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Results: 1 to 20 of 98

1.

Automated video-based analysis of contractility and calcium flux in human iPS-derived cardiomyocytes cultured over different spatial scales.

Huebsch N, Loskill P, Mandegar MA, Marks NC, Sheehan AS, Ma Z, Mathur AA, Nguyen TN, Yoo JC, Judge LM, Spencer CI, Chukka A, Russell CR, So PL, Conklin BR, Healy KE.

Tissue Eng Part C Methods. 2014 Oct 21. [Epub ahead of print]

PMID:
25333967
[PubMed - as supplied by publisher]
2.

Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia.

Spencer CI, Baba S, Nakamura K, Hua EA, Sears MA, Fu CC, Zhang J, Balijepalli S, Tomoda K, Hayashi Y, Lizarraga P, Wojciak J, Scheinman MM, Aalto-Setälä K, Makielski JC, January CT, Healy KE, Kamp TJ, Yamanaka S, Conklin BR.

Stem Cell Reports. 2014 Aug 12;3(2):269-81. doi: 10.1016/j.stemcr.2014.06.003. Epub 2014 Jul 4.

PMID:
25254341
[PubMed - in process]
Free PMC Article
3.

Synthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signal.

Park JS, Rhau B, Hermann A, McNally KA, Zhou C, Gong D, Weiner OD, Conklin BR, Onuffer J, Lim WA.

Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):5896-901. doi: 10.1073/pnas.1402087111. Epub 2014 Apr 7.

PMID:
24711398
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development.

Mathur A, Loskill P, Hong S, Lee J, Marcus SG, Dumont L, Conklin BR, Willenbring H, Lee LP, Healy KE.

Stem Cell Res Ther. 2013;4 Suppl 1:S14. doi: 10.1186/scrt375. Epub 2013 Dec 20. Review.

PMID:
24565415
[PubMed - indexed for MEDLINE]
5.

Isolation of single-base genome-edited human iPS cells without antibiotic selection.

Miyaoka Y, Chan AH, Judge LM, Yoo J, Huang M, Nguyen TD, Lizarraga PP, So PL, Conklin BR.

Nat Methods. 2014 Mar;11(3):291-3. doi: 10.1038/nmeth.2840. Epub 2014 Feb 9.

PMID:
24509632
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation.

Matsumoto Y, Hayashi Y, Schlieve CR, Ikeya M, Kim H, Nguyen TD, Sami S, Baba S, Barruet E, Nasu A, Asaka I, Otsuka T, Yamanaka S, Conklin BR, Toguchida J, Hsiao EC.

Orphanet J Rare Dis. 2013 Dec 9;8:190. doi: 10.1186/1750-1172-8-190.

PMID:
24321451
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Three-dimensional filamentous human diseased cardiac tissue model.

Ma Z, Koo S, Finnegan MA, Loskill P, Huebsch N, Marks NC, Conklin BR, Grigoropoulos CP, Healy KE.

Biomaterials. 2014 Feb;35(5):1367-77. doi: 10.1016/j.biomaterials.2013.10.052. Epub 2013 Nov 21.

PMID:
24268663
[PubMed - indexed for MEDLINE]
8.

The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy.

Taglieri DM, Johnson KR, Burmeister BT, Monasky MM, Spindler MJ, DeSantiago J, Banach K, Conklin BR, Carnegie GK.

J Mol Cell Cardiol. 2014 Jan;66:27-40. doi: 10.1016/j.yjmcc.2013.10.010. Epub 2013 Oct 23.

PMID:
24161911
[PubMed - indexed for MEDLINE]
9.

Sculpting genomes with a hammer and chisel.

Conklin BR.

Nat Methods. 2013 Sep;10(9):839-40. doi: 10.1038/nmeth.2608. No abstract available.

PMID:
23985729
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A robust method to derive functional neural crest cells from human pluripotent stem cells.

Kreitzer FR, Salomonis N, Sheehan A, Huang M, Park JS, Spindler MJ, Lizarraga P, Weiss WA, So PL, Conklin BR.

Am J Stem Cells. 2013 Jun 30;2(2):119-31. Print 2013.

PMID:
23862100
[PubMed]
Free PMC Article
11.

AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophy.

Spindler MJ, Burmeister BT, Huang Y, Hsiao EC, Salomonis N, Scott MJ, Srivastava D, Carnegie GK, Conklin BR.

PLoS One. 2013 Apr 26;8(4):e62705. doi: 10.1371/journal.pone.0062705. Print 2013.

PMID:
23658642
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Structure of a novel winged-helix like domain from human NFRKB protein.

Kumar A, Möcklinghoff S, Yumoto F, Jaroszewski L, Farr CL, Grzechnik A, Nguyen P, Weichenberger CX, Chiu HJ, Klock HE, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Conklin BR, Fletterick RJ, Wilson IA.

PLoS One. 2012;7(9):e43761. doi: 10.1371/journal.pone.0043761. Epub 2012 Sep 11.

PMID:
22984442
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells.

Tomoda K, Takahashi K, Leung K, Okada A, Narita M, Yamada NA, Eilertson KE, Tsang P, Baba S, White MP, Sami S, Srivastava D, Conklin BR, Panning B, Yamanaka S.

Cell Stem Cell. 2012 Jul 6;11(1):91-9. doi: 10.1016/j.stem.2012.05.019.

PMID:
22770243
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

GO-Elite: a flexible solution for pathway and ontology over-representation.

Zambon AC, Gaj S, Ho I, Hanspers K, Vranizan K, Evelo CT, Conklin BR, Pico AR, Salomonis N.

Bioinformatics. 2012 Aug 15;28(16):2209-10. doi: 10.1093/bioinformatics/bts366. Epub 2012 Jun 27.

PMID:
22743224
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

WikiPathways: building research communities on biological pathways.

Kelder T, van Iersel MP, Hanspers K, Kutmon M, Conklin BR, Evelo CT, Pico AR.

Nucleic Acids Res. 2012 Jan;40(Database issue):D1301-7. doi: 10.1093/nar/gkr1074. Epub 2011 Nov 16.

PMID:
22096230
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture.

Lahti AL, Kujala VJ, Chapman H, Koivisto AP, Pekkanen-Mattila M, Kerkelä E, Hyttinen J, Kontula K, Swan H, Conklin BR, Yamanaka S, Silvennoinen O, Aalto-Setälä K.

Dis Model Mech. 2012 Mar;5(2):220-30. doi: 10.1242/dmm.008409. Epub 2011 Nov 3.

PMID:
22052944
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Mineral composition is altered by osteoblast expression of an engineered G(s)-coupled receptor.

Kazakia GJ, Speer D, Shanbhag S, Majumdar S, Conklin BR, Nissenson RA, Hsiao EC.

Calcif Tissue Int. 2011 Jul;89(1):10-20. doi: 10.1007/s00223-011-9487-z. Epub 2011 Apr 28.

PMID:
21526395
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Constitutive Gs activation using a single-construct tetracycline-inducible expression system in embryonic stem cells and mice.

Hsiao EC, Nguyen TD, Ng JK, Scott MJ, Chang WC, Zahed H, Conklin BR.

Stem Cell Res Ther. 2011 Mar 4;2(2):11. doi: 10.1186/scrt52.

PMID:
21375737
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Blockade of receptor-activated G(i) signaling in osteoblasts in vivo leads to site-specific increases in cortical and cancellous bone formation.

Millard SM, Louie AM, Wattanachanya L, Wronski TJ, Conklin BR, Nissenson RA.

J Bone Miner Res. 2011 Apr;26(4):822-32. doi: 10.1002/jbmr.273.

PMID:
20939063
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Finding the right questions: exploratory pathway analysis to enhance biological discovery in large datasets.

Kelder T, Conklin BR, Evelo CT, Pico AR.

PLoS Biol. 2010 Aug 31;8(8). pii: e1000472. doi: 10.1371/journal.pbio.1000472.

PMID:
20824171
[PubMed - indexed for MEDLINE]
Free PMC Article
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