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Results: 1 to 20 of 397


[18F]-FLT PET to predict early response to neoadjuvant therapy in KRAS wild-type rectal cancer: a pilot study.

McKinley ET, Watchmaker JM, Bapsi Chakravarthy A, Meyerhardt JA, Engelman JA, Walker RC, Kay Washington M, Coffey RJ, Charles Manning H.

Ann Nucl Med. 2015 Apr 22. [Epub ahead of print]


Loss of lrig1 leads to expansion of brunner glands followed by duodenal adenomas with gastric metaplasia.

Wang Y, Shi C, Lu Y, Poulin EJ, Franklin JL, Coffey RJ.

Am J Pathol. 2015 Apr;185(4):1123-34. doi: 10.1016/j.ajpath.2014.12.014.


Using a new Lrig1 reporter mouse to assess differences between two Lrig1 antibodies in the intestine.

Poulin EJ, Powell AE, Wang Y, Li Y, Franklin JL, Coffey RJ.

Stem Cell Res. 2014 Nov;13(3 Pt A):422-30. doi: 10.1016/j.scr.2014.09.002. Epub 2014 Sep 20.


3'-Deoxy-3'-[18F]-Fluorothymidine PET imaging reflects PI3K-mTOR-mediated pro-survival response to targeted therapy in colorectal cancer.

McKinley ET, Zhao P, Coffey RJ, Washington MK, Manning HC.

PLoS One. 2014 Sep 23;9(9):e108193. doi: 10.1371/journal.pone.0108193. eCollection 2014.


Proteogenomic characterization of human colon and rectal cancer.

Zhang B, Wang J, Wang X, Zhu J, Liu Q, Shi Z, Chambers MC, Zimmerman LJ, Shaddox KF, Kim S, Davies SR, Wang S, Wang P, Kinsinger CR, Rivers RC, Rodriguez H, Townsend RR, Ellis MJ, Carr SA, Tabb DL, Coffey RJ, Slebos RJ, Liebler DC; NCI CPTAC.

Nature. 2014 Sep 18;513(7518):382-7. doi: 10.1038/nature13438. Epub 2014 Jul 20.


DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia.

Markham NO, Doll CA, Dohn MR, Miller RK, Yu H, Coffey RJ, McCrea PD, Gamse JT, Reynolds AB.

Mol Biol Cell. 2014 Sep 1;25(17):2592-603. doi: 10.1091/mbc.E13-08-0492. Epub 2014 Jul 9.


Clinical accuracy and safety using the SynchroMed II intrathecal drug infusion pump.

Wesemann K, Coffey RJ, Wallace MS, Tan Y, Broste S, Buvanendran A.

Reg Anesth Pain Med. 2014 Jul-Aug;39(4):341-6. doi: 10.1097/AAP.0000000000000107.


Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.

Powell AE, Vlacich G, Zhao ZY, McKinley ET, Washington MK, Manning HC, Coffey RJ.

Am J Physiol Gastrointest Liver Physiol. 2014 Jul 1;307(1):G16-23. doi: 10.1152/ajpgi.00358.2013. Epub 2014 May 15.


Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans.

Kawasaki K, Freimuth J, Meyer DS, Lee MM, Tochimoto-Okamoto A, Benzinou M, Clermont FF, Wu G, Roy R, Letteboer TG, Ploos van Amstel JK, Giraud S, Dupuis-Girod S, Lesca G, Westermann CJ, Coffey RJ Jr, Akhurst RJ.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7723-8. doi: 10.1073/pnas.1318761111. Epub 2014 May 8.


Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer.

Li C, Ma H, Wang Y, Cao Z, Graves-Deal R, Powell AE, Starchenko A, Ayers GD, Washington MK, Kamath V, Desai K, Gerdes MJ, Solnica-Krezel L, Coffey RJ.

J Clin Invest. 2014 May;124(5):2172-87. Epub 2014 Apr 1.


From wavy hair to naked proteins: the role of transforming growth factor alpha in health and disease.

Singh B, Coffey RJ.

Semin Cell Dev Biol. 2014 Apr;28:12-21. doi: 10.1016/j.semcdb.2014.03.003. Epub 2014 Mar 12. Review.


A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells.

Hight MR, Cheung YY, Nickels ML, Dawson ES, Zhao P, Saleh S, Buck JR, Tang D, Washington MK, Coffey RJ, Manning HC.

Clin Cancer Res. 2014 Apr 15;20(8):2126-35. doi: 10.1158/1078-0432.CCR-13-2444. Epub 2014 Feb 26.


NEDD4L is downregulated in colorectal cancer and inhibits canonical WNT signaling.

Tanksley JP, Chen X, Coffey RJ.

PLoS One. 2013 Nov 28;8(11):e81514. doi: 10.1371/journal.pone.0081514. eCollection 2013.


Global phosphotyrosine proteomics identifies PKCδ as a marker of responsiveness to Src inhibition in colorectal cancer.

McKinley ET, Liu H, McDonald WH, Luo W, Zhao P, Coffey RJ, Hanks SK, Manning HC.

PLoS One. 2013 Nov 8;8(11):e80207. doi: 10.1371/journal.pone.0080207. eCollection 2013.


Deciphering genomic alterations in colorectal cancer through transcriptional subtype-based network analysis.

Zhu J, Wang J, Shi Z, Franklin JL, Deane NG, Coffey RJ, Beauchamp RD, Zhang B.

PLoS One. 2013 Nov 15;8(11):e79282. doi: 10.1371/journal.pone.0079282. eCollection 2013.


Trafficking of epidermal growth factor receptor ligands in polarized epithelial cells.

Singh B, Coffey RJ.

Annu Rev Physiol. 2014;76:275-300. doi: 10.1146/annurev-physiol-021113-170406. Epub 2013 Nov 8. Review.


Magnetic resonance imaging conditionally safe neurostimulation leads: investigation of the maximum safe lead tip temperature.

Coffey RJ, Kalin R, Olsen JM.

Neurosurgery. 2014 Feb;74(2):215-24; discussion 224-5. doi: 10.1227/NEU.0000000000000242. Review.


Malignant transformation of colonic epithelial cells by a colon-derived long noncoding RNA.

Franklin JL, Rankin CR, Levy S, Snoddy JR, Zhang B, Washington MK, Thomson JM, Whitehead RH, Coffey RJ.

Biochem Biophys Res Commun. 2013 Oct 11;440(1):99-104. doi: 10.1016/j.bbrc.2013.09.040. Epub 2013 Sep 14.


Thalamic DBS and neuropathic pain.

Coffey RJ.

Neurosurg Focus. 2013 Sep;35(3):E8. doi: 10.3171/2013.7.FOCUS13275. No abstract available.


Intrathecal gabapentin to treat chronic intractable noncancer pain.

Rauck R, Coffey RJ, Schultz DM, Wallace MS, Webster LR, McCarville SE, Grigsby EJ, Page LM.

Anesthesiology. 2013 Sep;119(3):675-86. doi: 10.1097/ALN.0b013e3182a10fbf.

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