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Assessment of the Stability of Supraphysiological Ascorbate in Human Blood: Appropriate Handling of Samples from Clinical Trials for Measurements of Pharmacological Ascorbate.
Petronek MS, Wagner BA, Hollenbeck NJ, Caster JM, Spitz DR, Cullen JJ, Buettner GR, Allen BG. Petronek MS, et al. Radiat Res. 2019 Jun;191(6):491-496. doi: 10.1667/RR15328.1. Epub 2019 Apr 30. Radiat Res. 2019. PMID: 31039080 Free PMC article.
After 24 h, ascorbate levels in plasma are relatively stable at 4C for up to 72 h. At -20C, plasma concentrations are relatively stable for 2-3 weeks, while at -80C, ascorbate concentrations in plasma are stable for at least one month. ...Additionally, patient samples can …
After 24 h, ascorbate levels in plasma are relatively stable at 4C for up to 72 h. At -20C, plasma concentrations are relatively stab …