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Items: 1 to 20 of 240

1.

Crystal structure of the human sterol transporter ABCG5/ABCG8.

Lee JY, Kinch LN, Borek DM, Wang J, Wang J, Urbatsch IL, Xie XS, Grishin NV, Cohen JC, Otwinowski Z, Hobbs HH, Rosenbaum DM.

Nature. 2016 May 4;533(7604):561-4. doi: 10.1038/nature17666.

PMID:
27144356
2.

Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins.

Smagris E, Gilyard S, BasuRay S, Cohen JC, Hobbs HH.

J Biol Chem. 2016 May 13;291(20):10659-76. doi: 10.1074/jbc.M116.719955. Epub 2016 Mar 24.

3.

Adult-onset liver disease and hepatocellular carcinoma in S-adenosylhomocysteine hydrolase deficiency.

Stender S, Chakrabarti RS, Xing C, Gotway G, Cohen JC, Hobbs HH.

Mol Genet Metab. 2015 Dec;116(4):269-74. doi: 10.1016/j.ymgme.2015.10.009. Epub 2015 Oct 26.

4.

Hepatic ANGPTL3 regulates adipose tissue energy homeostasis.

Wang Y, McNutt MC, Banfi S, Levin MG, Holland WL, Gusarova V, Gromada J, Cohen JC, Hobbs HH.

Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11630-5. doi: 10.1073/pnas.1515374112. Epub 2015 Aug 24.

5.

Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways.

Mitsche MA, McDonald JG, Hobbs HH, Cohen JC.

Elife. 2015 Jun 26;4:e07999. doi: 10.7554/eLife.07999.

6.

Reply.

Smagris E, BasuRay S, Gromada J, Cohen JC, Hobbs HH.

Hepatology. 2016 Feb;63(2):677. doi: 10.1002/hep.27945. Epub 2015 Aug 21. No abstract available.

PMID:
26099489
7.

ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys.

Gusarova V, Alexa CA, Wang Y, Rafique A, Kim JH, Buckler D, Mintah IJ, Shihanian LM, Cohen JC, Hobbs HH, Xin Y, Valenzuela DM, Murphy AJ, Yancopoulos GD, Gromada J.

J Lipid Res. 2015 Jul;56(7):1308-17. doi: 10.1194/jlr.M054890. Epub 2015 May 11.

PMID:
25964512
8.

Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion.

Wang Y, Gusarova V, Banfi S, Gromada J, Cohen JC, Hobbs HH.

J Lipid Res. 2015 Jul;56(7):1296-307. doi: 10.1194/jlr.M054882. Epub 2015 May 7.

PMID:
25954050
9.

Use of continuous positive airway pressure after rhinoplasty, septoplasty, and sinus surgery: A survey of current practice patterns.

Cohen JC, Larrabee YC, Weinstein AL, Stewart MG.

Laryngoscope. 2015 Nov;125(11):2612-6. doi: 10.1002/lary.25336. Epub 2015 May 6.

PMID:
25946236
10.

ANGPTL8/betatrophin does not control pancreatic beta cell expansion.

Gusarova V, Alexa CA, Na E, Stevis PE, Xin Y, Bonner-Weir S, Cohen JC, Hobbs HH, Murphy AJ, Yancopoulos GD, Gromada J.

Cell. 2014 Oct 23;159(3):691-6. doi: 10.1016/j.cell.2014.09.027.

11.

Relative roles of ABCG5/ABCG8 in liver and intestine.

Wang J, Mitsche MA, Lütjohann D, Cohen JC, Xie XS, Hobbs HH.

J Lipid Res. 2015 Feb;56(2):319-30. doi: 10.1194/jlr.M054544. Epub 2014 Nov 6.

12.

The Hemi-dissected Jack.

Cohen JC.

JAMA Facial Plast Surg. 2014 Sep-Oct;16(5):305. doi: 10.1001/jamafacial.2013.2375. No abstract available.

PMID:
25233295
13.

APOC3, coronary disease, and complexities of Mendelian randomization.

Cohen JC, Stender S, Hobbs HH.

Cell Metab. 2014 Sep 2;20(3):387-9. doi: 10.1016/j.cmet.2014.08.007.

14.

Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis.

Smagris E, BasuRay S, Li J, Huang Y, Lai KM, Gromada J, Cohen JC, Hobbs HH.

Hepatology. 2015 Jan;61(1):108-18. doi: 10.1002/hep.27242. Epub 2014 Oct 1.

15.

Safety of concurrent nasal and oropharyngeal surgery for obstructive sleep apnea.

Banuchi V, Cohen JC, Kacker A.

Ann Otol Rhinol Laryngol. 2014 Sep;123(9):619-22. doi: 10.1177/0003489414525587. Epub 2014 Mar 14.

PMID:
24634156
16.

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease.

Kozlitina J, Smagris E, Stender S, Nordestgaard BG, Zhou HH, Tybjærg-Hansen A, Vogt TF, Hobbs HH, Cohen JC.

Nat Genet. 2014 Apr;46(4):352-6. doi: 10.1038/ng.2901. Epub 2014 Feb 16.

17.

Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis.

Wang Y, Quagliarini F, Gusarova V, Gromada J, Valenzuela DM, Cohen JC, Hobbs HH.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16109-14. doi: 10.1073/pnas.1315292110. Epub 2013 Sep 16.

18.

Severe systemic reaction from calcium hydroxylapatite vocal fold filler.

Cohen JC, Reisacher W, Malone M, Sulica L.

Laryngoscope. 2013 Sep;123(9):2237-9. doi: 10.1002/lary.23762. Epub 2013 Jul 2. Review.

PMID:
23821534
19.

Laryngeal fracture after coughing.

Fenig M, Strasberg S, Cohen JC, Almadi R, Gold M.

Am J Emerg Med. 2013 Sep;31(9):1421.e1-3. doi: 10.1016/j.ajem.2013.05.013. Epub 2013 Jun 25.

PMID:
23806730
20.

Genetics. Simple genetics for a complex disease.

Cohen JC, Hobbs HH.

Science. 2013 May 10;340(6133):689-90. doi: 10.1126/science.1239101. No abstract available.

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