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Results: 1 to 20 of 164

1.

Oncogenesis driven by the Ras/Raf pathway requires the SUMO E2 ligase Ubc9.

Yu B, Swatkoski S, Holly A, Lee LC, Giroux V, Lee CS, Hsu D, Smith JL, Yuen G, Yue J, Ann DK, Simpson RM, Creighton CJ, Figg WD, Gucek M, Luo J.

Proc Natl Acad Sci U S A. 2015 Mar 24. pii: 201415569. [Epub ahead of print]

PMID:
25805818
2.

The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers.

Kundu ST, Byers LA, Peng DH, Roybal JD, Diao L, Wang J, Tong P, Creighton CJ, Gibbons DL.

Oncogene. 2015 Mar 23. doi: 10.1038/onc.2015.71. [Epub ahead of print]

PMID:
25798833
3.

ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis.

Liu J, Cho SN, Akkanti B, Jin N, Mao J, Long W, Chen T, Zhang Y, Tang X, Wistub II, Creighton CJ, Kheradmand F, DeMayo FJ.

Cell Rep. 2015 Mar 3. pii: S2211-1247(15)00142-4. doi: 10.1016/j.celrep.2015.02.014. [Epub ahead of print]

4.

Function of phosphorylation of NF-kB p65 ser536 in prostate cancer oncogenesis.

Zhang L, Shao L, Creighton CJ, Zhang Y, Xin L, Ittmann M, Wang J.

Oncotarget. 2015 Jan 31. [Epub ahead of print]

5.

Ex Vivo Four-Dimensional Lung Cancer Model Mimics Metastasis.

Mishra DK, Creighton CJ, Zhang Y, Chen F, Thrall MJ, Kim MP.

Ann Thorac Surg. 2015 Feb 18. pii: S0003-4975(15)00006-5. doi: 10.1016/j.athoracsur.2014.08.085. [Epub ahead of print]

PMID:
25701100
6.

Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma.

Chen Y, Terajima M, Yang Y, Sun L, Ahn YH, Pankova D, Puperi DS, Watanabe T, Kim MP, Blackmon SH, Rodriguez J, Liu H, Behrens C, Wistuba II, Minelli R, Scott KL, Sanchez-Adams J, Guilak F, Pati D, Thilaganathan N, Burns AR, Creighton CJ, Martinez ED, Zal T, Grande-Allen KJ, Yamauchi M, Kurie JM.

J Clin Invest. 2015 Mar 2;125(3):1147-62. doi: 10.1172/JCI74725. Epub 2015 Feb 9.

PMID:
25664850
7.

Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium.

Roarty K, Shore AN, Creighton CJ, Rosen JM.

J Cell Biol. 2015 Feb 2;208(3):351-66. doi: 10.1083/jcb.201408058. Epub 2015 Jan 26.

PMID:
25624393
8.

NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma.

Zhao S, Kurenbekova L, Gao Y, Roos A, Creighton CJ, Rao P, Hicks J, Man TK, Lau C, Brown AM, Jones SN, Lazar AJ, Ingram D, Lev D, Donehower LA, Yustein JT.

Oncogene. 2015 Jan 12. doi: 10.1038/onc.2014.429. [Epub ahead of print]

PMID:
25579177
9.

Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis.

Giuliano M, Herrera S, Christiny P, Shaw C, Creighton CJ, Mitchell T, Bhat R, Zhang X, Mao S, Dobrolecki LE, Al-Rawi A, Chen F, Veneziani BM, Zhang X, Hilsenbeck SG, Contreras A, Gutierrez C, Jeselsohn RM, Rimawi MF, Osborne C, Lewis MT, Schiff R, Trivedi MV.

Breast Cancer Res. 2015 Jan 9;17(1):3. [Epub ahead of print]

10.

In-silico QTL mapping of postpubertal mammary ductal development in the mouse uncovers potential human breast cancer risk loci.

Hadsell DL, Hadsell LA, Olea W, Rijnkels M, Creighton CJ, Smyth I, Short KM, Cox LL, Cox TC.

Mamm Genome. 2015 Feb;26(1-2):57-79. doi: 10.1007/s00335-014-9551-x. Epub 2015 Jan 1.

PMID:
25552398
11.

KAP1 promotes proliferation and metastatic progression of breast cancer cells.

Addison JB, Koontz C, Fugett JH, Creighton CJ, Chen D, Farrugia MK, Padon RR, Voronkova MA, McLaughlin SL, Livengood RH, Lin CC, Ruppert JM, Pugacheva EN, Ivanov AV.

Cancer Res. 2015 Jan 15;75(2):344-55. doi: 10.1158/0008-5472.CAN-14-1561. Epub 2014 Nov 24.

PMID:
25421577
12.

Trans-ancestry mutational landscape of hepatocellular carcinoma genomes.

Totoki Y, Tatsuno K, Covington KR, Ueda H, Creighton CJ, Kato M, Tsuji S, Donehower LA, Slagle BL, Nakamura H, Yamamoto S, Shinbrot E, Hama N, Lehmkuhl M, Hosoda F, Arai Y, Walker K, Dahdouli M, Gotoh K, Nagae G, Gingras MC, Muzny DM, Ojima H, Shimada K, Midorikawa Y, Goss JA, Cotton R, Hayashi A, Shibahara J, Ishikawa S, Guiteau J, Tanaka M, Urushidate T, Ohashi S, Okada N, Doddapaneni H, Wang M, Zhu Y, Dinh H, Okusaka T, Kokudo N, Kosuge T, Takayama T, Fukayama M, Gibbs RA, Wheeler DA, Aburatani H, Shibata T.

Nat Genet. 2014 Dec;46(12):1267-73. doi: 10.1038/ng.3126. Epub 2014 Nov 2.

PMID:
25362482
13.

Stromal TGF-β signaling induces AR activation in prostate cancer.

Yang F, Chen Y, Shen T, Guo D, Dakhova O, Ittmann MM, Creighton CJ, Zhang Y, Dang TD, Rowley DR.

Oncotarget. 2014 Nov 15;5(21):10854-69.

14.

Androgen deprivation-induced NCoA2 promotes metastatic and castration-resistant prostate cancer.

Qin J, Lee HJ, Wu SP, Lin SC, Lanz RB, Creighton CJ, DeMayo FJ, Tsai SY, Tsai MJ.

J Clin Invest. 2014 Nov;124(11):5013-26. doi: 10.1172/JCI76412. Epub 2014 Oct 8.

15.

Functional analysis of miR-34c as a putative tumor suppressor in high-grade serous ovarian cancer.

Yu Z, Kim J, He L, Creighton CJ, Gunaratne PH, Hawkins SM, Matzuk MM.

Biol Reprod. 2014 Nov;91(5):113. doi: 10.1095/biolreprod.114.121988. Epub 2014 Oct 1.

PMID:
25273528
16.

Loss of TRIM62 expression is an independent adverse prognostic factor in acute myeloid leukemia.

Quintás-Cardama A, Zhang N, Qiu YH, Post S, Creighton CJ, Cortes J, Coombes KR, Kornblau SM.

Clin Lymphoma Myeloma Leuk. 2015 Feb;15(2):115-127.e15. doi: 10.1016/j.clml.2014.07.011. Epub 2014 Aug 12.

PMID:
25248926
17.

Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase.

Fu X, Creighton CJ, Biswal NC, Kumar V, Shea M, Herrera S, Contreras A, Gutierrez C, Wang T, Nanda S, Giuliano M, Morrison G, Nardone A, Karlin KL, Westbrook TF, Heiser LM, Anur P, Spellman P, Guichard SM, Smith PD, Davies BR, Klinowska T, Lee AV, Mills GB, Rimawi MF, Hilsenbeck SG, Gray JW, Joshi A, Osborne CK, Schiff R.

Breast Cancer Res. 2014 Sep 11;16(5):430. doi: 10.1186/s13058-014-0430-x.

18.

The somatic genomic landscape of chromophobe renal cell carcinoma.

Davis CF, Ricketts CJ, Wang M, Yang L, Cherniack AD, Shen H, Buhay C, Kang H, Kim SC, Fahey CC, Hacker KE, Bhanot G, Gordenin DA, Chu A, Gunaratne PH, Biehl M, Seth S, Kaipparettu BA, Bristow CA, Donehower LA, Wallen EM, Smith AB, Tickoo SK, Tamboli P, Reuter V, Schmidt LS, Hsieh JJ, Choueiri TK, Hakimi AA; Cancer Genome Atlas Research Network, Chin L, Meyerson M, Kucherlapati R, Park WY, Robertson AG, Laird PW, Henske EP, Kwiatkowski DJ, Park PJ, Morgan M, Shuch B, Muzny D, Wheeler DA, Linehan WM, Gibbs RA, Rathmell WK, Creighton CJ.

Cancer Cell. 2014 Sep 8;26(3):319-30. doi: 10.1016/j.ccr.2014.07.014. Epub 2014 Aug 21.

PMID:
25155756
19.

VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2.

Zhao D, Pan C, Sun J, Gilbert C, Drews-Elger K, Azzam DJ, Picon-Ruiz M, Kim M, Ullmer W, El-Ashry D, Creighton CJ, Slingerland JM.

Oncogene. 2014 Aug 25. doi: 10.1038/onc.2014.257. [Epub ahead of print]

PMID:
25151964
20.

Comprehensive molecular profiling of lung adenocarcinoma.

Cancer Genome Atlas Research Network.

Nature. 2014 Jul 31;511(7511):543-50. doi: 10.1038/nature13385. Epub 2014 Jul 9. Erratum in: Nature. 2014 Oct 9;514(7521):262. Rogers, K [corrected to Rodgers, K].

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