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Items: 1 to 20 of 190

1.

ATM protein is deficient in over 40% of lung adenocarcinomas.

Villaruz LC, Jones H, Dacic S, Abberbock S, Kurland BF, Stabile LP, Siegfried JM, Conrads TP, Smith NR, O'Connor MJ, Pierce AJ, Bakkenist CJ.

Oncotarget. 2016 Jun 1. doi: 10.18632/oncotarget.9757. [Epub ahead of print]

2.

Human DNA polymerase ε is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19.

Moiseeva TN, Gamper AM, Hood BL, Conrads TP, Bakkenist CJ.

DNA Repair (Amst). 2016 Jul;43:9-17. doi: 10.1016/j.dnarep.2016.04.007. Epub 2016 May 7.

PMID:
27235625
3.

The Obama Administration's Cancer Moonshot: A Call for Proteomics.

Conrads TP, Petricoin EF.

Clin Cancer Res. 2016 May 19. pii: clincanres.0688.2016. [Epub ahead of print]

PMID:
27199492
4.

Progestins inhibit calcitriol-induced CYP24A1 and synergistically inhibit ovarian cancer cell viability: An opportunity for chemoprevention.

Rodriguez GC, Turbov J, Rosales R, Yoo J, Hunn J, Zappia KJ, Lund K, Barry CP, Rodriguez IV, Pike JW, Conrads TP, Darcy KM, Maxwell GL, Hamilton CA, Syed V, Thaete LG.

Gynecol Oncol. 2016 Apr 19. pii: S0090-8258(16)30154-8. doi: 10.1016/j.ygyno.2016.04.022. [Epub ahead of print]

PMID:
27106018
5.

Nestin: A biomarker of aggressive uterine cancers.

Hope ER, Mhawech-Fauceglia P, Pejovic T, Zahn CM, Wang G, Conrads TP, Larry Maxwell G, Hamilton CA, Darcy KM, Syed V.

Gynecol Oncol. 2016 Mar;140(3):503-11. doi: 10.1016/j.ygyno.2015.12.015. Epub 2015 Dec 21.

PMID:
26718725
6.

Identification and functional characterization of a novel bipartite nuclear localization sequence in ARID1A.

Bateman NW, Shoji Y, Conrads KA, Stroop KD, Hamilton CA, Darcy KM, Maxwell GL, Risinger JI, Conrads TP.

Biochem Biophys Res Commun. 2016 Jan 1;469(1):114-9. doi: 10.1016/j.bbrc.2015.11.080. Epub 2015 Nov 22.

PMID:
26614907
7.

The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo.

Vendetti FP, Lau A, Schamus S, Conrads TP, O'Connor MJ, Bakkenist CJ.

Oncotarget. 2015 Dec 29;6(42):44289-305. doi: 10.18632/oncotarget.6247.

8.

Label-Free LC-MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis.

Collins MA, An J, Hood BL, Conrads TP, Bowser RP.

J Proteome Res. 2015 Nov 6;14(11):4486-501. doi: 10.1021/acs.jproteome.5b00804. Epub 2015 Oct 8.

PMID:
26401960
9.

BRCA1 deficiency in ovarian cancer is associated with alteration in expression of several key regulators of cell motility - A proteomics study.

Gau DM, Lesnock JL, Hood BL, Bhargava R, Sun M, Darcy K, Luthra S, Chandran U, Conrads TP, Edwards RP, Kelley JL, Krivak TC, Roy P.

Cell Cycle. 2015;14(12):1884-92. doi: 10.1080/15384101.2015.1036203.

10.

Elevated AKAP12 in paclitaxel-resistant serous ovarian cancer cells is prognostic and predictive of poor survival in patients.

Bateman NW, Jaworski E, Ao W, Wang G, Litzi T, Dubil E, Marcus C, Conrads KA, Teng PN, Hood BL, Phippen NT, Vasicek LA, McGuire WP, Paz K, Sidransky D, Hamilton CA, Maxwell GL, Darcy KM, Conrads TP.

J Proteome Res. 2015 Apr 3;14(4):1900-10. doi: 10.1021/pr5012894. Epub 2015 Mar 19.

11.

Proteomics of the human endometrial glandular epithelium and stroma from the proliferative and secretory phases of the menstrual cycle.

Hood BL, Liu B, Alkhas A, Shoji Y, Challa R, Wang G, Ferguson S, Oliver J, Mitchell D, Bateman NW, Zahn CM, Hamilton CA, Payson M, Lessey B, Fazleabas AT, Maxwell GL, Conrads TP, Risinger JI.

Biol Reprod. 2015 Apr;92(4):106. doi: 10.1095/biolreprod.114.127217. Epub 2015 Feb 18.

12.

The assembly of miRNA-mRNA-protein regulatory networks using high-throughput expression data.

Chu T, Mouillet JF, Hood BL, Conrads TP, Sadovsky Y.

Bioinformatics. 2015 Jun 1;31(11):1780-7. doi: 10.1093/bioinformatics/btv038. Epub 2015 Jan 24.

13.

Pharmacologic inhibition of ATR and ATM offers clinically important distinctions to enhancing platinum or radiation response in ovarian, endometrial, and cervical cancer cells.

Teng PN, Bateman NW, Darcy KM, Hamilton CA, Maxwell GL, Bakkenist CJ, Conrads TP.

Gynecol Oncol. 2015 Mar;136(3):554-61. doi: 10.1016/j.ygyno.2014.12.035. Epub 2015 Jan 2.

14.

MicroRNAs in endometrial cancers from black and white patients.

Maxwell GL, Shoji Y, Darcy K, Litzi T, Berchuck A, Hamilton CA, Conrads TP, Risinger JI.

Am J Obstet Gynecol. 2015 Feb;212(2):191.e1-10. doi: 10.1016/j.ajog.2014.08.028. Epub 2014 Aug 28.

PMID:
25174797
15.

Evaluation of a 4-protein serum biomarker panel-biglycan, annexin-A6, myeloperoxidase, and protein S100-A9 (B-AMP)-for the detection of esophageal adenocarcinoma.

Zaidi AH, Gopalakrishnan V, Kasi PM, Zeng X, Malhotra U, Balasubramanian J, Visweswaran S, Sun M, Flint MS, Davison JM, Hood BL, Conrads TP, Bergman JJ, Bigbee WL, Jobe BA.

Cancer. 2014 Dec 15;120(24):3902-13. doi: 10.1002/cncr.28963. Epub 2014 Aug 5.

16.

Extrinsic apoptosis is impeded by direct binding of the APL fusion protein NPM-RAR to TRADD.

Chattopadhyay A, Hood BL, Conrads TP, Redner RL.

Mol Cancer Res. 2014 Sep;12(9):1283-91. doi: 10.1158/1541-7786.MCR-14-0080. Epub 2014 Jul 17.

17.

COX-2 inhibition potentiates antiangiogenic cancer therapy and prevents metastasis in preclinical models.

Xu L, Stevens J, Hilton MB, Seaman S, Conrads TP, Veenstra TD, Logsdon D, Morris H, Swing DA, Patel NL, Kalen J, Haines DC, Zudaire E, St Croix B.

Sci Transl Med. 2014 Jun 25;6(242):242ra84. doi: 10.1126/scitranslmed.3008455.

18.

Erlotinib, erlotinib-sulindac versus placebo: a randomized, double-blind, placebo-controlled window trial in operable head and neck cancer.

Gross ND, Bauman JE, Gooding WE, Denq W, Thomas SM, Wang L, Chiosea S, Hood BL, Flint MS, Sun M, Conrads TP, Ferris RL, Johnson JT, Kim S, Argiris A, Wirth L, Nikiforova MN, Siegfried JM, Grandis JR.

Clin Cancer Res. 2014 Jun 15;20(12):3289-98. doi: 10.1158/1078-0432.CCR-13-3360. Epub 2014 Apr 11.

19.

Choline phosphate cytidylyltransferase-α is a novel antigen detected by the anti-ERCC1 antibody 8F1 with biomarker value in patients with lung and head and neck squamous cell carcinomas.

Vaezi AE, Bepler G, Bhagwat NR, Malysa A, Rubatt JM, Chen W, Hood BL, Conrads TP, Wang L, Kemp CE, Niedernhofer LJ.

Cancer. 2014 Jun 15;120(12):1898-907. doi: 10.1002/cncr.28643. Epub 2014 Apr 1.

20.

Identification of candidate circulating cisplatin-resistant biomarkers from epithelial ovarian carcinoma cell secretomes.

Teng PN, Wang G, Hood BL, Conrads KA, Hamilton CA, Maxwell GL, Darcy KM, Conrads TP.

Br J Cancer. 2014 Jan 7;110(1):123-32. doi: 10.1038/bjc.2013.687. Epub 2013 Oct 31.

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