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Results: 1 to 20 of 225

1.

Identification of proteins found to be significantly altered when comparing the serum proteome from Multiple Myeloma patients with varying degrees of bone disease.

Dowling P, Hayes C, Ting KR, Hameed A, Meiller J, Mitsiades C, Anderson KC, Clynes M, Clarke C, Richardson P, O Gorman P.

BMC Genomics. 2014 Oct 17;15(1):904. [Epub ahead of print]

PMID:
25322877
[PubMed - as supplied by publisher]
Free Article
2.

Exposure of a corneal epithelial cell line (hTCEpi) to Demodex-associated Bacillus proteins results in an inflammatory response.

McMahon F, Gallagher C, O'Reilly N, Clynes M, O'Sullivan F, Kavanagh K.

Invest Ophthalmol Vis Sci. 2014 Oct 2. pii: IOVS-14-15018. doi: 10.1167/iovs.14-15018. [Epub ahead of print]

PMID:
25277231
[PubMed - as supplied by publisher]
3.

Bone disease in multiple myeloma: pathophysiology and management.

Hameed A, Brady JJ, Dowling P, Clynes M, O'Gorman P.

Cancer Growth Metastasis. 2014 Aug 10;7:33-42. doi: 10.4137/CGM.S16817. eCollection 2014. Review.

PMID:
25187738
[PubMed]
Free PMC Article
4.

Further evidence of the developmental origins of osteoarthritis: results from the Hertfordshire Cohort Study.

Clynes MA, Parsons C, Edwards MH, Jameson KA, Harvey NC, Aihie Sayer A, Cooper C, Dennison EM.

J Dev Orig Health Dis. 2014 Aug 26:1-6. [Epub ahead of print]

PMID:
25154411
[PubMed - as supplied by publisher]
5.

Comparative transcriptomic analysis of cultivated limbal epithelium and donor corneal tissue reveals altered wound healing gene expression.

Gallagher C, Clarke C, Aherne ST, Katikireddy KR, Doolan P, Lynch V, Shaw S, Bobart-Hone A, Murphy C, Clynes M, Power W, O'Sullivan F.

Invest Ophthalmol Vis Sci. 2014 Aug 14;55(9):5795-805. doi: 10.1167/iovs.14-14664.

PMID:
25125605
[PubMed - in process]
6.

PP2A inhibition overcomes acquired resistance to HER2 targeted therapy.

McDermott MS, Browne BC, Conlon NT, O'Brien NA, Slamon DJ, Henry M, Meleady P, Clynes M, Dowling P, Crown J, O'Donovan N.

Mol Cancer. 2014 Jun 24;13:157. doi: 10.1186/1476-4598-13-157.

PMID:
24958351
[PubMed - in process]
Free Article
7.

A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy.

Pohl K, Hayes E, Keenan J, Henry M, Meleady P, Molloy K, Jundi B, Bergin DA, McCarthy C, McElvaney OJ, White MM, Clynes M, Reeves EP, McElvaney NG.

Blood. 2014 Aug 14;124(7):999-1009. doi: 10.1182/blood-2014-02-555268. Epub 2014 Jun 16.

PMID:
24934256
[PubMed - in process]
Free PMC Article
8.

Identification and functional validation of RAD23B as a potential protein in human breast cancer progression.

Linge A, Maurya P, Friedrich K, Baretton GB, Kelly S, Henry M, Clynes M, Larkin A, Meleady P.

J Proteome Res. 2014 Jul 3;13(7):3212-22. doi: 10.1021/pr4012156. Epub 2014 Jun 19.

PMID:
24897598
[PubMed - in process]
9.

Intricate effects of primary motor neuronopathy on contractile proteins and metabolic muscle enzymes as revealed by label-free mass spectrometry.

Holland A, Schmitt-John T, Dowling P, Meleady P, Henry M, Clynes M, Ohlendieck K.

Biosci Rep. 2014 Jul 1;34(4). pii: e00119. doi: 10.1042/BSR20140029.

PMID:
24895011
[PubMed - in process]
Free PMC Article
10.

7B7: a novel antibody directed against the Ku70/Ku80 heterodimer blocks invasion in pancreatic and lung cancer cells.

O'Sullivan D, Henry M, Joyce H, Walsh N, Mc Auley E, Dowling P, Swan N, Moriarty M, Barnham P, Clynes M, Larkin A.

Tumour Biol. 2014 Jul;35(7):6983-97. doi: 10.1007/s13277-014-1857-5. Epub 2014 Apr 18.

PMID:
24744142
[PubMed - indexed for MEDLINE]
11.

In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies.

McDermott M, Eustace AJ, Busschots S, Breen L, Crown J, Clynes M, O'Donovan N, Stordal B.

Front Oncol. 2014 Mar 6;4:40. doi: 10.3389/fonc.2014.00040. eCollection 2014.

PMID:
24639951
[PubMed]
Free PMC Article
12.

Increased outer arm and core fucose residues on the N-glycans of mutated alpha-1 antitrypsin protein from alpha-1 antitrypsin deficient individuals.

McCarthy C, Saldova R, O'Brien ME, Bergin DA, Carroll TP, Keenan J, Meleady P, Henry M, Clynes M, Rudd PM, Reeves EP, McElvaney NG.

J Proteome Res. 2014 Feb 7;13(2):596-605. doi: 10.1021/pr400752t. Epub 2013 Dec 13.

PMID:
24328305
[PubMed - in process]
13.

CHO cell culture longevity and recombinant protein yield are enhanced by depletion of miR-7 activity via sponge decoy vectors.

Sanchez N, Kelly P, Gallagher C, Lao NT, Clarke C, Clynes M, Barron N.

Biotechnol J. 2014 Mar;9(3):396-404. doi: 10.1002/biot.201300325. Epub 2013 Dec 10.

PMID:
24166820
[PubMed - indexed for MEDLINE]
14.

Proteomics in uveal melanoma.

Ramasamy P, Murphy CC, Clynes M, Horgan N, Moriarty P, Tiernan D, Beatty S, Kennedy S, Meleady P.

Exp Eye Res. 2014 Jan;118:1-12. doi: 10.1016/j.exer.2013.09.005. Epub 2013 Sep 19. Review.

PMID:
24056206
[PubMed - indexed for MEDLINE]
15.

BreastMark: an integrated approach to mining publicly available transcriptomic datasets relating to breast cancer outcome.

Madden SF, Clarke C, Gaule P, Aherne ST, O'Donovan N, Clynes M, Crown J, Gallagher WM.

Breast Cancer Res. 2013;15(4):R52.

PMID:
23820017
[PubMed - in process]
Free PMC Article
16.

A gene expression profile indicative of early stage HER2 targeted therapy response.

O'Neill F, Madden SF, Clynes M, Crown J, Doolan P, Aherne ST, O'Connor R.

Mol Cancer. 2013 Jul 1;12:69. doi: 10.1186/1476-4598-12-69.

PMID:
23816254
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

MiR-7 triggers cell cycle arrest at the G1/S transition by targeting multiple genes including Skp2 and Psme3.

Sanchez N, Gallagher M, Lao N, Gallagher C, Clarke C, Doolan P, Aherne S, Blanco A, Meleady P, Clynes M, Barron N.

PLoS One. 2013 Jun 6;8(6):e65671. doi: 10.1371/journal.pone.0065671. Print 2013.

PMID:
23762407
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis.

Clarke C, Madden SF, Doolan P, Aherne ST, Joyce H, O'Driscoll L, Gallagher WM, Hennessy BT, Moriarty M, Crown J, Kennedy S, Clynes M.

Carcinogenesis. 2013 Oct;34(10):2300-8. doi: 10.1093/carcin/bgt208. Epub 2013 Jun 5.

PMID:
23740839
[PubMed - indexed for MEDLINE]
Free Article
19.

Proteomic profiling of cardiomyopathic tissue from the aged mdx model of Duchenne muscular dystrophy reveals a drastic decrease in laminin, nidogen and annexin.

Holland A, Dowling P, Zweyer M, Swandulla D, Henry M, Clynes M, Ohlendieck K.

Proteomics. 2013 Aug;13(15):2312-23. doi: 10.1002/pmic.201200578. Epub 2013 Jul 8.

PMID:
23713012
[PubMed - indexed for MEDLINE]
20.

Transcriptomic analysis of clonal growth rate variation during CHO cell line development.

Doolan P, Clarke C, Kinsella P, Breen L, Meleady P, Leonard M, Zhang L, Clynes M, Aherne ST, Barron N.

J Biotechnol. 2013 Jul 10;166(3):105-13. doi: 10.1016/j.jbiotec.2013.04.014. Epub 2013 May 4.

PMID:
23651948
[PubMed - indexed for MEDLINE]

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