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Results: 16

1.

Genetic stability of pneumococcal isolates during 35 days of human experimental carriage.

Gladstone RA, Gritzfeld JF, Coupland P, Gordon SB, Bentley SD.

Vaccine. 2015 Jun 26;33(29):3342-5. doi: 10.1016/j.vaccine.2015.05.021. Epub 2015 May 23.

2.

Single-molecule sequencing reveals the molecular basis of multidrug-resistance in ST772 methicillin-resistant Staphylococcus aureus.

Steinig EJ, Andersson P, Harris SR, Sarovich DS, Manoharan A, Coupland P, Holden MT, Parkhill J, Bentley SD, Robinson DA, Tong SY.

BMC Genomics. 2015 May 16;16:388. doi: 10.1186/s12864-015-1599-9.

3.

G&T-seq: parallel sequencing of single-cell genomes and transcriptomes.

Macaulay IC, Haerty W, Kumar P, Li YI, Hu TX, Teng MJ, Goolam M, Saurat N, Coupland P, Shirley LM, Smith M, Van der Aa N, Banerjee R, Ellis PD, Quail MA, Swerdlow HP, Zernicka-Goetz M, Livesey FJ, Ponting CP, Voet T.

Nat Methods. 2015 Jun;12(6):519-22. doi: 10.1038/nmeth.3370. Epub 2015 Apr 27.

PMID:
25915121
4.

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers.

Shlien A, Campbell BB, de Borja R, Alexandrov LB, Merico D, Wedge D, Van Loo P, Tarpey PS, Coupland P, Behjati S, Pollett A, Lipman T, Heidari A, Deshmukh S, Avitzur N, Meier B, Gerstung M, Hong Y, Merino DM, Ramakrishna M, Remke M, Arnold R, Panigrahi GB, Thakkar NP, Hodel KP, Henninger EE, Göksenin AY, Bakry D, Charames GS, Druker H, Lerner-Ellis J, Mistry M, Dvir R, Grant R, Elhasid R, Farah R, Taylor GP, Nathan PC, Alexander S, Ben-Shachar S, Ling SC, Gallinger S, Constantini S, Dirks P, Huang A, Scherer SW, Grundy RG, Durno C, Aronson M, Gartner A, Meyn MS, Taylor MD, Pursell ZF, Pearson CE, Malkin D, Futreal PA, Stratton MR, Bouffet E, Hawkins C, Campbell PJ, Tabori U; Biallelic Mismatch Repair Deficiency Consortium.

Nat Genet. 2015 Mar;47(3):257-62. doi: 10.1038/ng.3202. Epub 2015 Feb 2.

PMID:
25642631
5.

Bacillary dysentery from World War 1 and NCTC1, the first bacterial isolate in the National Collection.

Mather AE, Baker KS, McGregor H, Coupland P, Mather PL, Deheer-Graham A, Parkhill J, Bracegirdle P, Russell JE, Thomson NR.

Lancet. 2014 Nov 8;384(9955):1720. doi: 10.1016/S0140-6736(14)61790-6. Epub 2014 Nov 7. No abstract available.

PMID:
25441203
6.

The extant World War 1 dysentery bacillus NCTC1: a genomic analysis.

Baker KS, Mather AE, McGregor H, Coupland P, Langridge GC, Day M, Deheer-Graham A, Parkhill J, Russell JE, Thomson NR.

Lancet. 2014 Nov 8;384(9955):1691-7. doi: 10.1016/S0140-6736(14)61789-X. Epub 2014 Nov 7.

7.

Diversification of bacterial genome content through distinct mechanisms over different timescales.

Croucher NJ, Coupland PG, Stevenson AE, Callendrello A, Bentley SD, Hanage WP.

Nat Commun. 2014 Nov 19;5:5471. doi: 10.1038/ncomms6471.

8.

Emergence of scarlet fever Streptococcus pyogenes emm12 clones in Hong Kong is associated with toxin acquisition and multidrug resistance.

Davies MR, Holden MT, Coupland P, Chen JH, Venturini C, Barnett TC, Zakour NL, Tse H, Dougan G, Yuen KY, Walker MJ.

Nat Genet. 2015 Jan;47(1):84-7. doi: 10.1038/ng.3147. Epub 2014 Nov 17.

PMID:
25401300
9.

Transcriptional diversity during lineage commitment of human blood progenitors.

Chen L, Kostadima M, Martens JH, Canu G, Garcia SP, Turro E, Downes K, Macaulay IC, Bielczyk-Maczynska E, Coe S, Farrow S, Poudel P, Burden F, Jansen SB, Astle WJ, Attwood A, Bariana T, de Bono B, Breschi A, Chambers JC; BRIDGE Consortium, Choudry FA, Clarke L, Coupland P, van der Ent M, Erber WN, Jansen JH, Favier R, Fenech ME, Foad N, Freson K, van Geet C, Gomez K, Guigo R, Hampshire D, Kelly AM, Kerstens HH, Kooner JS, Laffan M, Lentaigne C, Labalette C, Martin T, Meacham S, Mumford A, Nürnberg S, Palumbo E, van der Reijden BA, Richardson D, Sammut SJ, Slodkowicz G, Tamuri AU, Vasquez L, Voss K, Watt S, Westbury S, Flicek P, Loos R, Goldman N, Bertone P, Read RJ, Richardson S, Cvejic A, Soranzo N, Ouwehand WH, Stunnenberg HG, Frontini M, Rendon A.

Science. 2014 Sep 26;345(6204):1251033. doi: 10.1126/science.1251033.

10.

Microevolution of Burkholderia pseudomallei during an acute infection.

Limmathurotsakul D, Holden MT, Coupland P, Price EP, Chantratita N, Wuthiekanun V, Amornchai P, Parkhill J, Peacock SJ.

J Clin Microbiol. 2014 Sep;52(9):3418-21. doi: 10.1128/JCM.01219-14. Epub 2014 Jun 25.

11.

Direct sequencing of small genomes on the Pacific Biosciences RS without library preparation.

Coupland P, Chandra T, Quail M, Reik W, Swerdlow H.

Biotechniques. 2012 Dec;53(6):365-72. doi: 10.2144/000113962.

12.

A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers.

Quail MA, Smith M, Coupland P, Otto TD, Harris SR, Connor TR, Bertoni A, Swerdlow HP, Gu Y.

BMC Genomics. 2012 Jul 24;13:341. doi: 10.1186/1471-2164-13-341.

13.

Microfluidics for the upstream pipeline of DNA sequencing--a worthy application?

Coupland P.

Lab Chip. 2010 Mar 7;10(5):544-7. doi: 10.1039/b917560a. Epub 2009 Dec 15.

PMID:
20162226
14.

Using fluorescent pH-sensitive nanosensors to report their intracellular location after Tat-mediated delivery.

Coupland PG, Briddon SJ, Aylott JW.

Integr Biol (Camb). 2009 Apr;1(4):318-23. doi: 10.1039/b822569a. Epub 2009 Mar 3.

PMID:
20023732
15.

Internalisation of polymeric nanosensors in mesenchymal stem cells: analysis by flow cytometry and confocal microscopy.

Coupland PG, Fisher KA, Jones DR, Aylott JW.

J Control Release. 2008 Sep 10;130(2):115-20. doi: 10.1016/j.jconrel.2008.06.018. Epub 2008 Jun 27.

PMID:
18644411
16.

The delivery of PEBBLE nanosensors to measure the intracellular environment.

Webster A, Coupland P, Houghton FD, Leese HJ, Aylott JW.

Biochem Soc Trans. 2007 Jun;35(Pt 3):538-43. Review.

PMID:
17511647
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