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Results: 1 to 20 of 78

1.

Vaginal pH and microbicidal lactic acid when lactobacilli dominate the microbiota.

O'Hanlon DE, Moench TR, Cone RA.

PLoS One. 2013 Nov 6;8(11):e80074. doi: 10.1371/journal.pone.0080074. eCollection 2013.

PMID:
24223212
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Drug-induced reactivation of apoptosis abrogates HIV-1 infection.

Hanauske-Abel HM, Saxena D, Palumbo PE, Hanauske AR, Luchessi AD, Cambiaghi TD, Hoque M, Spino M, D'Alliessi Gandolfi D, Heller DS, Singh S, Park MH, Cracchiolo BM, Tricta F, Connelly J, Popowicz AM, Cone RA, Holland B, Pe'ery T, Mathews MB.

PLoS One. 2013 Sep 23;8(9):e74414. doi: 10.1371/journal.pone.0074414. eCollection 2013.

PMID:
24086341
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Enhanced vaginal drug delivery through the use of hypotonic formulations that induce fluid uptake.

Ensign LM, Hoen TE, Maisel K, Cone RA, Hanes JS.

Biomaterials. 2013 Sep;34(28):6922-9. doi: 10.1016/j.biomaterials.2013.05.039. Epub 2013 Jun 13.

PMID:
23769419
[PubMed - indexed for MEDLINE]
4.

Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo.

Xu Q, Boylan NJ, Suk JS, Wang YY, Nance EA, Yang JC, McDonnell PJ, Cone RA, Duh EJ, Hanes J.

J Control Release. 2013 Apr 10;167(1):76-84. doi: 10.1016/j.jconrel.2013.01.018. Epub 2013 Jan 28.

PMID:
23369761
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Evaluation of microbicide gel adherence monitoring methods.

Moench TR, O'Hanlon DE, Cone RA.

Sex Transm Dis. 2012 May;39(5):335-40. doi: 10.1097/OLQ.0b013e31824790bb.

PMID:
22504592
[PubMed - indexed for MEDLINE]
6.

In vaginal fluid, bacteria associated with bacterial vaginosis can be suppressed with lactic acid but not hydrogen peroxide.

O'Hanlon DE, Moench TR, Cone RA.

BMC Infect Dis. 2011 Jul 19;11:200. doi: 10.1186/1471-2334-11-200.

PMID:
21771337
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Novel approaches to vaginal delivery and safety of microbicides: biopharmaceuticals, nanoparticles, and vaccines.

Whaley KJ, Hanes J, Shattock R, Cone RA, Friend DR.

Antiviral Res. 2010 Dec;88 Suppl 1:S55-66. doi: 10.1016/j.antiviral.2010.09.006.

PMID:
21109069
[PubMed - indexed for MEDLINE]
8.

Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse.

Moench TR, Mumper RJ, Hoen TE, Sun M, Cone RA.

BMC Infect Dis. 2010 Nov 18;10:331. doi: 10.1186/1471-2334-10-331.

PMID:
21087496
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Rapid fluctuation of the vaginal microbiota measured by Gram stain analysis.

Brotman RM, Ravel J, Cone RA, Zenilman JM.

Sex Transm Infect. 2010 Aug;86(4):297-302. doi: 10.1136/sti.2009.040592.

PMID:
20660593
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Cervicovaginal fluid and semen block the microbicidal activity of hydrogen peroxide produced by vaginal lactobacilli.

O'Hanlon DE, Lanier BR, Moench TR, Cone RA.

BMC Infect Dis. 2010 May 19;10:120. doi: 10.1186/1471-2334-10-120.

PMID:
20482854
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Barrier properties of mucus.

Cone RA.

Adv Drug Deliv Rev. 2009 Feb 27;61(2):75-85. doi: 10.1016/j.addr.2008.09.008. Epub 2008 Dec 16. Review.

PMID:
19135107
[PubMed - indexed for MEDLINE]
12.

Formulating a sulfonated antiviral dendrimer in a vaginal microbicidal gel having dual mechanisms of action.

Mumper RJ, Bell MA, Worthen DR, Cone RA, Lewis GR, Paull JR, Moench TR.

Drug Dev Ind Pharm. 2009 May;35(5):515-24. doi: 10.1080/03639040802488097.

PMID:
19040181
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission.

Cone RA, Hoen T, Wong X, Abusuwwa R, Anderson DJ, Moench TR.

BMC Infect Dis. 2006 Jun 1;6:90.

PMID:
16740164
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Low pH immobilizes and kills human leukocytes and prevents transmission of cell-associated HIV in a mouse model.

Olmsted SS, Khanna KV, Ng EM, Whitten ST, Johnson ON 3rd, Markham RB, Cone RA, Moench TR.

BMC Infect Dis. 2005 Sep 30;5:79.

PMID:
16194280
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A self-sampling method to obtain large volumes of undiluted cervicovaginal secretions.

Boskey ER, Moench TR, Hees PS, Cone RA.

Sex Transm Dis. 2003 Feb;30(2):107-9.

PMID:
12567165
[PubMed - indexed for MEDLINE]
16.

Microbicide efficacy and toxicity tests in a mouse model for vaginal transmission of Chlamydia trachomatis.

Achilles SL, Shete PB, Whaley KJ, Moench TR, Cone RA.

Sex Transm Dis. 2002 Nov;29(11):655-64.

PMID:
12438901
[PubMed - indexed for MEDLINE]
17.

Human monoclonal antibody stability and activity at vaginal pH.

Castle PE, Karp DA, Zeitlin L, GarcĂ­a-Moreno E B, Moench TR, Whaley KJ, Cone RA.

J Reprod Immunol. 2002 Jul-Aug;56(1-2):61-76.

PMID:
12106884
[PubMed - indexed for MEDLINE]
18.

Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent.

Khanna KV, Whaley KJ, Zeitlin L, Moench TR, Mehrazar K, Cone RA, Liao Z, Hildreth JE, Hoen TE, Shultz L, Markham RB.

J Clin Invest. 2002 Jan;109(2):205-11.

PMID:
11805132
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Diffusion of macromolecules and virus-like particles in human cervical mucus.

Olmsted SS, Padgett JL, Yudin AI, Whaley KJ, Moench TR, Cone RA.

Biophys J. 2001 Oct;81(4):1930-7.

PMID:
11566767
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Origins of vaginal acidity: high D/L lactate ratio is consistent with bacteria being the primary source.

Boskey ER, Cone RA, Whaley KJ, Moench TR.

Hum Reprod. 2001 Sep;16(9):1809-13.

PMID:
11527880
[PubMed - indexed for MEDLINE]
Free Article

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