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Results: 1 to 20 of 72

1.

Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity.

Willmann KL, Klaver S, Doğu F, Santos-Valente E, Garncarz W, Bilic I, Mace E, Salzer E, Conde CD, Sic H, Májek P, Banerjee PP, Vladimer GI, Haskoloğlu S, Bolkent MG, Küpesiz A, Condino-Neto A, Colinge J, Superti-Furga G, Pickl WF, van Zelm MC, Eibel H, Orange JS, Ikincioğulları A, Boztuğ K.

Nat Commun. 2014 Nov 19;5:5360. doi: 10.1038/ncomms6360.

PMID:
25406581
[PubMed - in process]
Free PMC Article
2.

NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation.

Licciardello MP, Müllner MK, Dürnberger G, Kerzendorfer C, Boidol B, Trefzer C, Sdelci S, Berg T, Penz T, Schuster M, Bock C, Kralovics R, Superti-Furga G, Colinge J, Nijman SM, Kubicek S.

Oncogene. 2014 Sep 29. doi: 10.1038/onc.2014.319. [Epub ahead of print]

PMID:
25263445
[PubMed - as supplied by publisher]
3.

Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics.

Gridling M, Ficarro SB, Breitwieser FP, Song L, Parapatics K, Colinge J, Haura EB, Marto JA, Superti-Furga G, Bennett KL, Rix U.

Mol Cancer Ther. 2014 Nov;13(11):2751-62. doi: 10.1158/1535-7163.MCT-14-0152. Epub 2014 Sep 4.

PMID:
25189542
[PubMed - in process]
4.

The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia.

Sharif O, Gawish R, Warszawska JM, Martins R, Lakovits K, Hladik A, Doninger B, Brunner J, Korosec A, Schwarzenbacher RE, Berg T, Kralovics R, Colinge J, Mesteri I, Gilfillan S, Salmaggi A, Verschoor A, Colonna M, Knapp S.

PLoS Pathog. 2014 Jun 12;10(6):e1004167. doi: 10.1371/journal.ppat.1004167. eCollection 2014 Jun.

PMID:
24945405
[PubMed - in process]
Free PMC Article
5.

Comprehensive comparative and semiquantitative proteome of a very low number of native and matched epstein-barr-virus-transformed B lymphocytes infiltrating human melanoma.

Maurer M, Müller AC, Parapatics K, Pickl WF, Wagner C, Rudashevskaya EL, Breitwieser FP, Colinge J, Garg K, Griss J, Bennett KL, Wagner SN.

J Proteome Res. 2014 Jun 6;13(6):2830-45. doi: 10.1021/pr401270y. Epub 2014 May 6.

PMID:
24803318
[PubMed - indexed for MEDLINE]
6.

Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL-21 deficiency.

Salzer E, Kansu A, Sic H, Májek P, Ikincioğullari A, Dogu FE, Prengemann NK, Santos-Valente E, Pickl WF, Bilic I, Ban SA, Kuloğlu Z, Demir AM, Ensari A, Colinge J, Rizzi M, Eibel H, Boztug K.

J Allergy Clin Immunol. 2014 Jun;133(6):1651-9.e12. doi: 10.1016/j.jaci.2014.02.034. Epub 2014 Apr 17.

PMID:
24746753
[PubMed - indexed for MEDLINE]
7.

TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens.

Muellner MK, Duernberger G, Ganglberger F, Kerzendorfer C, Uras IZ, Schoenegger A, Bagienski K, Colinge J, Nijman SM.

BMC Bioinformatics. 2014 Apr 8;15:98. doi: 10.1186/1471-2105-15-98.

PMID:
24712852
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Building and exploring an integrated human kinase network: global organization and medical entry points.

Colinge J, César-Razquin A, Huber K, Breitwieser FP, Májek P, Superti-Furga G.

J Proteomics. 2014 Jul 31;107:113-27. doi: 10.1016/j.jprot.2014.03.028. Epub 2014 Apr 3.

PMID:
24704859
[PubMed - in process]
Free PMC Article
9.

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.

Huber KV, Salah E, Radic B, Gridling M, Elkins JM, Stukalov A, Jemth AS, Göktürk C, Sanjiv K, Strömberg K, Pham T, Berglund UW, Colinge J, Bennett KL, Loizou JI, Helleday T, Knapp S, Superti-Furga G.

Nature. 2014 Apr 10;508(7495):222-7. doi: 10.1038/nature13194. Epub 2014 Apr 2.

PMID:
24695225
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.

Boucheron N, Tschismarov R, Göeschl L, Moser MA, Lagger S, Sakaguchi S, Winter M, Lenz F, Vitko D, Breitwieser FP, Müller L, Hassan H, Bennett KL, Colinge J, Schreiner W, Egawa T, Taniuchi I, Matthias P, Seiser C, Ellmeier W.

Nat Immunol. 2014 May;15(5):439-48. doi: 10.1038/ni.2864. Epub 2014 Mar 30. Erratum in: Nat Immunol. 2014 Sep;15(9):894. Goeschl, Lisa [corrected to Göeschl, Lisa].

PMID:
24681565
[PubMed - indexed for MEDLINE]
11.

Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH.

Kainulainen M, Habjan M, Hubel P, Busch L, Lau S, Colinge J, Superti-Furga G, Pichlmair A, Weber F.

J Virol. 2014 Mar;88(6):3464-73. doi: 10.1128/JVI.02914-13. Epub 2014 Jan 8.

PMID:
24403578
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Interactome of two diverse RNA granules links mRNA localization to translational repression in neurons.

Fritzsche R, Karra D, Bennett KL, Ang FY, Heraud-Farlow JE, Tolino M, Doyle M, Bauer KE, Thomas S, Planyavsky M, Arn E, Bakosova A, Jungwirth K, Hörmann A, Palfi Z, Sandholzer J, Schwarz M, Macchi P, Colinge J, Superti-Furga G, Kiebler MA.

Cell Rep. 2013 Dec 26;5(6):1749-62. doi: 10.1016/j.celrep.2013.11.023. Epub 2013 Dec 19.

PMID:
24360960
[PubMed - indexed for MEDLINE]
Free Article
13.

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.

Li J, Bennett K, Stukalov A, Fang B, Zhang G, Yoshida T, Okamoto I, Kim JY, Song L, Bai Y, Qian X, Rawal B, Schell M, Grebien F, Winter G, Rix U, Eschrich S, Colinge J, Koomen J, Superti-Furga G, Haura EB.

Mol Syst Biol. 2013 Nov 5;9:705. doi: 10.1038/msb.2013.61.

PMID:
24189400
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A reversible gene trap collection empowers haploid genetics in human cells.

Bürckstümmer T, Banning C, Hainzl P, Schobesberger R, Kerzendorfer C, Pauler FM, Chen D, Them N, Schischlik F, Rebsamen M, Smida M, Fece de la Cruz F, Lapao A, Liszt M, Eizinger B, Guenzl PM, Blomen VA, Konopka T, Gapp B, Parapatics K, Maier B, Stöckl J, Fischl W, Salic S, Taba Casari MR, Knapp S, Bennett KL, Bock C, Colinge J, Kralovics R, Ammerer G, Casari G, Brummelkamp TR, Superti-Furga G, Nijman SM.

Nat Methods. 2013 Oct;10(10):965-71. doi: 10.1038/nmeth.2609. Epub 2013 Aug 25.

PMID:
24161985
[PubMed - indexed for MEDLINE]
15.

A target-disease network model of second-generation BCR-ABL inhibitor action in Ph+ ALL.

Rix U, Colinge J, Blatt K, Gridling M, Remsing Rix LL, Parapatics K, Cerny-Reiterer S, Burkard TR, Jäger U, Melo JV, Bennett KL, Valent P, Superti-Furga G.

PLoS One. 2013 Oct 10;8(10):e77155. doi: 10.1371/journal.pone.0077155. eCollection 2013.

PMID:
24130846
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Systems Biology Analysis of Kinase Inhibitor Action in Leukemia Treatments.

Colinge J.

Biomed Tech (Berl). 2013 Sep 7. pii: /j/bmte.2013.58.issue-s1-M/bmt-2013-4306/bmt-2013-4306.xml. doi: 10.1515/bmt-2013-4306. [Epub ahead of print] No abstract available.

PMID:
24042955
[PubMed - as supplied by publisher]
17.

Affinity purification strategies for proteomic analysis of transcription factor complexes.

Giambruno R, Grebien F, Stukalov A, Knoll C, Planyavsky M, Rudashevskaya EL, Colinge J, Superti-Furga G, Bennett KL.

J Proteome Res. 2013 Sep 6;12(9):4018-27. doi: 10.1021/pr4003323. Epub 2013 Aug 22.

PMID:
23937658
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The CRAPome: a contaminant repository for affinity purification-mass spectrometry data.

Mellacheruvu D, Wright Z, Couzens AL, Lambert JP, St-Denis NA, Li T, Miteva YV, Hauri S, Sardiu ME, Low TY, Halim VA, Bagshaw RD, Hubner NC, Al-Hakim A, Bouchard A, Faubert D, Fermin D, Dunham WH, Goudreault M, Lin ZY, Badillo BG, Pawson T, Durocher D, Coulombe B, Aebersold R, Superti-Furga G, Colinge J, Heck AJ, Choi H, Gstaiger M, Mohammed S, Cristea IM, Bennett KL, Washburn MP, Raught B, Ewing RM, Gingras AC, Nesvizhskii AI.

Nat Methods. 2013 Aug;10(8):730-6. doi: 10.1038/nmeth.2557. Epub 2013 Jul 7.

PMID:
23921808
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Experimental characterization of the human non-sequence-specific nucleic acid interactome.

Dürnberger G, Bürckstümmer T, Huber K, Giambruno R, Doerks T, Karayel E, Burkard TR, Kaupe I, Müller AC, Schönegger A, Ecker GF, Lohninger H, Bork P, Bennett KL, Superti-Furga G, Colinge J.

Genome Biol. 2013 Jul 31;14(7):R81. doi: 10.1186/gb-2013-14-7-r81.

PMID:
23902751
[PubMed - in process]
Free PMC Article
20.

A miniaturized chemical proteomic approach for target profiling of clinical kinase inhibitors in tumor biopsies.

Chamrád I, Rix U, Stukalov A, Gridling M, Parapatics K, Müller AC, Altiok S, Colinge J, Superti-Furga G, Haura EB, Bennett KL.

J Proteome Res. 2013 Sep 6;12(9):4005-17. doi: 10.1021/pr400309p. Epub 2013 Aug 20.

PMID:
23901793
[PubMed - indexed for MEDLINE]
Free PMC Article

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