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Results: 1 to 20 of 136

1.

Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.

Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Adam A, Torres D, Zhang X, Dobrolecki LE, Wei W, Lewis MT, Dave B, Chang JC, Landis MD, Creighton CJ, Mancini MA, Tweardy DJ.

Oncogene. 2014 Mar 31;0. doi: 10.1038/onc.2014.72. [Epub ahead of print]

PMID:
24681959
[PubMed - as supplied by publisher]
2.

Plk2 regulates mitotic spindle orientation and mammary gland development.

Villegas E, Kabotyanski EB, Shore AN, Creighton CJ, Westbrook TF, Rosen JM.

Development. 2014 Apr;141(7):1562-71. doi: 10.1242/dev.108258. Epub 2014 Mar 5.

PMID:
24598160
[PubMed - in process]
3.

A murine uterine transcriptome, responsive to steroid receptor coactivator-2, reveals transcription factor 23 as essential for decidualization of human endometrial stromal cells.

Kommagani R, Szwarc MM, Kovanci E, Creighton CJ, O'Malley BW, Demayo FJ, Lydon JP.

Biol Reprod. 2014 Apr 10;90(4):75. doi: 10.1095/biolreprod.114.117531. Print 2014.

PMID:
24571987
[PubMed - in process]
4.

PKA turnover by the REGγ-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis.

Liu S, Lai L, Zuo Q, Dai F, Wu L, Wang Y, Zhou Q, Liu J, Liu J, Li L, Lin Q, Creighton CJ, Costello MG, Huang S, Jia C, Liao L, Luo H, Fu J, Liu M, Yi Z, Xiao J, Li X.

J Mol Cell Cardiol. 2014 Feb 20;72C:28-38. doi: 10.1016/j.yjmcc.2014.02.007. [Epub ahead of print]

PMID:
24560667
[PubMed - as supplied by publisher]
5.

Comprehensive molecular characterization of urothelial bladder carcinoma.

Cancer Genome Atlas Research Network.

Nature. 2014 Mar 20;507(7492):315-22. doi: 10.1038/nature12965. Epub 2014 Jan 29.

PMID:
24476821
[PubMed - indexed for MEDLINE]
6.

The Mef2 transcription network is disrupted in myotonic dystrophy heart tissue, dramatically altering miRNA and mRNA expression.

Kalsotra A, Singh RK, Gurha P, Ward AJ, Creighton CJ, Cooper TA.

Cell Rep. 2014 Jan 30;6(2):336-45. doi: 10.1016/j.celrep.2013.12.025. Epub 2014 Jan 9.

PMID:
24412363
[PubMed - in process]
7.

Widespread molecular patterns associated with drug sensitivity in breast cancer cell lines, with implications for human tumors.

Creighton CJ.

PLoS One. 2013 Dec 27;8(12):e71158. doi: 10.1371/journal.pone.0071158. eCollection 2013.

PMID:
24386073
[PubMed - in process]
Free PMC Article
8.

Effects of TP53 mutational status on gene expression patterns across 10 human cancer types.

Parikh N, Hilsenbeck S, Creighton CJ, Dayaram T, Shuck R, Shinbrot E, Xi L, Gibbs RA, Wheeler DA, Donehower LA.

J Pathol. 2014 Apr;232(5):522-33. doi: 10.1002/path.4321. Epub 2014 Jan 29.

PMID:
24374933
[PubMed - in process]
9.

T lymphocytes redirected against the chondroitin sulfate proteoglycan-4 control the growth of multiple solid tumors both in vitro and in vivo.

Geldres C, Savoldo B, Hoyos V, Caruana I, Zhang M, Yvon E, Del Vecchio M, Creighton CJ, Ittmann M, Ferrone S, Dotti G.

Clin Cancer Res. 2014 Feb 15;20(4):962-71. doi: 10.1158/1078-0432.CCR-13-2218. Epub 2013 Dec 13.

PMID:
24334762
[PubMed - in process]
10.

FGFR1-WNT-TGF-β signaling in prostate cancer mouse models recapitulates human reactive stroma.

Carstens JL, Shahi P, Van Tsang S, Smith B, Creighton CJ, Zhang Y, Seamans A, Seethammagari M, Vedula I, Levitt JM, Ittmann MM, Rowley DR, Spencer DM.

Cancer Res. 2014 Jan 15;74(2):609-20. doi: 10.1158/0008-5472.CAN-13-1093. Epub 2013 Dec 4.

PMID:
24305876
[PubMed - indexed for MEDLINE]
11.

Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans.

Clementi C, Tripurani SK, Large MJ, Edson MA, Creighton CJ, Hawkins SM, Kovanci E, Kaartinen V, Lydon JP, Pangas SA, DeMayo FJ, Matzuk MM.

PLoS Genet. 2013 Nov;9(11):e1003863. doi: 10.1371/journal.pgen.1003863. Epub 2013 Nov 14.

PMID:
24244176
[PubMed - in process]
Free PMC Article
12.

Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization.

Kommagani R, Szwarc MM, Kovanci E, Gibbons WE, Putluri N, Maity S, Creighton CJ, Sreekumar A, DeMayo FJ, Lydon JP, O'Malley BW.

PLoS Genet. 2013 Oct;9(10):e1003900. doi: 10.1371/journal.pgen.1003900. Epub 2013 Oct 24.

PMID:
24204309
[PubMed - in process]
Free PMC Article
13.

COUP-TFII regulates human endometrial stromal genes involved in inflammation.

Li X, Large MJ, Creighton CJ, Lanz RB, Jeong JW, Young SL, Lessey BA, Palomino WA, Tsai SY, Demayo FJ.

Mol Endocrinol. 2013 Dec;27(12):2041-54. doi: 10.1210/me.2013-1191. Epub 2013 Oct 31.

PMID:
24176914
[PubMed - in process]
14.

EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis.

Zhang P, Garnett J, Creighton CJ, Al Sannaa GA, Igram DR, Lazar A, Liu X, Liu C, Pollock RE.

J Pathol. 2014 Feb;232(3):308-18. doi: 10.1002/path.4294.

PMID:
24132643
[PubMed - indexed for MEDLINE]
15.

Amplification and over-expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells.

Fan Y, Ge N, Wang X, Sun W, Mao R, Bu W, Creighton CJ, Zheng P, Vasudevan S, An L, Yang J, Zhao YJ, Zhang H, Li XN, Rao PH, Leung E, Lu YJ, Gray JW, Schiff R, Hilsenbeck SG, Osborne CK, Yang J, Zhang H.

J Pathol. 2014 Jan;232(1):75-86. doi: 10.1002/path.4283.

PMID:
24122835
[PubMed - indexed for MEDLINE]
16.

Cancer stem cell markers are enriched in normal tissue adjacent to triple negative breast cancer and inversely correlated with DNA repair deficiency.

Atkinson RL, Yang WT, Rosen DG, Landis MD, Wong H, Lewis MT, Creighton CJ, Sexton KR, Hilsenbeck SG, Sahin AA, Brewster AM, Woodward WA, Chang JC.

Breast Cancer Res. 2013;15(5):R77.

PMID:
24008095
[PubMed - in process]
17.

The role of epithelial-mesenchymal transition programming in invasion and metastasis: a clinical perspective.

Creighton CJ, Gibbons DL, Kurie JM.

Cancer Manag Res. 2013 Jul 31;5:187-95. doi: 10.2147/CMAR.S35171. eCollection 2013.

PMID:
23986650
[PubMed]
Free PMC Article
18.

Tumor grafts derived from patients with head and neck squamous carcinoma authentically maintain the molecular and histologic characteristics of human cancers.

Peng S, Creighton CJ, Zhang Y, Sen B, Mazumdar T, Myers JN, Lai SY, Woolfson A, Lorenzi MV, Bell D, Williams MD, Johnson FM.

J Transl Med. 2013 Aug 27;11:198. doi: 10.1186/1479-5876-11-198. Erratum in: J Transl Med. 2014;12:67. Lai, Stephen Y [added].

PMID:
23981300
[PubMed - in process]
Free PMC Article
19.

Integrative radiogenomic profiling of squamous cell lung cancer.

Abazeed ME, Adams DJ, Hurov KE, Tamayo P, Creighton CJ, Sonkin D, Giacomelli AO, Du C, Fries DF, Wong KK, Mesirov JP, Loeffler JS, Schreiber SL, Hammerman PS, Meyerson M.

Cancer Res. 2013 Oct 15;73(20):6289-98. doi: 10.1158/0008-5472.CAN-13-1616. Epub 2013 Aug 26.

PMID:
23980093
[PubMed - in process]
Free PMC Article
20.

Research resource: progesterone receptor targetome underlying mammary gland branching morphogenesis.

Lain AR, Creighton CJ, Conneely OM.

Mol Endocrinol. 2013 Oct;27(10):1743-61. doi: 10.1210/me.2013-1144. Epub 2013 Aug 26.

PMID:
23979845
[PubMed - in process]

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