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Data for action: collection and use of local data to end tuberculosis.

Theron G, Jenkins HE, Cobelens F, Abubakar I, Khan AJ, Cohen T, Dowdy DW.

Lancet. 2015 Oct 23. pii: S0140-6736(15)00321-9. doi: 10.1016/S0140-6736(15)00321-9. [Epub ahead of print] Review.


The potential of a multiplex high-throughput molecular assay for early detection of first and second line tuberculosis drug resistance mutations to improve infection control and reduce costs: a decision analytical modeling study.

Van't Hoog AH, Bergval I, Tukvadze N, Sengstake S, Aspindzelashvili R, Anthony RM, Cobelens F.

BMC Infect Dis. 2015 Oct 26;15:473. doi: 10.1186/s12879-015-1205-4.


Challenges in detection and treatment of multidrug resistant tuberculosis patients in Vietnam.

Hoang TT, Nguyen NV, Dinh SN, Nguyen HB, Cobelens F, Thwaites G, Nguyen HT, Nguyen AT, Wright P, Wertheim HF.

BMC Public Health. 2015 Sep 29;15(1):980. doi: 10.1186/s12889-015-2338-5.


The Distribution of Fitness Costs of Resistance-Conferring Mutations Is a Key Determinant for the Future Burden of Drug-Resistant Tuberculosis: A Model-Based Analysis.

Knight GM, Colijn C, Shrestha S, Fofana M, Cobelens F, White RG, Dowdy DW, Cohen T.

Clin Infect Dis. 2015 Oct 15;61Suppl 3:S147-54. doi: 10.1093/cid/civ579.


The Second Zambian National Tuberculosis Drug Resistance survey - a comparison of conventional and molecular methods.

Kapata N, Mbulo G, Cobelens F, de Haas P, Schaap A, Mwamba P, Mwanza W, Muvwimi M, Muyoyeta M, Moyo M, Mulenga L, Grobusch MP, Godfrey-Faussett P, Ayles H.

Trop Med Int Health. 2015 Nov;20(11):1492-1500. doi: 10.1111/tmi.12581. Epub 2015 Aug 27.


High Genotypic Discordance of Concurrent Mycobacterium tuberculosis Isolates from Sputum and Blood of HIV-Infected Individuals.

Ssengooba W, Cobelens FG, Nakiyingi L, Mboowa G, Armstrong DT, Manabe YC, Joloba ML, de Jong BC.

PLoS One. 2015 Jul 15;10(7):e0132581. doi: 10.1371/journal.pone.0132581. eCollection 2015.


How Do the New Definitions for Multidrug-Resistant Tuberculosis Treatment Outcomes Really Perform?

Gebhard A, van den Hof S, Cobelens F.

Am J Respir Crit Care Med. 2015 Jul 1;192(1):117. doi: 10.1164/rccm.201503-0517LE. No abstract available.


Impact on Patients' Treatment Outcomes of XpertMTB/RIF Implementation for the Diagnosis of Tuberculosis: Follow-Up of a Stepped-Wedge Randomized Clinical Trial.

Trajman A, Durovni B, Saraceni V, Menezes A, Cordeiro-Santos M, Cobelens F, Van den Hof S.

PLoS One. 2015 Apr 27;10(4):e0123252. doi: 10.1371/journal.pone.0123252. eCollection 2015.


The predictive value of current haemoglobin levels for incident tuberculosis and/or mortality during long-term antiretroviral therapy in South Africa: a cohort study.

Kerkhoff AD, Wood R, Cobelens FG, Gupta-Wright A, Bekker LG, Lawn SD.

BMC Med. 2015 Apr 2;13:70. doi: 10.1186/s12916-015-0320-9.


Variation and risk factors of drug resistant tuberculosis in sub-Saharan Africa: a systematic review and meta-analysis.

Lukoye D, Ssengooba W, Musisi K, Kasule GW, Cobelens FG, Joloba M, Gomez GB.

BMC Public Health. 2015 Mar 25;15:291. doi: 10.1186/s12889-015-1614-8.


Triage tests: a new priority for tuberculosis diagnostics.

García-Basteiro AL, Cobelens F.

Lancet Respir Med. 2015 Mar;3(3):177-8. doi: 10.1016/S2213-2600(15)00061-2. Epub 2015 Mar 9. No abstract available.


Target product profile of a molecular drug-susceptibility test for use in microscopy centers.

Denkinger CM, Dolinger D, Schito M, Wells W, Cobelens F, Pai M, Zignol M, Cirillo DM, Alland D, Casenghi M, Gallarda J, Boehme CC, Perkins MD.

J Infect Dis. 2015 Apr 1;211 Suppl 2:S39-49. doi: 10.1093/infdis/jiu682. Review.


Drivers and trajectories of resistance to new first-line drug regimens for tuberculosis.

Shrestha S, Knight GM, Fofana M, Cohen T, White RG, Cobelens F, Dowdy DW.

Open Forum Infect Dis. 2014 Aug 30;1(2):ofu073. doi: 10.1093/ofid/ofu073. eCollection 2014 Sep.


Resolution of anaemia in a cohort of HIV-infected patients with a high prevalence and incidence of tuberculosis receiving antiretroviral therapy in South Africa.

Kerkhoff AD, Wood R, Cobelens FG, Gupta-Wright A, Bekker LG, Lawn SD.

BMC Infect Dis. 2014 Dec 21;14:3860. doi: 10.1186/s12879-014-0702-1.


The Mycobacterium tuberculosis Uganda II family and resistance to first-line anti-tuberculosis drugs in Uganda.

Ezati N, Lukoye D, Wampande EM, Musisi K, Kasule GW, Cobelens FG, Kateete DP, Joloba ML.

BMC Infect Dis. 2014 Dec 19;14:703. doi: 10.1186/s12879-014-0703-0.


Impact of replacing smear microscopy with Xpert MTB/RIF for diagnosing tuberculosis in Brazil: a stepped-wedge cluster-randomized trial.

Durovni B, Saraceni V, van den Hof S, Trajman A, Cordeiro-Santos M, Cavalcante S, Menezes A, Cobelens F.

PLoS Med. 2014 Dec 9;11(12):e1001766. doi: 10.1371/journal.pmed.1001766. eCollection 2014 Dec.


High tuberculosis burden among people living with HIV in southern Mozambique.

García-Basteiro AL, López-Varela E, Respeito D, González R, Naniche D, Manhiça I, Macete E, Cobelens F, Alonso PL.

Eur Respir J. 2015 Feb;45(2):547-9. doi: 10.1183/09031936.00145714. Epub 2014 Nov 13. No abstract available.


Clinical utility of a novel molecular assay in various combination strategies with existing methods for diagnosis of HIV-related tuberculosis in Uganda.

Ssengooba W, Nakiyingi L, Armstrong DT, Cobelens FG, Alland D, Manabe YC, Dorman SE, Ellner JJ, Joloba ML.

PLoS One. 2014 Sep 15;9(9):e107595. doi: 10.1371/journal.pone.0107595. eCollection 2014.


Impact and cost-effectiveness of current and future tuberculosis diagnostics: the contribution of modelling.

Dowdy DW, Houben R, Cohen T, Pai M, Cobelens F, Vassall A, Menzies NA, Gomez GB, Langley I, Squire SB, White R; TB MAC meeting participants.

Int J Tuberc Lung Dis. 2014 Sep;18(9):1012-8. doi: 10.5588/ijtld.13.0851.


High positive predictive value of Xpert in a low rifampicin resistance prevalence setting.

Trajman A, Durovni B, Saraceni V, Cordeiro-Santos M, Cobelens F, van den Hof S.

Eur Respir J. 2014 Dec;44(6):1711-3. doi: 10.1183/09031936.00115514. Epub 2014 Sep 3. No abstract available.

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