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1964 1
1965 1
1966 1
1968 3
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1970 1
1971 1
1972 2
1973 2
1974 2
1975 20
1976 10
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1978 12
1979 20
1980 17
1981 19
1982 14
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1984 35
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1987 37
1988 26
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1996 67
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1998 90
1999 91
2000 125
2001 144
2002 137
2003 203
2004 215
2005 225
2006 237
2007 238
2008 241
2009 278
2010 352
2011 356
2012 373
2013 390
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2015 440
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2023 449
2024 165

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8,390 results

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Screening of AS101 analog, organotellurolate (IV) compound 2 for its in vitro biocompatibility, anticancer, and antibacterial activities.
Tripathi A, Khan A, Kiran P, Shetty H, Srivastava R. Tripathi A, et al. Amino Acids. 2023 Jul;55(7):891-902. doi: 10.1007/s00726-023-03280-7. Epub 2023 May 25. Amino Acids. 2023. PMID: 37227510
The fibroblast cells with good viability confirmed the biocompatibility, and compound 2 also was less hemolytic on RBCs. A cytotoxic effect on MCF-7 breast cancer cell line investigated compound 2 to be anti-cancerous with IC50 value of 2.86 0.02 g/mL. …
The fibroblast cells with good viability confirmed the biocompatibility, and compound 2 also was less hemolytic on RBCs. A cyt …
The Compound 2-Hexyl, 5-Propyl Resorcinol Has a Key Role in Biofilm Formation by the Biocontrol Rhizobacterium Pseudomonas chlororaphis PCL1606.
Calderón CE, Tienda S, Heredia-Ponce Z, Arrebola E, Cárcamo-Oyarce G, Eberl L, Cazorla FM. Calderón CE, et al. Front Microbiol. 2019 Feb 28;10:396. doi: 10.3389/fmicb.2019.00396. eCollection 2019. Front Microbiol. 2019. PMID: 30873149 Free PMC article.
The production of the compound 2-hexyl-5-propyl resorcinol (HPR) by the biocontrol rhizobacterium Pseudomonas chlororaphis PCL1606 (PcPCL1606) is crucial for fungal antagonism and biocontrol activity that protects plants against the phytopathogenic fungus Rosellinia …
The production of the compound 2-hexyl-5-propyl resorcinol (HPR) by the biocontrol rhizobacterium Pseudomonas chlororaphis PCL …
A Neutral Planar Four-Membered Si2B2 2π-Aromatic Ring.
Kushvaha SK, Kallenbach P, Rohman SS, Pandey MK, Hendi Z, Rüttger F, Herbst-Irmer R, Stalke D, Parameswaran P, Roesky HW. Kushvaha SK, et al. J Am Chem Soc. 2023 Nov 29;145(47):25523-25527. doi: 10.1021/jacs.3c09131. Epub 2023 Nov 7. J Am Chem Soc. 2023. PMID: 37934173
The synthesis of the first inorganic four-membered neutral 2pi-aromatic compound 2 is reported. This unique ring has been synthesized from a simple and straightforward reaction of amidinato-silylene with dichlorophenylborane, followed by the reduction with KC(8) in …
The synthesis of the first inorganic four-membered neutral 2pi-aromatic compound 2 is reported. This unique ring has been synt …
Discovery of 14S-(2'-chloro-4'-nitrophenoxy)-8R/S,17-epoxy andrographolide as EV-A71 infection inhibitor.
Dai K, Tan JK, Qian W, Lee RCH, Hann Chu JJ, Zhou GC. Dai K, et al. Biochem Pharmacol. 2021 Dec;194:114820. doi: 10.1016/j.bcp.2021.114820. Epub 2021 Nov 5. Biochem Pharmacol. 2021. PMID: 34748818
It is revealed that compound 2 inhibits the post-entry stages of EV-A71 viral replication cycle and significantly reduces viral protein expression of structural proteins such as VP0 and VP2 via inhibiting EV-A71 RNA replication. Moreover, the inhibitory property of …
It is revealed that compound 2 inhibits the post-entry stages of EV-A71 viral replication cycle and significantly reduces vira …
(1R*,2R*)-1,2-(2,3-Dimethoxybutane-2,3-dioxy)cyclohexane.
Weinig HG, Koert U, Ziemer B. Weinig HG, et al. Acta Crystallogr C. 2000 May 15;56(Pt 5):E218. doi: 10.1107/S0108270100005485. Epub 2000 May 15. Acta Crystallogr C. 2000. PMID: 15263159
The title compound, 2,3-dimethoxy-2,3-dimethyl-5,6,7,8-tetrahydro-4-oxachroman, C(12)H(22)O(4), was synthesized as a model compound for substituted diequatorial fixed vicinal trans-cyclohexanediols....
The title compound, 2,3-dimethoxy-2,3-dimethyl-5,6,7,8-tetrahydro-4-oxachroman, C(12)H(22)O(4), was synthesized as a model com …
Dimensions of Caregiver Burden between Compound and Noncompound Caregivers of Adults with Autism.
Marsack-Topolewski CN, Wang F. Marsack-Topolewski CN, et al. J Gerontol Soc Work. 2022 May-Jun;65(4):402-420. doi: 10.1080/01634372.2021.1969609. Epub 2021 Aug 24. J Gerontol Soc Work. 2022. PMID: 34427543
The present study aims to compare differences between compound 1, compound 2, and noncompound caregivers on specific dimensions of caregiver burden associated with adult children with ASD. ...Compound 1 and noncompound caregivers experienced lower levels of time dep …
The present study aims to compare differences between compound 1, compound 2, and noncompound caregivers on specific dimension …
In Vitro Pharmacological Profile of a New Small Molecule Bradykinin B2 Receptor Antagonist.
Lesage A, Gibson C, Marceau F, Ambrosi HD, Saupe J, Katzer W, Loenders B, Charest-Morin X, Knolle J. Lesage A, et al. Front Pharmacol. 2020 Jun 19;11:916. doi: 10.3389/fphar.2020.00916. eCollection 2020. Front Pharmacol. 2020. PMID: 32636746 Free PMC article.
We here report the discovery and early characterization of Compound 3, a representative of a novel class of small molecule bradykinin (BK) B(2) receptor antagonists, and its superior profile to the prior art B(2) receptor antagonists Compound 1 and Compound 2. Compo …
We here report the discovery and early characterization of Compound 3, a representative of a novel class of small molecule bradykinin (BK) B …
2-[(4-Benzhydrylpipérazin-1-yl)méthyl]acrylonitrile.
Ben Amor F, Ould M'hamed M, Mrabet H, Driss A, Efrit ML. Ben Amor F, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 Sep 6;64(Pt 10):o1872. doi: 10.1107/S1600536808025403. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21201087 Free PMC article.
In the title compound, 2-[(4-benz-hydryl-piperazin-1-yl)-methyl]-acrylo-nitrile, C(21)H(23)N(3), the substituted piperazine ring adopts a chair conformation and the dihedral angle between the mean planes of the aromatic rings is 71.61 (8)....
In the title compound, 2-[(4-benz-hydryl-piperazin-1-yl)-methyl]-acrylo-nitrile, C(21)H(23)N(3), the substituted piperazine ri …
From hydrated Ni3(OH)2(C8H4O4)2(H2O)4 to anhydrous Ni2(OH)2(C8H4O4): impact of structural transformations on magnetic properties.
Mesbah A, Rabu P, Sibille R, Lebègue S, Mazet T, Malaman B, François M. Mesbah A, et al. Inorg Chem. 2014 Jan 21;53(2):872-81. doi: 10.1021/ic402106v. Epub 2014 Jan 8. Inorg Chem. 2014. PMID: 24400955
It was shown that at T1 (433 K) the infinite nickel oxide chains built of the repeating structural unit [Ni3(mu3-OH)2](4+) in 1 collapse and lead to infinite porous layers, forming compound 2. The second transformation at T2 (483 K) gave the expected anhydrous compo …
It was shown that at T1 (433 K) the infinite nickel oxide chains built of the repeating structural unit [Ni3(mu3-OH)2](4+) in 1 collapse and …
The angiogenesis-modulating effects of coumarin-derivatives.
Huang HT, Huang CY, Lee CJ, Sun BJ, Jhang ZW, Wen CC, Wang YH, Li TS, Chern CY, Chen YH. Huang HT, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2024 Apr;278:109862. doi: 10.1016/j.cbpc.2024.109862. Epub 2024 Feb 19. Comp Biochem Physiol C Toxicol Pharmacol. 2024. PMID: 38382586
Chick chorioallantoic membrane (CAM) assay also showed that Compound #2 exposure led to a reduction of blood vessel growth. Real-time PCR experiments revealed that Compound #2 significantly changed the expression of vascular growth-related genes flt1, …
Chick chorioallantoic membrane (CAM) assay also showed that Compound #2 exposure led to a reduction of blood vessel growth. Re …
8,390 results