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Results: 1 to 20 of 115


KRAS-dependent sorting of miRNA to exosomes.

Cha DJ, Franklin JL, Dou Y, Liu Q, Higginbotham JN, Demory Beckler M, Weaver AM, Vickers K, Prasad N, Levy S, Zhang B, Coffey RJ, Patton JG.

Elife. 2015 Jul 1;4. doi: 10.7554/eLife.07197.


Linking patient outcome to high throughput protein expression data identifies novel regulators of colorectal adenocarcinoma aggressiveness.

French CL, Ye F, Revetta F, Zhang B, Coffey RJ, Washington MK, Deane NG, Beauchamp RD, Weaver AM.

F1000Res. 2015 Apr 24;4:99. doi: 10.12688/f1000research.6388.1. eCollection 2015.


3'-Deoxy-3'-[18F]-Fluorothymidine PET imaging reflects PI3K-mTOR-mediated pro-survival response to targeted therapy in colorectal cancer.

McKinley ET, Zhao P, Coffey RJ, Washington MK, Manning HC.

PLoS One. 2014 Sep 23;9(9):e108193. doi: 10.1371/journal.pone.0108193. eCollection 2014.


Proteogenomic characterization of human colon and rectal cancer.

Zhang B, Wang J, Wang X, Zhu J, Liu Q, Shi Z, Chambers MC, Zimmerman LJ, Shaddox KF, Kim S, Davies SR, Wang S, Wang P, Kinsinger CR, Rivers RC, Rodriguez H, Townsend RR, Ellis MJ, Carr SA, Tabb DL, Coffey RJ, Slebos RJ, Liebler DC; NCI CPTAC.

Nature. 2014 Sep 18;513(7518):382-7. doi: 10.1038/nature13438. Epub 2014 Jul 20.


DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia.

Markham NO, Doll CA, Dohn MR, Miller RK, Yu H, Coffey RJ, McCrea PD, Gamse JT, Reynolds AB.

Mol Biol Cell. 2014 Sep 1;25(17):2592-603. doi: 10.1091/mbc.E13-08-0492. Epub 2014 Jul 9.


Clinical accuracy and safety using the SynchroMed II intrathecal drug infusion pump.

Wesemann K, Coffey RJ, Wallace MS, Tan Y, Broste S, Buvanendran A.

Reg Anesth Pain Med. 2014 Jul-Aug;39(4):341-6. doi: 10.1097/AAP.0000000000000107.


Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.

Powell AE, Vlacich G, Zhao ZY, McKinley ET, Washington MK, Manning HC, Coffey RJ.

Am J Physiol Gastrointest Liver Physiol. 2014 Jul 1;307(1):G16-23. doi: 10.1152/ajpgi.00358.2013. Epub 2014 May 15.


Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans.

Kawasaki K, Freimuth J, Meyer DS, Lee MM, Tochimoto-Okamoto A, Benzinou M, Clermont FF, Wu G, Roy R, Letteboer TG, Ploos van Amstel JK, Giraud S, Dupuis-Girod S, Lesca G, Westermann CJ, Coffey RJ Jr, Akhurst RJ.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7723-8. doi: 10.1073/pnas.1318761111. Epub 2014 May 8.


Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer.

Li C, Ma H, Wang Y, Cao Z, Graves-Deal R, Powell AE, Starchenko A, Ayers GD, Washington MK, Kamath V, Desai K, Gerdes MJ, Solnica-Krezel L, Coffey RJ.

J Clin Invest. 2014 May;124(5):2172-87. Epub 2014 Apr 1.


From wavy hair to naked proteins: the role of transforming growth factor alpha in health and disease.

Singh B, Coffey RJ.

Semin Cell Dev Biol. 2014 Apr;28:12-21. doi: 10.1016/j.semcdb.2014.03.003. Epub 2014 Mar 12. Review.


A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells.

Hight MR, Cheung YY, Nickels ML, Dawson ES, Zhao P, Saleh S, Buck JR, Tang D, Washington MK, Coffey RJ, Manning HC.

Clin Cancer Res. 2014 Apr 15;20(8):2126-35. doi: 10.1158/1078-0432.CCR-13-2444. Epub 2014 Feb 26.


NEDD4L is downregulated in colorectal cancer and inhibits canonical WNT signaling.

Tanksley JP, Chen X, Coffey RJ.

PLoS One. 2013 Nov 28;8(11):e81514. doi: 10.1371/journal.pone.0081514. eCollection 2013.


Global phosphotyrosine proteomics identifies PKCδ as a marker of responsiveness to Src inhibition in colorectal cancer.

McKinley ET, Liu H, McDonald WH, Luo W, Zhao P, Coffey RJ, Hanks SK, Manning HC.

PLoS One. 2013 Nov 8;8(11):e80207. doi: 10.1371/journal.pone.0080207. eCollection 2013.


Deciphering genomic alterations in colorectal cancer through transcriptional subtype-based network analysis.

Zhu J, Wang J, Shi Z, Franklin JL, Deane NG, Coffey RJ, Beauchamp RD, Zhang B.

PLoS One. 2013 Nov 15;8(11):e79282. doi: 10.1371/journal.pone.0079282. eCollection 2013.


Trafficking of epidermal growth factor receptor ligands in polarized epithelial cells.

Singh B, Coffey RJ.

Annu Rev Physiol. 2014;76:275-300. doi: 10.1146/annurev-physiol-021113-170406. Epub 2013 Nov 8. Review.


Malignant transformation of colonic epithelial cells by a colon-derived long noncoding RNA.

Franklin JL, Rankin CR, Levy S, Snoddy JR, Zhang B, Washington MK, Thomson JM, Whitehead RH, Coffey RJ.

Biochem Biophys Res Commun. 2013 Oct 11;440(1):99-104. doi: 10.1016/j.bbrc.2013.09.040. Epub 2013 Sep 14.


Transformation of polarized epithelial cells by apical mistrafficking of epiregulin.

Singh B, Bogatcheva G, Washington MK, Coffey RJ.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):8960-5. doi: 10.1073/pnas.1305508110. Epub 2013 May 13.


Extracellular vesicles: communication, coercion, and conditioning.

Shifrin DA Jr, Demory Beckler M, Coffey RJ, Tyska MJ.

Mol Biol Cell. 2013 May;24(9):1253-9. doi: 10.1091/mbc.E12-08-0572.


LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor.

Wang Y, Poulin EJ, Coffey RJ.

Br J Cancer. 2013 May 14;108(9):1765-70. doi: 10.1038/bjc.2013.138. Epub 2013 Apr 4. Review.


Limits of [18F]-FLT PET as a biomarker of proliferation in oncology.

McKinley ET, Ayers GD, Smith RA, Saleh SA, Zhao P, Washington MK, Coffey RJ, Manning HC.

PLoS One. 2013;8(3):e58938. doi: 10.1371/journal.pone.0058938. Epub 2013 Mar 15.

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