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Results: 1 to 20 of 329


Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity.

Dalmas E, Toubal A, Alzaid F, Blazek K, Eames HL, Lebozec K, Pini M, Hainault I, Montastier E, Denis RG, Ancel P, Lacombe A, Ling Y, Allatif O, Cruciani-Guglielmacci C, André S, Viguerie N, Poitou C, Stich V, Torcivia A, Foufelle F, Luquet S, Aron-Wisnewsky J, Langin D, Clément K, Udalova IA, Venteclef N.

Nat Med. 2015 May 4. doi: 10.1038/nm.3829. [Epub ahead of print]


Bariatric Surgery Induces Disruption in Inflammatory Signaling Pathways Mediated by Immune Cells in Adipose Tissue: A RNA-Seq Study.

Poitou C, Perret C, Mathieu F, Truong V, Blum Y, Durand H, Alili R, Chelghoum N, Pelloux V, Aron-Wisnewsky J, Torcivia A, Bouillot JL, Parks BW, Ninio E, Clément K, Tiret L.

PLoS One. 2015 May 4;10(5):e0125718. doi: 10.1371/journal.pone.0125718. eCollection 2015.


Invasive urodynamic studies for the management of lower urinary tract symptoms (LUTS) in men with voiding dysfunction.

Clement KD, Burden H, Warren K, Lapitan MC, Omar MI, Drake MJ.

Cochrane Database Syst Rev. 2015 Apr 28;4:CD011179. doi: 10.1002/14651858.CD011179.pub2.


Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells.

Liao J, Karnik R, Gu H, Ziller MJ, Clement K, Tsankov AM, Akopian V, Gifford CA, Donaghey J, Galonska C, Pop R, Reyon D, Tsai SQ, Mallard W, Joung JK, Rinn JL, Gnirke A, Meissner A.

Nat Genet. 2015 May;47(5):469-78. doi: 10.1038/ng.3258. Epub 2015 Mar 30.


Profiling of the three circulating monocyte subpopulations in human obesity.

Devêvre EF, Renovato-Martins M, Clément K, Sautès-Fridman C, Cremer I, Poitou C.

J Immunol. 2015 Apr 15;194(8):3917-23. doi: 10.4049/jimmunol.1402655. Epub 2015 Mar 18.


The macrophage activation marker sCD163 is independently associated with NAFLD severity in morbid obesity and reduced by bariatric surgery.

Kazankov K, Tordjman J, Møller HJ, Vilstrup H, Poitou C, Bedossa P, Bouillot JL, Clement K, Grønbaek H.

J Gastroenterol Hepatol. 2015 Mar 13. doi: 10.1111/jgh.12943. [Epub ahead of print]


Seven Novel Deleterious LEPR Mutations Found in Early-Onset Obesity: a ΔExon6-8 Shared by Subjects From Reunion Island, France, Suggests a Founder Effect.

Huvenne H, Le Beyec J, Pépin D, Alili R, Kherchiche PP, Jeannic E, Frelut ML, Lacorte JM, Nicolino M, Viard A, Laville M, Ledoux S, Tounian P, Poitou C, Dubern B, Clément K.

J Clin Endocrinol Metab. 2015 May;100(5):E757-66. doi: 10.1210/jc.2015-1036. Epub 2015 Mar 9.


Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients.

Magalhaes I, Pingris K, Poitou C, Bessoles S, Venteclef N, Kiaf B, Beaudoin L, Da Silva J, Allatif O, Rossjohn J, Kjer-Nielsen L, McCluskey J, Ledoux S, Genser L, Torcivia A, Soudais C, Lantz O, Boitard C, Aron-Wisnewsky J, Larger E, Clément K, Lehuen A.

J Clin Invest. 2015 Apr;125(4):1752-62. doi: 10.1172/JCI78941. Epub 2015 Mar 9.


Human adipocytes induce inflammation and atrophy in muscle cells during obesity.

Pellegrinelli V, Rouault C, Rodriguez-Cuenca S, Albert V, Edom-Vovard F, Vidal-Puig A, Clément K, Butler-Browne G, Lacasa D.

Diabetes. 2015 Feb 18. pii: db140796. [Epub ahead of print]


Assessment of left atrial function by MRI myocardial feature tracking.

Evin M, Cluzel P, Lamy J, Rosenbaum D, Kusmia S, Defrance C, Soulat G, Mousseaux E, Roux C, Clement K, Hatem SN, Redheuil A, Kachenoura N.

J Magn Reson Imaging. 2015 Jan 28. doi: 10.1002/jmri.24851. [Epub ahead of print]


Age- and pregnancy-associated DNA methylation changes in mammary epithelial cells.

Huh SJ, Clement K, Jee D, Merlini A, Choudhury S, Maruyama R, Yoo R, Chytil A, Boyle P, Ran FA, Moses HL, Barcellos-Hoff MH, Jackson-Grusby L, Meissner A, Polyak K.

Stem Cell Reports. 2015 Feb 10;4(2):297-311. doi: 10.1016/j.stemcr.2014.12.009. Epub 2015 Jan 22.


Aldosterone promotes cardiac endothelial cell proliferation in vivo.

Gravez B, Tarjus A, Pelloux V, Ouvrard-Pascaud A, Delcayre C, Samuel J, Clément K, Farman N, Jaisser F, Messaoudi S.

J Am Heart Assoc. 2015 Jan 6;4(1):e001266. doi: 10.1161/JAHA.114.001266.


Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia.

Landau DA, Clement K, Ziller MJ, Boyle P, Fan J, Gu H, Stevenson K, Sougnez C, Wang L, Li S, Kotliar D, Zhang W, Ghandi M, Garraway L, Fernandes SM, Livak KJ, Gabriel S, Gnirke A, Lander ES, Brown JR, Neuberg D, Kharchenko PV, Hacohen N, Getz G, Meissner A, Wu CJ.

Cancer Cell. 2014 Dec 8;26(6):813-25. doi: 10.1016/j.ccell.2014.10.012.


Metabolic and adipose tissue signatures in adults with Prader-Willi syndrome: a model of extreme adiposity.

Lacroix D, Moutel S, Coupaye M, Huvenne H, Faucher P, Pelloux V, Rouault C, Bastard JP, Cagnard N, Dubern B, Clément K, Poitou C.

J Clin Endocrinol Metab. 2015 Mar;100(3):850-9. doi: 10.1210/jc.2014-3127. Epub 2014 Dec 5.


Circulating phospholipid profiling identifies portal contribution to NASH signature in obesity.

Anjani K, Lhomme M, Sokolovska N, Poitou C, Aron-Wisnewsky J, Bouillot JL, Lesnik P, Bedossa P, Kontush A, Clement K, Dugail I, Tordjman J.

J Hepatol. 2015 Apr;62(4):905-12. doi: 10.1016/j.jhep.2014.11.002. Epub 2014 Nov 8.


Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells.

Li W, Cavelti-Weder C, Zhang Y, Clement K, Donovan S, Gonzalez G, Zhu J, Stemann M, Xu K, Hashimoto T, Yamada T, Nakanishi M, Zhang Y, Zeng S, Gifford D, Meissner A, Weir G, Zhou Q.

Nat Biotechnol. 2014 Dec;32(12):1223-30. doi: 10.1038/nbt.3082. Epub 2014 Nov 17.


High levels of CRP in morbid obesity: the central role of adipose tissue and lessons for clinical practice before and after bariatric surgery.

Paepegaey AC, Genser L, Bouillot JL, Oppert JM, Clément K, Poitou C.

Surg Obes Relat Dis. 2015 Jan-Feb;11(1):148-54. doi: 10.1016/j.soard.2014.06.010. Epub 2014 Jun 18.


Type 2 Diabetes Remission After Gastric Bypass: What Is the Best Prediction Tool for Clinicians?

Cotillard A, Poitou C, Duchâteau-Nguyen G, Aron-Wisnewsky J, Bouillot JL, Schindler T, Clément K.

Obes Surg. 2014 Nov 12. [Epub ahead of print]


Dietary patterns differently associate with inflammation and gut microbiota in overweight and obese subjects.

Kong LC, Holmes BA, Cotillard A, Habi-Rachedi F, Brazeilles R, Gougis S, Gausserès N, Cani PD, Fellahi S, Bastard JP, Kennedy SP, Doré J, Ehrlich SD, Zucker JD, Rizkalla SW, Clément K.

PLoS One. 2014 Oct 20;9(10):e109434. doi: 10.1371/journal.pone.0109434. eCollection 2014.


Associations between genetic obesity susceptibility and early postnatal fat and lean mass: an individual participant meta-analysis.

Elks CE, Heude B, de Zegher F, Barton SJ, Clément K, Inskip HM, Koudou Y, Cooper C, Dunger DB, Ibáñez L, Charles MA, Ong KK.

JAMA Pediatr. 2014 Dec;168(12):1122-30. doi: 10.1001/jamapediatrics.2014.1619.

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