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Items: 1 to 20 of 29


Exploration of a physiologically-inspired hearing-aid algorithm using a computer model mimicking impaired hearing.

Jürgens T, Clark NR, Lecluyse W, Meddis R.

Int J Audiol. 2016 Jun;55(6):346-57. doi: 10.3109/14992027.2015.1135352. Epub 2016 Feb 26.


Principal Angle Enrichment Analysis (PAEA): Dimensionally Reduced Multivariate Gene Set Enrichment Analysis Tool.

Clark NR, Szymkiewicz M, Wang Z, Monteiro CD, Jones MR, Ma'ayan A.

Proceedings (IEEE Int Conf Bioinformatics Biomed). 2015 Nov;2015:256-262.


Dynamics of the discovery process of protein-protein interactions from low content studies.

Wang Z, Clark NR, Ma'ayan A.

BMC Syst Biol. 2015 Jun 6;9:26. doi: 10.1186/s12918-015-0173-z.


Scaffold hopping approach on the route to selective tankyrase inhibitors.

Liscio P, Carotti A, Asciutti S, Ferri M, Pires MM, Valloscuro S, Ziff J, Clark NR, Macchiarulo A, Aaronson SA, Pellicciari R, Camaioni E.

Eur J Med Chem. 2014 Nov 24;87:611-23. doi: 10.1016/j.ejmech.2014.10.007. Epub 2014 Oct 5.


Lean Big Data integration in systems biology and systems pharmacology.

Ma'ayan A, Rouillard AD, Clark NR, Wang Z, Duan Q, Kou Y.

Trends Pharmacol Sci. 2014 Sep;35(9):450-60. doi: 10.1016/ Epub 2014 Aug 7.


Proteomics analysis of the non-muscle myosin heavy chain IIa-enriched actin-myosin complex reveals multiple functions within the podocyte.

Hays T, Ma'ayan A, Clark NR, Tan CM, Teixeira A, Teixeira A, Choi JW, Burdis N, Jung SY, Bajaj AO, O'Malley BW, He JC, Hyink DP, Klotman PE.

PLoS One. 2014 Jun 20;9(6):e100660. doi: 10.1371/journal.pone.0100660. eCollection 2014.


The characteristic direction: a geometrical approach to identify differentially expressed genes.

Clark NR, Hu KS, Feldmann AS, Kou Y, Chen EY, Duan Q, Ma'ayan A.

BMC Bioinformatics. 2014 Mar 21;15:79. doi: 10.1186/1471-2105-15-79.


The robustness of speech representations obtained from simulated auditory nerve fibers under different noise conditions.

Jürgens T, Brand T, Clark NR, Meddis R, Brown GJ.

J Acoust Soc Am. 2013 Sep;134(3):EL282-8. doi: 10.1121/1.4817912.


Metasignatures identify two major subtypes of breast cancer.

Duan Q, Kou Y, Clark NR, Gordonov S, Ma'ayan A.

CPT Pharmacometrics Syst Pharmacol. 2013 Mar 27;2:e35. doi: 10.1038/psp.2013.11.


Induction of a hemogenic program in mouse fibroblasts.

Pereira CF, Chang B, Qiu J, Niu X, Papatsenko D, Hendry CE, Clark NR, Nomura-Kitabayashi A, Kovacic JC, Ma'ayan A, Schaniel C, Lemischka IR, Moore K.

Cell Stem Cell. 2013 Aug 1;13(2):205-18. doi: 10.1016/j.stem.2013.05.024. Epub 2013 Jun 13.


Network2Canvas: network visualization on a canvas with enrichment analysis.

Tan CM, Chen EY, Dannenfelser R, Clark NR, Ma'ayan A.

Bioinformatics. 2013 Aug 1;29(15):1872-8. doi: 10.1093/bioinformatics/btt319. Epub 2013 Jun 7.


A computer model of the auditory periphery and its application to the study of hearing.

Meddis R, Lecluyse W, Clark NR, Jürgens T, Tan CM, Panda MR, Brown GJ.

Adv Exp Med Biol. 2013;787:11-9; discussion 19-20. doi: 10.1007/978-1-4614-1590-9_2. Review.


Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool.

Chen EY, Tan CM, Kou Y, Duan Q, Wang Z, Meirelles GV, Clark NR, Ma'ayan A.

BMC Bioinformatics. 2013 Apr 15;14:128. doi: 10.1186/1471-2105-14-128.


Renoprotective effect of combined inhibition of angiotensin-converting enzyme and histone deacetylase.

Zhong Y, Chen EY, Liu R, Chuang PY, Mallipattu SK, Tan CM, Clark NR, Deng Y, Klotman PE, Ma'ayan A, He JC.

J Am Soc Nephrol. 2013 Apr;24(5):801-11. doi: 10.1681/ASN.2012060590. Epub 2013 Apr 4.


A frequency-selective feedback model of auditory efferent suppression and its implications for the recognition of speech in noise.

Clark NR, Brown GJ, Jürgens T, Meddis R.

J Acoust Soc Am. 2012 Sep;132(3):1535-41.


Interprofessional collaborative model for medication therapy management (MTM) services to improve health care access and quality for underserved populations.

Truong HA, Groves CN, Congdon HB, Botchway R, Dang DT, Clark NR, Zarfeshan F.

J Health Care Poor Underserved. 2012 Aug;23(3 Suppl):114-24. doi: 10.1353/hpu.2012.0126.


Sets2Networks: network inference from repeated observations of sets.

Clark NR, Dannenfelser R, Tan CM, Komosinski ME, Ma'ayan A.

BMC Syst Biol. 2012 Jul 23;6:89. doi: 10.1186/1752-0509-6-89.


Genes2FANs: connecting genes through functional association networks.

Dannenfelser R, Clark NR, Ma'ayan A.

BMC Bioinformatics. 2012 Jul 2;13:156. doi: 10.1186/1471-2105-13-156.


Recovering protein-protein and domain-domain interactions from aggregation of IP-MS proteomics of coregulator complexes.

Mazloom AR, Dannenfelser R, Clark NR, Grigoryan AV, Linder KM, Cardozo TJ, Bond JC, Boran AD, Iyengar R, Malovannaya A, Lanz RB, Ma'ayan A.

PLoS Comput Biol. 2011 Dec;7(12):e1002319. doi: 10.1371/journal.pcbi.1002319. Epub 2011 Dec 29.


Introduction to statistical methods for analyzing large data sets: gene-set enrichment analysis.

Clark NR, Ma'ayan A.

Sci Signal. 2011 Sep 6;4(190):tr4. doi: 10.1126/scisignal.2001966.

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