002/ajmg.c.31383. Epub 2013 Oct 18.

PMID:
24142870
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Further characterization of atypical features in auriculocondylar syndrome caused by recessive PLCB4 mutations.

Kido Y, Gordon CT, Sakazume S, Ben Bdira E, Dattani M, Wilson LC, Lyonnet S, Murakami N, Cunningham ML, Amiel J, Nagai T.

Am J Med Genet A. 2013 Sep;161(9):2339-46. doi: 10.1002/ajmg.a.36066. Epub 2013 Aug 2.

PMID:
23913798
[PubMed - indexed for MEDLINE]
10.

Distinguishing on-target versus off-target activity in early antibacterial drug discovery using a macromolecular synthesis assay.

Cunningham ML, Kwan BP, Nelson KJ, Bensen DC, Shaw KJ.

J Biomol Screen. 2013 Oct;18(9):1018-26. doi: 10.1177/1087057113487208. Epub 2013 May 17.

PMID:
23686103
[PubMed - indexed for MEDLINE]
11.

Oculoauriculofrontonasal syndrome: case series revealing new bony nasal anomalies in an old syndrome.

Evans KN, Gruss JS, Khanna PC, Cunningham ML, Cox TC, Hing AV.

Am J Med Genet A. 2013 Jun;161A(6):1345-53. doi: 10.1002/ajmg.a.35926. Epub 2013 May 1.

PMID:
23637006
[PubMed - in process]
12.

MAPK/ERK Signaling Pathway Analysis in Primary Osteoblasts From Patients With Nonsyndromic Sagittal Craniosynostosis.

Kim SD, Yagnik G, Cunningham ML, Kim J, Boyadjiev SA.

Cleft Palate Craniofac J. 2014 Jan;51(1):115-9. doi: 10.1597/12-136. Epub 2013 Apr 8.

PMID:
23566293
[PubMed - in process]
Free PMC Article
13.

Preferential associated anomalies in 818 cases of microtia in South America.

Luquetti DV, Cox TC, Lopez-Camelo J, Dutra Mda G, Cunningham ML, Castilla EE.

Am J Med Genet A. 2013 May;161A(5):1051-7. doi: 10.1002/ajmg.a.35888. Epub 2013 Mar 29.

PMID:
23554119
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.

Teng M, Hilgers MT, Cunningham ML, Borchardt A, Locke JB, Abraham S, Haley G, Kwan BP, Hall C, Hough GW, Shaw KJ, Finn J.

J Med Chem. 2013 Feb 28;56(4):1748-60. doi: 10.1021/jm301756m. Epub 2013 Feb 12.

PMID:
23362938
[PubMed - indexed for MEDLINE]
15.

Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.

Tari LW, Trzoss M, Bensen DC, Li X, Chen Z, Lam T, Zhang J, Creighton CJ, Cunningham ML, Kwan B, Stidham M, Shaw KJ, Lightstone FC, Wong SE, Nguyen TB, Nix J, Finn J.

Bioorg Med Chem Lett. 2013 Mar 1;23(5):1529-36. doi: 10.1016/j.bmcl.2012.11.032. Epub 2012 Dec 5.

PMID:
23352267
[PubMed - indexed for MEDLINE]
16.

Heterogeneity of mutational mechanisms and modes of inheritance in auriculocondylar syndrome.

Gordon CT, Vuillot A, Marlin S, Gerkes E, Henderson A, AlKindy A, Holder-Espinasse M, Park SS, Omarjee A, Sanchis-Borja M, Bdira EB, Oufadem M, Sikkema-Raddatz B, Stewart A, Palmer R, McGowan R, Petit F, Delobel B, Speicher MR, Aurora P, Kilner D, Pellerin P, Simon M, Bonnefont JP, Tobias ES, García-Miñaúr S, Bitner-Glindzicz M, Lindholm P, Meijer BA, Abadie V, Denoyelle F, Vazquez MP, Rotky-Fast C, Couloigner V, Pierrot S, Manach Y, Breton S, Hendriks YM, Munnich A, Jakobsen L, Kroisel P, Lin A, Kaban LB, Basel-Vanagaite L, Wilson L, Cunningham ML, Lyonnet S, Amiel J.

J Med Genet. 2013 Mar;50(3):174-86. doi: 10.1136/jmedgenet-2012-101331. Epub 2013 Jan 12.

PMID:
23315542
[PubMed - indexed for MEDLINE]
17.

Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: development of inhibitors with broad spectrum, Gram-negative antibacterial activity.

Trzoss M, Bensen DC, Li X, Chen Z, Lam T, Zhang J, Creighton CJ, Cunningham ML, Kwan B, Stidham M, Nelson K, Brown-Driver V, Castellano A, Shaw KJ, Lightstone FC, Wong SE, Nguyen TB, Finn J, Tari LW.

Bioorg Med Chem Lett. 2013 Mar 1;23(5):1537-43. doi: 10.1016/j.bmcl.2012.11.073. Epub 2012 Dec 8.

PMID:
23294697
[PubMed - indexed for MEDLINE]
18.

Directed differentiation of human pluripotent cells to neural crest stem cells.

Menendez L, Kulik MJ, Page AT, Park SS, Lauderdale JD, Cunningham ML, Dalton S.

Nat Protoc. 2013 Jan;8(1):203-12. doi: 10.1038/nprot.2012.156. Epub 2013 Jan 3.

PMID:
23288320
[PubMed - indexed for MEDLINE]
19.

Development at age 36 months in children with deformational plagiocephaly.

Collett BR, Gray KE, Starr JR, Heike CL, Cunningham ML, Speltz ML.

Pediatrics. 2013 Jan;131(1):e109-15. doi: 10.1542/peds.2012-1779. Epub 2012 Dec 24.

PMID:
23266929
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

"Mandibulofacial dysostosis with microcephaly" caused by EFTUD2 mutations: expanding the phenotype.

Luquetti DV, Hing AV, Rieder MJ, Nickerson DA, Turner EH, Smith J, Park S, Cunningham ML.

Am J Med Genet A. 2013 Jan;161A(1):108-13. doi: 10.1002/ajmg.a.35696. Epub 2012 Dec 14.

PMID:
23239648
[PubMed - indexed for MEDLINE]
Free PMC Article

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