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Year Number of Results
2004 2
2005 1
2006 5
2007 3
2008 1
2009 4
2010 4
2011 5
2012 2
2013 1
2014 1
2015 3
2016 4
2017 4
2018 4
2019 3
2020 4
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2023 2
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54 results

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Page 1
Correlation of histology and linear and nonlinear microscopy of the living human cornea.
Masters BR. Masters BR. J Biophotonics. 2009 Mar;2(3):127-39. doi: 10.1002/jbio.200810039. J Biophotonics. 2009. PMID: 19343693 Review.
Second-harmonic generation microscopy, a scattering process that does not deposit net energy into the tissue, provides structural information on corneal collagen organization. ...Coherent anti-Stokes Raman scattering microscopy provides chemical imaging for b …
Second-harmonic generation microscopy, a scattering process that does not deposit net energy into the tissue, provides structural inf …
A Custom Multiphoton Microscopy Platform for Live Imaging of Mouse Cornea and Conjunctiva.
Wu YF, Ye RT, Pan MK, Lin SJ, Tan HY. Wu YF, et al. J Vis Exp. 2020 May 17;(159). doi: 10.3791/60944. J Vis Exp. 2020. PMID: 32478739
Conventional histological analysis and cell culture systems are insufficient to simulate in vivo physiological and pathological dynamics completely. Multiphoton microscopy (MPM) has become one of the most popular imaging modalities for biomedical study at cellular l …
Conventional histological analysis and cell culture systems are insufficient to simulate in vivo physiological and pathological dynamics com …
Revisiting the Cornea and Trabecular Meshwork Junction With 2-Photon Excitation Fluorescence Microscopy.
Marando CM, Park CY, Liao JA, Lee JK, Chuck RS. Marando CM, et al. Cornea. 2017 Jun;36(6):704-711. doi: 10.1097/ICO.0000000000001178. Cornea. 2017. PMID: 28368994
PURPOSE: To investigate the collagen and elastin architecture at the junction of the human cornea and trabecular meshwork (TM). ...The CB tendons directly abut DM, and their insertion narrows as they course centrally in the cornea, giving a wedge appearance t …
PURPOSE: To investigate the collagen and elastin architecture at the junction of the human cornea and trabecular meshwork (TM) …
Two-Photon Imaging for Non-Invasive Corneal Examination.
Batista A, Guimarães P, Domingues JP, Quadrado MJ, Morgado AM. Batista A, et al. Sensors (Basel). 2022 Dec 11;22(24):9699. doi: 10.3390/s22249699. Sensors (Basel). 2022. PMID: 36560071 Free PMC article. Review.
These modalities rely on different contrast mechanisms and are often used simultaneously to provide complementary information on morphology, metabolism, and structural properties of the imaged tissue. The cornea, being a transparent tissue, rich in collagen and with …
These modalities rely on different contrast mechanisms and are often used simultaneously to provide complementary information on morphology, …
Evolution of the vertebrate corneal stroma.
Koudouna E, Winkler M, Mikula E, Juhasz T, Brown DJ, Jester JV. Koudouna E, et al. Prog Retin Eye Res. 2018 May;64:65-76. doi: 10.1016/j.preteyeres.2018.01.002. Epub 2018 Feb 2. Prog Retin Eye Res. 2018. PMID: 29398348 Review.
Although the cornea is the major refractive element of the eye, the mechanisms controlling corneal shape and hence visual acuity remain unknown. To begin to address this question we have used multiphoton, non-linear optical microscopy to image second h …
Although the cornea is the major refractive element of the eye, the mechanisms controlling corneal shape and hence visual acui …
Long-Term Intravital Imaging of the Cornea, Skin, and Hair Follicle by Multiphoton Microscope.
Wu YF, Tan HY, Lin SJ. Wu YF, et al. Methods Mol Biol. 2020;2150:131-140. doi: 10.1007/7651_2019_227. Methods Mol Biol. 2020. PMID: 30969402
Multiphoton microscopy allows long-term direct visualization of cells in live animals due to its low photodamage. ...Here, we demonstrate cell imaging and tracing at a single cell resolution in the cornea, skin, and hair follicles using multiphoton …
Multiphoton microscopy allows long-term direct visualization of cells in live animals due to its low photodamage. ...Here, we …
Multiphoton microscopy of ex vivo corneas after collagen cross-linking.
Bueno JM, Gualda EJ, Giakoumaki A, Pérez-Merino P, Marcos S, Artal P. Bueno JM, et al. Invest Ophthalmol Vis Sci. 2011 Jul 18;52(8):5325-31. doi: 10.1167/iovs.11-7184. Invest Ophthalmol Vis Sci. 2011. PMID: 21467175
CXL changed the collagen distribution pattern showing some abnormal structures. TPEF revealed a large reduction in corneal thickness in CXL corneas immediately after treatment. The changes in the distribution of collagen bundles appeared also in corneas …
CXL changed the collagen distribution pattern showing some abnormal structures. TPEF revealed a large reduction in corneal thickness …
Multiphoton autofluorescence and second-harmonic generation imaging of the ex vivo porcine eye.
Teng SW, Tan HY, Peng JL, Lin HH, Kim KH, Lo W, Sun Y, Lin WC, Lin SJ, Jee SH, So PT, Dong CY. Teng SW, et al. Invest Ophthalmol Vis Sci. 2006 Mar;47(3):1216-24. doi: 10.1167/iovs.04-1520. Invest Ophthalmol Vis Sci. 2006. PMID: 16505061
A water-immersion objective was used for convenient imaging of the curved surface of the eye. RESULTS: Multiphoton autofluorescence was useful in identifying cellular structures of the different domains of the ocular surface, and the SHG signal can be used to resolv …
A water-immersion objective was used for convenient imaging of the curved surface of the eye. RESULTS: Multiphoton autofluores …
Second-harmonic imaging microscopy of normal human and keratoconus cornea.
Morishige N, Wahlert AJ, Kenney MC, Brown DJ, Kawamoto K, Chikama T, Nishida T, Jester JV. Morishige N, et al. Invest Ophthalmol Vis Sci. 2007 Mar;48(3):1087-94. doi: 10.1167/iovs.06-1177. Invest Ophthalmol Vis Sci. 2007. PMID: 17325150 Free PMC article.
METHODS: Six normal corneas from eye bank donors and 13 corneas of patients with keratoconus, obtained after penetrating keratoplasty were examined. ...CONCLUSIONS: Compared with normal adult corneas, marked abnormalities were detected in the organizat …
METHODS: Six normal corneas from eye bank donors and 13 corneas of patients with keratoconus, obtained after penetratin …
Multiphoton fluorescence and second harmonic generation microscopy for imaging infectious keratitis.
Tan HY, Sun Y, Lo W, Teng SW, Wu RJ, Jee SH, Lin WC, Hsiao CH, Lin HC, Chen YF, Ma DH, Huang SC, Lin SJ, Dong CY. Tan HY, et al. J Biomed Opt. 2007 Mar-Apr;12(2):024013. doi: 10.1117/1.2717133. J Biomed Opt. 2007. PMID: 17477728 Free article.
The purpose of this study is to demonstrate the application of multiphoton fluorescence and second harmonic generation (SHG) microscopy for the ex-vivo visualization of human corneal morphological alterations due to infectious processes. ...With additional developme …
The purpose of this study is to demonstrate the application of multiphoton fluorescence and second harmonic generation (SHG) micro …
54 results