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Results: 1 to 20 of 422

1.

Genome sequencing of normal cells reveals developmental lineages and mutational processes.

Behjati S, Huch M, van Boxtel R, Karthaus W, Wedge DC, Tamuri AU, Martincorena I, Petljak M, Alexandrov LB, Gundem G, Tarpey PS, Roerink S, Blokker J, Maddison M, Mudie L, Robinson B, Nik-Zainal S, Campbell P, Goldman N, van de Wetering M, Cuppen E, Clevers H, Stratton MR.

Nature. 2014 Jun 29. doi: 10.1038/nature13448. [Epub ahead of print]

PMID:
25043003
[PubMed - as supplied by publisher]
2.

Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-γ.

Farin HF, Karthaus WR, Kujala P, Rakhshandehroo M, Schwank G, Vries RG, Kalkhoven E, Nieuwenhuis EE, Clevers H.

J Exp Med. 2014 Jun 30;211(7):1393-405. doi: 10.1084/jem.20130753.

PMID:
24980747
[PubMed - in process]
3.

Leucine-rich Repeat-containing G-protein Coupled Receptor 5 Marks Short-term Hematopoietic Stem and Progenitor Cells during Mouse Embryonic Development.

Liu D, He XC, Qian P, Barker N, Trainor PA, Clevers H, Liu H, Li L.

J Biol Chem. 2014 Jun 25. pii: jbc.M114.568170. [Epub ahead of print]

PMID:
24966324
[PubMed - as supplied by publisher]
Free Article
4.

Paneth cells.

van Es JH, Clevers H.

Curr Biol. 2014 Jun 16;24(12):R547-8. doi: 10.1016/j.cub.2014.04.049.

PMID:
24937274
[PubMed - in process]
5.

Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells.

Forster R, Chiba K, Schaeffer L, Regalado SG, Lai CS, Gao Q, Kiani S, Farin HF, Clevers H, Cost GJ, Chan A, Rebar EJ, Urnov FD, Gregory PD, Pachter L, Jaenisch R, Hockemeyer D.

Stem Cell Reports. 2014 Jun 3;2(6):838-52. doi: 10.1016/j.stemcr.2014.05.001. eCollection 2014 Jun 3.

PMID:
24936470
[PubMed]
Free PMC Article
6.

Polarizing intestinal epithelial cells electrically through Ror2.

Cao L, McCaig CD, Scott RH, Zhao S, Milne G, Clevers H, Zhao M, Pu J.

J Cell Sci. 2014 Jun 13. pii: jcs.146357. [Epub ahead of print]

PMID:
24928904
[PubMed - as supplied by publisher]
Free Article
7.

Stem Cells Marked by the R-Spondin Receptor LGR5.

Koo BK, Clevers H.

Gastroenterology. 2014 Aug;147(2):289-302. doi: 10.1053/j.gastro.2014.05.007. Epub 2014 May 21. Review.

PMID:
24859206
[PubMed - as supplied by publisher]
8.

Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.

Wang K, Yuen ST, Xu J, Lee SP, Yan HH, Shi ST, Siu HC, Deng S, Chu KM, Law S, Chan KH, Chan AS, Tsui WY, Ho SL, Chan AK, Man JL, Foglizzo V, Ng MK, Chan AS, Ching YP, Cheng GH, Xie T, Fernandez J, Li VS, Clevers H, Rejto PA, Mao M, Leung SY.

Nat Genet. 2014 Jun;46(6):573-82. doi: 10.1038/ng.2983. Epub 2014 May 11.

PMID:
24816253
[PubMed - in process]
9.

Loss of syntaxin 3 causes variant microvillus inclusion disease.

Wiegerinck CL, Janecke AR, Schneeberger K, Vogel GF, van Haaften-Visser DY, Escher JC, Adam R, Thöni CE, Pfaller K, Jordan AJ, Weis CA, Nijman IJ, Monroe GR, van Hasselt PM, Cutz E, Klumperman J, Clevers H, Nieuwenhuis EE, Houwen RH, van Haaften G, Hess MW, Huber LA, Stapelbroek JM, Müller T, Middendorp S.

Gastroenterology. 2014 Jul;147(1):65-68.e10. doi: 10.1053/j.gastro.2014.04.002. Epub 2014 Apr 12.

PMID:
24726755
[PubMed - in process]
10.

Selection of personalized patient therapy through the use of knowledge-based computational models that identify tumor-driving signal transduction pathways.

Verhaegh W, van Ooijen H, Inda MA, Hatzis P, Versteeg R, Smid M, Martens J, Foekens J, van de Wiel P, Clevers H, van de Stolpe A.

Cancer Res. 2014 Jun 1;74(11):2936-45. doi: 10.1158/0008-5472.CAN-13-2515. Epub 2014 Apr 2.

PMID:
24695361
[PubMed - in process]
11.

Organoid cultures for the analysis of cancer phenotypes.

Sachs N, Clevers H.

Curr Opin Genet Dev. 2014 Feb;24:68-73. doi: 10.1016/j.gde.2013.11.012. Epub 2013 Dec 31.

PMID:
24657539
[PubMed - in process]
12.

KLF5 regulates the integrity and oncogenicity of intestinal stem cells.

Nakaya T, Ogawa S, Manabe I, Tanaka M, Sanada M, Sato T, Taketo MM, Nakao K, Clevers H, Fukayama M, Kuroda M, Nagai R.

Cancer Res. 2014 May 15;74(10):2882-91. doi: 10.1158/0008-5472.CAN-13-2574. Epub 2014 Mar 13.

PMID:
24626089
[PubMed - in process]
13.

STRAD pseudokinases regulate axogenesis and LKB1 stability.

Veleva-Rotse BO, Smart JL, Baas AF, Edmonds B, Zhao ZM, Brown A, Klug LR, Hansen K, Reilly G, Gardner AP, Subbiah K, Gaucher EA, Clevers H, Barnes AP.

Neural Dev. 2014 Mar 4;9:5. doi: 10.1186/1749-8104-9-5.

PMID:
24594058
[PubMed - in process]
Free PMC Article
14.

The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength.

de Lau W, Peng WC, Gros P, Clevers H.

Genes Dev. 2014 Feb 15;28(4):305-16. doi: 10.1101/gad.235473.113. Review.

PMID:
24532711
[PubMed - indexed for MEDLINE]
15.

Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging.

Ritsma L, Ellenbroek SI, Zomer A, Snippert HJ, de Sauvage FJ, Simons BD, Clevers H, van Rheenen J.

Nature. 2014 Mar 20;507(7492):362-5. doi: 10.1038/nature12972. Epub 2014 Feb 16.

PMID:
24531760
[PubMed - indexed for MEDLINE]
16.

Retroviral gene expression control in primary organoid cultures.

Koo BK, Sasselli V, Clevers H.

Curr Protoc Stem Cell Biol. 2013 Nov 13;27:Unit 5A.6.. doi: 10.1002/9780470151808.sc05a06s27.

PMID:
24510288
[PubMed - in process]
17.

Adult stem cells in the small intestine are intrinsically programmed with their location-specific function.

Middendorp S, Schneeberger K, Wiegerinck CL, Mokry M, Akkerman RD, van Wijngaarden S, Clevers H, Nieuwenhuis EE.

Stem Cells. 2014 May;32(5):1083-91. doi: 10.1002/stem.1655.

PMID:
24496776
[PubMed - in process]
18.

Ovarian LGR5 is critical for successful pregnancy.

Sun X, Terakawa J, Clevers H, Barker N, Daikoku T, Dey SK.

FASEB J. 2014 May;28(5):2380-9. doi: 10.1096/fj.13-248344. Epub 2014 Jan 27.

PMID:
24469993
[PubMed - indexed for MEDLINE]
19.

Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development.

Liu X, Chen X, Zhong B, Wang A, Wang X, Chu F, Nurieva RI, Yan X, Chen P, van der Flier LG, Nakatsukasa H, Neelapu SS, Chen W, Clevers H, Tian Q, Qi H, Wei L, Dong C.

Nature. 2014 Mar 27;507(7493):513-8. doi: 10.1038/nature12910. Epub 2014 Jan 19.

PMID:
24463518
[PubMed - indexed for MEDLINE]
20.

Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF.

Schuijers J, Mokry M, Hatzis P, Cuppen E, Clevers H.

EMBO J. 2014 Jan 13;33(2):146-56. doi: 10.1002/embj.201385358. Epub 2014 Jan 10.

PMID:
24413017
[PubMed - indexed for MEDLINE]
Free Article

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