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Results: 1 to 20 of 233

1.

Influence of multidrug resistance and drug transport proteins on chemotherapy drug metabolism.

Joyce H, McCann A, Clynes M, Larkin A.

Expert Opin Drug Metab Toxicol. 2015 Apr 2:1-15. [Epub ahead of print]

PMID:
25836015
2.

Prolonged pre-incubation increases the susceptibility of Galleria mellonella larvae to bacterial and fungal infection.

Browne N, Surlis C, Maher A, Gallagher C, Carolan JC, Clynes M, Kavanagh K.

Virulence. 2015 Mar 18:0. [Epub ahead of print]

PMID:
25785635
3.

Predictive biomarkers for dasatinib treatment in melanoma.

Eustace AJ, Kennedy S, Larkin AM, Mahgoub T, Tryfonopoulos D, O'Driscoll L, Clynes M, Crown J, O'Donovan N.

Oncoscience. 2014 Mar 12;1(2):158-66. eCollection 2014.

4.

Glycosylation patterns of kidney proteins differ in rat diabetic nephropathy.

Ravidà A, Musante L, Kreivi M, Miinalainen I, Byrne B, Saraswat M, Henry M, Meleady P, Clynes M, Holthofer H.

Kidney Int. 2015 Jan 14. doi: 10.1038/ki.2014.387. [Epub ahead of print]

PMID:
25587705
5.

Elevated levels of 14-3-3 proteins, serotonin, gamma enolase and pyruvate kinase identified in clinical samples from patients diagnosed with colorectal cancer.

Dowling P, Hughes DJ, Larkin AM, Meiller J, Henry M, Meleady P, Lynch V, Pardini B, Naccarati A, Levy M, Vodicka P, Neary P, Clynes M.

Clin Chim Acta. 2015 Feb 20;441:133-41. doi: 10.1016/j.cca.2014.12.005. Epub 2014 Dec 23.

PMID:
25540887
6.

Conserved microRNA function as a basis for Chinese hamster ovary cell engineering.

Kelly PS, Gallagher C, Clynes M, Barron N.

Biotechnol Lett. 2015 Apr;37(4):787-98. doi: 10.1007/s10529-014-1751-7. Epub 2014 Dec 21.

PMID:
25527440
7.

Abnormal levels of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) in tumour tissue and blood samples from patients diagnosed with lung cancer.

Dowling P, Pollard D, Larkin A, Henry M, Meleady P, Gately K, O'Byrne K, Barr MP, Lynch V, Ballot J, Crown J, Moriarty M, O'Brien E, Morgan R, Clynes M.

Mol Biosyst. 2015 Mar;11(3):743-52. doi: 10.1039/c4mb00384e. Epub 2014 Dec 8.

PMID:
25483567
8.

Identification of proteins found to be significantly altered when comparing the serum proteome from Multiple Myeloma patients with varying degrees of bone disease.

Dowling P, Hayes C, Ting KR, Hameed A, Meiller J, Mitsiades C, Anderson KC, Clynes M, Clarke C, Richardson P, O'Gorman P.

BMC Genomics. 2014 Oct 17;15:904. doi: 10.1186/1471-2164-15-904.

9.

Exposure of a corneal epithelial cell line (hTCEpi) to Demodex-associated Bacillus proteins results in an inflammatory response.

McMahon FW, Gallagher C, O'Reilly N, Clynes M, O'Sullivan F, Kavanagh K.

Invest Ophthalmol Vis Sci. 2014 Oct 2;55(10):7019-28. doi: 10.1167/iovs.14-15018.

PMID:
25277231
10.

Bone disease in multiple myeloma: pathophysiology and management.

Hameed A, Brady JJ, Dowling P, Clynes M, O'Gorman P.

Cancer Growth Metastasis. 2014 Aug 10;7:33-42. doi: 10.4137/CGM.S16817. eCollection 2014. Review.

11.

Further evidence of the developmental origins of osteoarthritis: results from the Hertfordshire Cohort Study.

Clynes MA, Parsons C, Edwards MH, Jameson KA, Harvey NC, Sayer AA, Cooper C, Dennison EM.

J Dev Orig Health Dis. 2014 Dec;5(6):453-8. doi: 10.1017/S2040174414000373. Epub 2014 Aug 26.

PMID:
25154411
12.

Comparative transcriptomic analysis of cultivated limbal epithelium and donor corneal tissue reveals altered wound healing gene expression.

Gallagher C, Clarke C, Aherne ST, Katikireddy KR, Doolan P, Lynch V, Shaw S, Bobart-Hone A, Murphy C, Clynes M, Power W, O'Sullivan F.

Invest Ophthalmol Vis Sci. 2014 Aug 14;55(9):5795-805. doi: 10.1167/iovs.14-14664.

PMID:
25125605
13.

PP2A inhibition overcomes acquired resistance to HER2 targeted therapy.

McDermott MS, Browne BC, Conlon NT, O'Brien NA, Slamon DJ, Henry M, Meleady P, Clynes M, Dowling P, Crown J, O'Donovan N.

Mol Cancer. 2014 Jun 24;13:157. doi: 10.1186/1476-4598-13-157.

14.

A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy.

Pohl K, Hayes E, Keenan J, Henry M, Meleady P, Molloy K, Jundi B, Bergin DA, McCarthy C, McElvaney OJ, White MM, Clynes M, Reeves EP, McElvaney NG.

Blood. 2014 Aug 14;124(7):999-1009. doi: 10.1182/blood-2014-02-555268. Epub 2014 Jun 16.

15.

Identification and functional validation of RAD23B as a potential protein in human breast cancer progression.

Linge A, Maurya P, Friedrich K, Baretton GB, Kelly S, Henry M, Clynes M, Larkin A, Meleady P.

J Proteome Res. 2014 Jul 3;13(7):3212-22. doi: 10.1021/pr4012156. Epub 2014 Jun 19.

PMID:
24897598
16.

Intricate effects of primary motor neuronopathy on contractile proteins and metabolic muscle enzymes as revealed by label-free mass spectrometry.

Holland A, Schmitt-John T, Dowling P, Meleady P, Henry M, Clynes M, Ohlendieck K.

Biosci Rep. 2014 Jul 1;34(4). pii: e00119. doi: 10.1042/BSR20140029.

17.

7B7: a novel antibody directed against the Ku70/Ku80 heterodimer blocks invasion in pancreatic and lung cancer cells.

O'Sullivan D, Henry M, Joyce H, Walsh N, Mc Auley E, Dowling P, Swan N, Moriarty M, Barnham P, Clynes M, Larkin A.

Tumour Biol. 2014 Jul;35(7):6983-97. doi: 10.1007/s13277-014-1857-5. Epub 2014 Apr 18.

PMID:
24744142
18.

In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies.

McDermott M, Eustace AJ, Busschots S, Breen L, Crown J, Clynes M, O'Donovan N, Stordal B.

Front Oncol. 2014 Mar 6;4:40. doi: 10.3389/fonc.2014.00040. eCollection 2014.

19.

Cell culture models for study of differentiated adipose cells.

Clynes M.

Stem Cell Res Ther. 2014 Dec 16;5(6):137. doi: 10.1186/scrt527.

20.

Increased outer arm and core fucose residues on the N-glycans of mutated alpha-1 antitrypsin protein from alpha-1 antitrypsin deficient individuals.

McCarthy C, Saldova R, O'Brien ME, Bergin DA, Carroll TP, Keenan J, Meleady P, Henry M, Clynes M, Rudd PM, Reeves EP, McElvaney NG.

J Proteome Res. 2014 Feb 7;13(2):596-605. doi: 10.1021/pr400752t. Epub 2013 Dec 13.

PMID:
24328305
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