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Results: 1 to 20 of 113

1.

Biochemistry: Unexpected role for vitamin B2.

Clarke CF, Allan CM.

Nature. 2015 Jun 25;522(7557):427-8. doi: 10.1038/nature14536. Epub 2015 Jun 17. No abstract available.

PMID:
26083748
2.

Yeast Coq9 controls deamination of coenzyme Q intermediates that derive from para-aminobenzoic acid.

He CH, Black DS, Nguyen TP, Wang C, Srinivasan C, Clarke CF.

Biochim Biophys Acta. 2015 Sep;1851(9):1227-39. doi: 10.1016/j.bbalip.2015.05.003. Epub 2015 May 23.

PMID:
26008578
3.

Resveratrol and para-coumarate serve as ring precursors for coenzyme Q biosynthesis.

Xie LX, Williams KJ, He CH, Weng E, Khong S, Rose TE, Kwon O, Bensinger SJ, Marbois BN, Clarke CF.

J Lipid Res. 2015 Apr;56(4):909-19. doi: 10.1194/jlr.M057919. Epub 2015 Feb 14.

PMID:
25681964
4.

Identification of Coq11, a new coenzyme Q biosynthetic protein in the CoQ-synthome in Saccharomyces cerevisiae.

Allan CM, Awad AM, Johnson JS, Shirasaki DI, Wang C, Blaby-Haas CE, Merchant SS, Loo JA, Clarke CF.

J Biol Chem. 2015 Mar 20;290(12):7517-34. doi: 10.1074/jbc.M114.633131. Epub 2015 Jan 28.

PMID:
25631044
5.

Isotope-reinforced polyunsaturated fatty acids protect mitochondria from oxidative stress.

Andreyev AY, Tsui HS, Milne GL, Shmanai VV, Bekish AV, Fomich MA, Pham MN, Nong Y, Murphy AN, Clarke CF, Shchepinov MS.

Free Radic Biol Med. 2015 May;82:63-72. doi: 10.1016/j.freeradbiomed.2014.12.023. Epub 2015 Jan 8.

PMID:
25578654
6.

Reply to Wang et al response to 'Evaluation of New Zealand's bicycle helmet law' article.

Clarke CF.

N Z Med J. 2014 Sep 12;127(1402):113-6. No abstract available.

PMID:
25228427
7.

Molecular characterization of the human COQ5 C-methyltransferase in coenzyme Q10 biosynthesis.

Nguyen TP, Casarin A, Desbats MA, Doimo M, Trevisson E, Santos-Ocaña C, Navas P, Clarke CF, Salviati L.

Biochim Biophys Acta. 2014 Nov;1841(11):1628-38. doi: 10.1016/j.bbalip.2014.08.007. Epub 2014 Aug 23.

8.

The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.

Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, Diep S, Lomenick B, Meli VS, Monsalve GC, Hu E, Whelan SA, Wang JX, Jung G, Solis GM, Fazlollahi F, Kaweeteerawat C, Quach A, Nili M, Krall AS, Godwin HA, Chang HR, Faull KF, Guo F, Jiang M, Trauger SA, Saghatelian A, Braas D, Christofk HR, Clarke CF, Teitell MA, Petrascheck M, Reue K, Jung ME, Frand AR, Huang J.

Nature. 2014 Jun 19;510(7505):397-401. doi: 10.1038/nature13264. Epub 2014 May 14.

9.

Osmotic stress: Is CoQ a membrane stabilizer?

Clarke CF, Rowat AC, Gober JW.

Nat Chem Biol. 2014 Apr;10(4):242-3. doi: 10.1038/nchembio.1478. No abstract available.

PMID:
24643237
10.

Coenzyme Q supplementation or over-expression of the yeast Coq8 putative kinase stabilizes multi-subunit Coq polypeptide complexes in yeast coq null mutants.

He CH, Xie LX, Allan CM, Tran UC, Clarke CF.

Biochim Biophys Acta. 2014 Apr 4;1841(4):630-44. doi: 10.1016/j.bbalip.2013.12.017. Epub 2014 Jan 7.

11.

Unusual kinetic isotope effects of deuterium reinforced polyunsaturated fatty acids in tocopherol-mediated free radical chain oxidations.

Lamberson CR, Xu L, Muchalski H, Montenegro-Burke JR, Shmanai VV, Bekish AV, McLean JA, Clarke CF, Shchepinov MS, Porter NA.

J Am Chem Soc. 2014 Jan 22;136(3):838-41. doi: 10.1021/ja410569g. Epub 2014 Jan 8.

PMID:
24380377
12.

ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption.

Ashraf S, Gee HY, Woerner S, Xie LX, Vega-Warner V, Lovric S, Fang H, Song X, Cattran DC, Avila-Casado C, Paterson AD, Nitschké P, Bole-Feysot C, Cochat P, Esteve-Rudd J, Haberberger B, Allen SJ, Zhou W, Airik R, Otto EA, Barua M, Al-Hamed MH, Kari JA, Evans J, Bierzynska A, Saleem MA, Böckenhauer D, Kleta R, El Desoky S, Hacihamdioglu DO, Gok F, Washburn J, Wiggins RC, Choi M, Lifton RP, Levy S, Han Z, Salviati L, Prokisch H, Williams DS, Pollak M, Clarke CF, Pei Y, Antignac C, Hildebrandt F.

J Clin Invest. 2013 Dec;123(12):5179-89. doi: 10.1172/JCI69000. Epub 2013 Nov 25.

13.

Focal segmental glomerulosclerosis is associated with a PDSS2 haplotype and, independently, with a decreased content of coenzyme Q10.

Gasser DL, Winkler CA, Peng M, An P, McKenzie LM, Kirk GD, Shi Y, Xie LX, Marbois BN, Clarke CF, Kopp JB.

Am J Physiol Renal Physiol. 2013 Oct 15;305(8):F1228-38. doi: 10.1152/ajprenal.00143.2013. Epub 2013 Aug 7.

14.

Functional imaging for interpretation of pain pathways: current clinical application/relevance and future initiatives.

Clarke CF, Lawrence KS.

Curr Pain Headache Rep. 2013 Feb;17(2):311. doi: 10.1007/s11916-012-0311-x. Review.

PMID:
23315051
15.

A conserved START domain coenzyme Q-binding polypeptide is required for efficient Q biosynthesis, respiratory electron transport, and antioxidant function in Saccharomyces cerevisiae.

Allan CM, Hill S, Morvaridi S, Saiki R, Johnson JS, Liau WS, Hirano K, Kawashima T, Ji Z, Loo JA, Shepherd JN, Clarke CF.

Biochim Biophys Acta. 2013 Apr;1831(4):776-91. doi: 10.1016/j.bbalip.2012.12.007. Epub 2012 Dec 25.

16.

Delayed accumulation of intestinal coliform bacteria enhances life span and stress resistance in Caenorhabditis elegans fed respiratory deficient E. coli.

Gomez F, Monsalve GC, Tse V, Saiki R, Weng E, Lee L, Srinivasan C, Frand AR, Clarke CF.

BMC Microbiol. 2012 Dec 20;12:300. doi: 10.1186/1471-2180-12-300.

17.

Case report: Emergence of autochthonous cutaneous leishmaniasis in northeastern Texas and southeastern Oklahoma.

Clarke CF, Bradley KK, Wright JH, Glowicz J.

Am J Trop Med Hyg. 2013 Jan;88(1):157-61. doi: 10.4269/ajtmh.2012.11-0717. Epub 2012 Nov 26.

18.

Folate status of gut microbiome affects Caenorhabditis elegans lifespan.

Nguyen TP, Clarke CF.

BMC Biol. 2012 Jul 31;10:66. doi: 10.1186/1741-7007-10-66.

19.

Restoring de novo coenzyme Q biosynthesis in Caenorhabditis elegans coq-3 mutants yields profound rescue compared to exogenous coenzyme Q supplementation.

Gomez F, Saiki R, Chin R, Srinivasan C, Clarke CF.

Gene. 2012 Sep 10;506(1):106-16. doi: 10.1016/j.gene.2012.06.023. Epub 2012 Jun 23.

20.

Small amounts of isotope-reinforced polyunsaturated fatty acids suppress lipid autoxidation.

Hill S, Lamberson CR, Xu L, To R, Tsui HS, Shmanai VV, Bekish AV, Awad AM, Marbois BN, Cantor CR, Porter NA, Clarke CF, Shchepinov MS.

Free Radic Biol Med. 2012 Aug 15;53(4):893-906. doi: 10.1016/j.freeradbiomed.2012.06.004. Epub 2012 Jun 15.

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