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Items: 1 to 20 of 55


Discovery and SAR of 6-alkyl-2,4-diaminopyrimidines as histamine H₄ receptor antagonists.

Savall BM, Chavez F, Tays K, Dunford PJ, Cowden JM, Hack MD, Wolin RL, Thurmond RL, Edwards JP.

J Med Chem. 2014 Mar 27;57(6):2429-39. doi: 10.1021/jm401727m. Epub 2014 Feb 21.


The histamine H4 receptor mediates inflammation and Th17 responses in preclinical models of arthritis.

Cowden JM, Yu F, Banie H, Farahani M, Ling P, Nguyen S, Riley JP, Zhang M, Zhu J, Dunford PJ, Thurmond RL.

Ann Rheum Dis. 2014 Mar;73(3):600-8. doi: 10.1136/annrheumdis-2013-203832. Epub 2013 Oct 14.


Antagonism of the histamine H4 receptor reduces LPS-induced TNF production in vivo.

Cowden JM, Yu F, Challapalli M, Huang JF, Kim S, Fung-Leung WP, Ma JY, Riley JP, Zhang M, Dunford PJ, Thurmond RL.

Inflamm Res. 2013 Jun;62(6):599-607. doi: 10.1007/s00011-013-0612-5. Epub 2013 Mar 27.


Using sequence data to identify alternative routes and risk of infection: a case-study of campylobacter in Scotland.

Bessell PR, Rotariu O, Innocent GT, Smith-Palmer A, Strachan NJ, Forbes KJ, Cowden JM, Reid SW, Matthews L.

BMC Infect Dis. 2012 Apr 1;12:80. doi: 10.1186/1471-2334-12-80.


An outbreak of food-borne botulism in Scotland, United Kingdom, November 2011.

Browning LM, Prempeh H, Little C, Houston C, Grant K, Cowden JM; United Kingdom Botulism Incident Management Team.

Euro Surveill. 2011 Dec 8;16(49):20036.


Highly virulent Escherichia coli O26, Scotland.

Pollock KG, Bhojani S, Beattie TJ, Allison L, Hanson M, Locking ME, Cowden JM.

Emerg Infect Dis. 2011 Sep;17(9):1777-9. doi: 10.3201/eid1709.110199. No abstract available.


Escherichia coli O157 infection and secondary spread, Scotland, 1999-2008.

Locking ME, Pollock KG, Allison LJ, Rae L, Hanson MF, Cowden JM.

Emerg Infect Dis. 2011 Mar;17(3):524-7. doi: 10.3201/eid1703.100167.


Geographic determinants of reported human Campylobacter infections in Scotland.

Bessell PR, Matthews L, Smith-Palmer A, Rotariu O, Strachan NJ, Forbes KJ, Cowden JM, Reid SW, Innocent GT.

BMC Public Health. 2010 Jul 15;10:423. doi: 10.1186/1471-2458-10-423.


Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines.

Cowden JM, Riley JP, Ma JY, Thurmond RL, Dunford PJ.

Respir Res. 2010 Jun 24;11:86. doi: 10.1186/1465-9921-11-86.


Methods for determining disease burden and calibrating national surveillance data in the United Kingdom: the second study of infectious intestinal disease in the community (IID2 study).

O'Brien SJ, Rait G, Hunter PR, Gray JJ, Bolton FJ, Tompkins DS, McLauchlin J, Letley LH, Adak GK, Cowden JM, Evans MR, Neal KR, Smith GE, Smyth B, Tam CC, Rodrigues LC.

BMC Med Res Methodol. 2010 May 5;10:39. doi: 10.1186/1471-2288-10-39.


Sorbitol-fermenting Escherichia coli O157, Scotland.

Pollock KG, Locking ME, Beattie TJ, Maxwell H, Ramage I, Hughes D, Cowieson J, Allison L, Hanson M, Cowden JM.

Emerg Infect Dis. 2010 May;16(5):881-2. doi: 10.3201/eid1605.091919. No abstract available.


Some haphazard aphorisms for epidemiology and life.

Cowden JM.

Emerg Infect Dis. 2010 Jan;16(1):174-7. No abstract available.


Temperature-dependent transmission of rotavirus in Great Britain and The Netherlands.

Atchison CJ, Tam CC, Hajat S, van Pelt W, Cowden JM, Lopman BA.

Proc Biol Sci. 2010 Mar 22;277(1683):933-42. doi: 10.1098/rspb.2009.1755. Epub 2009 Nov 25.


The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation.

Cowden JM, Zhang M, Dunford PJ, Thurmond RL.

J Invest Dermatol. 2010 Apr;130(4):1023-33. doi: 10.1038/jid.2009.358. Epub 2009 Nov 12.


Overseas outbreaks of infectious intestinal disease identified in Scotland, 2003 to 2007.

Smith-Palmer A, Cowden JM.

J Travel Med. 2009 Sep-Oct;16(5):322-7. doi: 10.1111/j.1708-8305.2009.00323.x.


From diarrhoea to haemolytic uraemic syndrome - when to seek advice.

Pollock KG, Stewart A, Beattie TJ, Todd WT, Ahn CK, Tarr PI, Cowden JM.

J Med Microbiol. 2009 Apr;58(Pt 4):397-8. doi: 10.1099/jmm.0.007179-0. No abstract available.


Campylobacter immunity and coinfection following a large outbreak in a farming community.

Forbes KJ, Gormley FJ, Dallas JF, Labovitiadi O, MacRae M, Owen RJ, Richardson J, Strachan NJ, Cowden JM, Ogden ID, McGuigan CC.

J Clin Microbiol. 2009 Jan;47(1):111-6. doi: 10.1128/JCM.01731-08. Epub 2008 Nov 12.


Letter: Prevention of the spread of infection - the need for a family-centred approach to hygiene promotion.

Pollock K, House R, Cowden JM.

Euro Surveill. 2008 Jun 5;13(23). pii: 18893; author reply pii/18894. No abstract available.


Clinical management of children with suspected or confirmed E. coli O157 infection.

Pollock KG, Beattie TJ, Reynolds B, Stewart A, Cowden JM.

Scott Med J. 2007 Aug;52(3):5-7.

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